Clinical Trials Phase III Overview
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Questions and Answers

Which classification of chemotherapeutic agents includes drugs that interfere with DNA replication by forming covalent bonds with DNA?

  • Antimetabolites
  • Nitrosureas (correct)
  • Hormonal agents
  • Plant alkaloids

    • What is the mechanism of action of antimetabolites in chemotherapy?

  • Inhibition of hormone production
  • Disruption of cell membrane integrity
  • Interference with DNA synthesis (correct)
  • Inhibition of microtubule function

    • Which route of administration for chemotherapeutic agents involves injecting drugs directly into the spinal canal?

  • Intramuscular
  • Intrathecal (correct)
  • Intravenous
  • Arterial

    • What is the primary goal of combined medication therapy in chemotherapy?

    <p>Reducing drug resistance mechanisms</p> Signup and view all the answers

    Which category of chemotherapeutic agents is derived from natural sources like plants?

    <p>Antitumor antibiotics</p> Signup and view all the answers

    Levamisole, leucovorin, and hormones are examples of which type of chemotherapeutic agents?

    <p>Miscellaneous agents</p> Signup and view all the answers

    What is a common use of hormonal agents in chemotherapy?

    <p>Blocking hormone receptors on cancer cells</p> Signup and view all the answers

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