Clinical Neuroscience Quiz

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Questions and Answers

Hemispatial neglect is most commonly associated with damage to which brain region?

  • Prefrontal cortex
  • Occipital lobe
  • Right parietal lobe (correct)
  • Left parietal lobe

Balint's syndrome involves which of the following symptoms?

  • Inability to move the eyes
  • Loss of depth perception
  • Difficulty in visual attention to multiple objects
  • All of the above (correct)

What is the primary neurotransmitter involved in depression?

  • Serotonin (correct)
  • Dopamine
  • Acetylcholine
  • GABA

In PTSD, the hyperactivation of which brain structure is most significant?

<p>Amygdala (B)</p> Signup and view all the answers

Which of the following is a hallmark feature of fetal alcohol syndrome (FAS)?

<p>Distinct facial dysmorphology (C)</p> Signup and view all the answers

The term "anosognosia" refers to:

<p>Unawareness of a deficit or condition (D)</p> Signup and view all the answers

Which brain region is primarily responsible for integrating sensory information in hemispatial neglect?

<p>Angular gyrus (C)</p> Signup and view all the answers

What is the most common cause of traumatic brain injury (TBI)?

<p>Motor vehicle accidents (A)</p> Signup and view all the answers

A patient with Balint's syndrome is most likely to demonstrate:

<p>Both B and C (D)</p> Signup and view all the answers

Which of the following neuroimaging techniques is best suited to detect white matter abnormalities in TBI?

<p>Diffusion tensor imaging (DTI) (D)</p> Signup and view all the answers

Which neurotransmitter system is most disrupted in Parkinson's disease?

<p>Dopamine (C)</p> Signup and view all the answers

The "default mode network" (DMN) in the brain is typically active during:

<p>Rest or introspection (A)</p> Signup and view all the answers

Which of the following is a major symptom of post-concussion syndrome?

<p>Persistent headaches (C)</p> Signup and view all the answers

In depression, atrophy is often observed in which brain structure?

<p>Hippocampus (C)</p> Signup and view all the answers

Which of the following is not part of the diagnostic triad for autism spectrum disorder?

<p>Impaired motor coordination (D)</p> Signup and view all the answers

Which therapeutic approach is most commonly used for treating PTSD?

<p>Cognitive-behavioral therapy (CBT) (D)</p> Signup and view all the answers

The phenomenon where a patient believes their limb does not belong to them is called:

<p>Somatoparaphrenia (C)</p> Signup and view all the answers

Which neural pathway is primarily involved in reward and motivation?

<p>Mesolimbic pathway (A)</p> Signup and view all the answers

Which of the following is a common feature of Korsakoff's syndrome?

<p>Both A and B (C)</p> Signup and view all the answers

The hallmark of "resting tremor" is associated with which condition?

<p>Parkinson's disease (D)</p> Signup and view all the answers

Damage to which area of the brain is associated with Broca's aphasia?

<p>Left inferior frontal gyrus (D)</p> Signup and view all the answers

What is the primary role of the hippocampus?

<p>Memory consolidation (D)</p> Signup and view all the answers

Which of the following is considered a positive symptom of schizophrenia?

<p>Hallucinations (B)</p> Signup and view all the answers

Which brain region is primarily involved in decision-making and impulse control?

<p>Ventromedial prefrontal cortex (B)</p> Signup and view all the answers

What is a key distinguishing feature of Huntington's disease?

<p>Chorea (C)</p> Signup and view all the answers

Which imaging technique provides the most detailed structural view of the brain?

<p>MRI (B)</p> Signup and view all the answers

A patient with damage to the ventral visual stream is likely to experience:

<p>Object agnosia (B)</p> Signup and view all the answers

In traumatic brain injury, diffuse axonal injury is best described as:

<p>Shearing of white matter tracts (B)</p> Signup and view all the answers

Which neurotransmitter is primarily affected in Alzheimer's disease?

<p>Acetylcholine (B)</p> Signup and view all the answers

Which brain region is crucial for fear processing?

<p>Amygdala (C)</p> Signup and view all the answers

Which of the following is a characteristic of Balint's syndrome?

<p>Visual disorientation (C)</p> Signup and view all the answers

What type of memory is most impacted by damage to the hippocampus?

<p>Declarative memory (D)</p> Signup and view all the answers

Which condition is associated with the presence of Lewy bodies in the brain?

<p>Parkinson's disease (B)</p> Signup and view all the answers

Which of the following is NOT a feature of Wernicke's aphasia?

<p>Motor speech impairment (D)</p> Signup and view all the answers

The "mirror neuron system" is believed to play a critical role in:

<p>Social cognition and empathy (D)</p> Signup and view all the answers

Which of the following is a primary characteristic of REM sleep?

<p>Muscle atonia (D)</p> Signup and view all the answers

Which neuroimaging technique directly measures neural activity?

<p>EEG (B)</p> Signup and view all the answers

A lesion to the ventromedial prefrontal cortex is most likely to result in:

<p>Impaired emotional decision-making (C)</p> Signup and view all the answers

Which condition involves progressive demyelination in the central nervous system?

