Podcast
Questions and Answers
What is the primary mechanism of action of local anesthetic agents?
What is the primary mechanism of action of local anesthetic agents?
- Blocking the voltage-gated sodium channels (correct)
- Blocking the release of neurotransmitters from nerve terminals
- Depolarizing the neuronal membrane
- Inhibiting the reuptake of dopamine
Which of the following types of local anesthetics is characterized by an amide linkage in its chemical structure?
Which of the following types of local anesthetics is characterized by an amide linkage in its chemical structure?
- Ester-type local anesthetics
- Amide-type local anesthetics (correct)
- Amine-type local anesthetics
- Ketone-type local anesthetics
What is the primary route of elimination of local anesthetic agents?
What is the primary route of elimination of local anesthetic agents?
- Hepatic metabolism (correct)
- Fecal excretion
- Biliary excretion
- Renal excretion
What is the primary clinical application of local anesthetic agents?
What is the primary clinical application of local anesthetic agents?
What is the primary pharmacodynamic effect of local anesthetic agents?
What is the primary pharmacodynamic effect of local anesthetic agents?
Which of the following local anesthetic agents is most likely to cause methemoglobinemia?
Which of the following local anesthetic agents is most likely to cause methemoglobinemia?
What is the primary mechanism by which local anesthetics produce vasodilation?
What is the primary mechanism by which local anesthetics produce vasodilation?
Which of the following types of nerve fibers is most resistant to the effects of local anesthetic agents?
Which of the following types of nerve fibers is most resistant to the effects of local anesthetic agents?
What is the primary factor determining the duration of action of local anesthetic agents?
What is the primary factor determining the duration of action of local anesthetic agents?
Which of the following local anesthetic agents is most likely to cause central nervous system toxicity at clinically relevant doses?
Which of the following local anesthetic agents is most likely to cause central nervous system toxicity at clinically relevant doses?
