Clinical Pharmacy Fourth Year: Respiratory Disorders - Asthma Pathophysiology
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Questions and Answers

What is asthma defined as by the Global Initiative for Asthma (GINA)?

  • A condition marked by sudden, severe chest pain
  • A heterogeneous disease usually characterized by chronic airway inflammation (correct)
  • An autoimmune disorder affecting the respiratory system
  • A disease characterized by chronic lung infections

    • Which of the following is NOT a characteristic of asthma according to the text?

  • Persistent chest tightness
  • High fever (correct)
  • Variable expiratory airflow limitation
  • Frequent episodes of wheezing

    • What is one of the pathophysiological mechanisms of asthma described in the text?

  • Release of proinflammatory mediators causing bronchospasm and edema (correct)
  • Constriction of large blood vessels in the lungs
  • Decreased production of mucus in the airways
  • Activation of platelets leading to blood clot formation

    • Which clinical presentation is associated with chronic asthma?

    <p>Episodes of shortness of breath and chest tightness</p> Signup and view all the answers

    What may patients with acute severe asthma complain about according to the text?

    <p>Shortness of breath, chest tightness, or burning</p> Signup and view all the answers

    Which inflammatory cells are involved in the pathophysiology of asthma mentioned in the text?

    <p>Mast cells</p> Signup and view all the answers

    What is one effect of proinflammatory mediators released during asthma inflammation according to the text?

    <p>Increased mucus production</p> Signup and view all the answers

    When does uncontrolled asthma progress to an acute state according to the text?

    <p>When patients experience acute distress and severe dyspnea</p> Signup and view all the answers

    What is the main characteristic used to define asthma by the Global Initiative for Asthma?

    <p>Shortness of breath</p> Signup and view all the answers

    Which of the following is NOT an effect induced by proinflammatory mediators released during asthma inflammation?

    <p>Increased airway diameter</p> Signup and view all the answers

    What is the main symptom associated with chronic asthma episodes?

    <p>Shortness of breath</p> Signup and view all the answers

    Which cells are responsible for inducing contraction of airway smooth muscle during asthma inflammation?

    <p>Mast cells</p> Signup and view all the answers

    What might patients with acute severe asthma mainly complain about during an acute state?

    <p>Severe chest tightness</p> Signup and view all the answers

    Which of the following signs is commonly associated with uncontrolled asthma progressing to an acute state?

    <p>Anxious behavior</p> Signup and view all the answers

    What is one of the outcomes of mucus secretion during asthma inflammation?

    <p>Constricted airways</p> Signup and view all the answers

    Which symptom is particularly noticeable at night in patients with chronic asthma?

    <p>Shortness of breath</p> Signup and view all the answers

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