Clinical Pharmacokinetics of Local Anaesthetics
10 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary mechanism of action of local anesthetic agents?

  • Blocking the voltage-gated sodium channels (correct)
  • Blocking the release of neurotransmitters from nerve terminals
  • Depolarizing the neuronal membrane
  • Inhibiting the reuptake of dopamine

    • Which of the following types of local anesthetics is characterized by an amide linkage in its chemical structure?

  • Ester-type local anesthetics
  • Amide-type local anesthetics (correct)
  • Amine-type local anesthetics
  • Ketone-type local anesthetics

    • What is the primary route of elimination of local anesthetic agents?

  • Hepatic metabolism (correct)
  • Fecal excretion
  • Biliary excretion
  • Renal excretion

    • What is the primary clinical application of local anesthetic agents?

    <p>Anesthesia for surgical procedures</p> Signup and view all the answers

    What is the primary pharmacodynamic effect of local anesthetic agents?

    <p>Analgesia</p> Signup and view all the answers

    Which of the following local anesthetic agents is most likely to cause methemoglobinemia?

    <p>Benzocaine</p> Signup and view all the answers

    What is the primary mechanism by which local anesthetics produce vasodilation?

    <p>Blockade of alpha-1 adrenergic receptors</p> Signup and view all the answers

    Which of the following types of nerve fibers is most resistant to the effects of local anesthetic agents?

    <p>C-fibers</p> Signup and view all the answers

    What is the primary factor determining the duration of action of local anesthetic agents?

    <p>Protein binding</p> Signup and view all the answers

    Which of the following local anesthetic agents is most likely to cause central nervous system toxicity at clinically relevant doses?

    <p>Bupivacaine</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser