CLL Prognosis and Survival

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Questions and Answers

What is the median survival period for patients with CLL?

  • 5 years
  • 20 years
  • 2 years
  • 10 years (correct)

What is the significance of lymphocyte doubling time in CLL?

  • It is a prognostic factor of CLL (correct)
  • It is a diagnostic factor of CLL
  • It is a treatment factor of CLL
  • It is a curative factor of CLL

What is lymphocyte doubling time defined as?

  • The number of months it takes to double the absolute lymphocyte count (correct)
  • The number of months it takes to triple the absolute lymphocyte count
  • The number of months it takes to halve the absolute lymphocyte count
  • The number of months it takes to quadruple the absolute lymphocyte count

Patients with CLL who present as Rai stage 0-II may survive for how long without treatment?

<p>5 to 20 years (A)</p> Signup and view all the answers

What is the characteristic of CLL in untreated patients with a lymphocyte doubling time of less than 6 months?

<p>A more aggressive expression (C)</p> Signup and view all the answers

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Study Notes

Chronic Lymphocytic Leukemia (CLL) Survival

  • Survival for patients with CLL can vary significantly, ranging from 2 to over 20 years.
  • The median survival rate for CLL patients is approximately 10 years.
  • Patients diagnosed at Rai stage 0-II have a favorable prognosis, potentially surviving between 5 to 20 years without treatment.

Prognostic Factors

  • Lymphocyte doubling time serves as a crucial prognostic factor in CLL.
  • This measure indicates the months required for the absolute lymphocyte count to double.
  • Untreated patients exhibiting a shorter lymphocyte doubling time tend to have a more aggressive form of CLL.

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