Clinical Trials Phase III Overview

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Questions and Answers

Which classification of chemotherapeutic agents includes drugs that interfere with DNA replication by forming covalent bonds with DNA?

  • Antimetabolites
  • Nitrosureas (correct)
  • Hormonal agents
  • Plant alkaloids

What is the mechanism of action of antimetabolites in chemotherapy?

  • Inhibition of hormone production
  • Disruption of cell membrane integrity
  • Interference with DNA synthesis (correct)
  • Inhibition of microtubule function

Which route of administration for chemotherapeutic agents involves injecting drugs directly into the spinal canal?

  • Intramuscular
  • Intrathecal (correct)
  • Intravenous
  • Arterial

What is the primary goal of combined medication therapy in chemotherapy?

<p>Reducing drug resistance mechanisms (B)</p> Signup and view all the answers

Which category of chemotherapeutic agents is derived from natural sources like plants?

<p>Antitumor antibiotics (C)</p> Signup and view all the answers

Levamisole, leucovorin, and hormones are examples of which type of chemotherapeutic agents?

<p>Miscellaneous agents (C)</p> Signup and view all the answers

What is a common use of hormonal agents in chemotherapy?

<p>Blocking hormone receptors on cancer cells (A)</p> Signup and view all the answers

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