<p>Multiple sclerosis (B)</p> Signup and view all the answers

The "split-brain" phenomenon occurs after surgical severing of:

<p>Corpus callosum (C)</p> Signup and view all the answers

Flashcards

Anosognosia

A condition characterized by a lack of awareness of a disability or condition.

Balint's Syndrome

A neurological disorder affecting visual attention, characterized by difficulty in shifting attention to multiple objects simultaneously.

Parietal Lobe

A region of the brain responsible for processing sensory information from the opposite side of the body, crucial for spatial awareness.

Prosopagnosia

The inability to recognize faces, despite intact vision.

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Serotonin

A neurotransmitter heavily involved in mood regulation, sleep, and appetite.

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Default Mode Network (DMN)

A complex network of brain regions activated during rest, introspection, and mind-wandering.

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Parkinson's Disease

A neurodegenerative disorder characterized by tremors, stiffness, slow movements, and impaired balance.

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MRI

A neuroimaging technique that uses magnetic fields to produce detailed images of brain structures.

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Amygdala

A key brain region involved in fear processing and emotional learning.

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Dopamine

The primary neurotransmitter affected in Parkinson's disease, responsible for regulating movement control.

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Hemispatial Neglect

The inability to attend to the left side of space, often as a result of damage to the right parietal lobe.

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Diffuse Axonal Injury

A severe brain injury caused by rapid acceleration or deceleration forces, often leading to widespread axonal damage.

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Broca's Aphasia

A disorder characterized by difficulty with language production, often caused by damage to the left inferior frontal gyrus.

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fMRI

A neuroimaging technique used to measure brain activity by detecting changes in blood flow.

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Memory Consolidation

The process of converting short-term memories into long-term memories, primarily regulated by the hippocampus.

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Acetylcholine

A neurotransmitter crucial for learning and memory, often targeted in Alzheimer's disease.

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Chorea

A neurological condition marked by involuntary, jerky movements, often associated with damage to the basal ganglia.

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Declarative Memory

A type of long-term memory that stores personal experiences and facts.

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Wernicke's Aphasia

A condition characterized by a loss of language comprehension, often associated with damage to Wernicke's area.

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Hippocampus

The primary brain region involved in memory consolidation and spatial navigation.

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GABA

A neurotransmitter crucial for regulating anxiety and sleep.

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Amyotrophic Lateral Sclerosis (ALS)

A condition characterized by progressive loss of motor neurons, leading to muscle weakness and paralysis.

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Object Agnosia

A condition involving an inability to recognize objects, despite intact vision, often caused by damage to the ventral visual stream.

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Somatoparaphrenia

The phenomenon where a patient believes their limb is not their own.

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Alzheimer's Disease

A neurodegenerative disorder characterized by progressive cognitive decline, memory loss, and behavioral changes.

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Post-concussion Syndrome

A collection of symptoms that persist after a concussion, including headaches, dizziness, and cognitive impairments.

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PET Scan

A neuroimaging technique that uses radioactive tracers to map brain activity and metabolism.

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Korsakoff's Syndrome

A neurological condition characterized by confusion, short-term memory loss, and confabulation, often associated with thiamine deficiency.

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Angular Gyrus

A brain structure that plays a significant role in integrating sensory information, especially for spatial awareness.

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Schizophrenia

A condition characterized by a range of symptoms, including hallucinations, delusions, disorganized thinking, and social withdrawal.

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Huntington's Disease

A neurodegenerative disorder characterized by involuntary, repetitive movements, cognitive decline, and personality changes.

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Autotopagnosia

A neurological condition marked by a loss of awareness of one's body or body parts.

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Resting Tremor

A primary feature of Parkinson's disease, characterized by resting tremors, particularly in the hands.

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Ventromedial Prefrontal Cortex

A brain structure considered crucial for decision-making, impulse control, and social behavior.

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EEG

A neuroimaging technique that measures electrical activity in the brain.

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Multiple Sclerosis

A neurological disorder characterized by demyelination of nerve fibers, leading to various neurological symptoms.

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Dopamine

A neurotransmitter involved in learning, memory, and motivation, sometimes targeted in addiction therapies.

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Muscle Atonia

A primary characteristic of REM sleep, characterized by muscle paralysis and vivid dreaming.

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Split-Brain

A surgical procedure involving the severing of the corpus callosum, often performed to treat severe epilepsy.

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Procedural Memory

A type of long-term memory that stores skills and procedures.

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Mesolimbic Pathway

A cluster of brain regions responsible for reward and motivation, primarily the ventral tegmental area and the nucleus accumbens.

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CT Scan

A neuroimaging technique that relies on X-rays to create images of the brain.

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Corticospinal Tract

The primary neural pathway responsible for voluntary motor control.

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Mirror Neuron System

A set of neurons located in the premotor cortex that are active when observing actions and also during the performance of those actions.

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Sensory Memory

A type of memory that involves a brief sensory imprint, lasting only a few seconds.

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Chorea

A condition characterized by sudden, involuntary movements, often associated with damage to the basal ganglia.

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Short-Term Memory

A type of memory that involves the retention of information for a short period, typically up to 30 seconds.

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Study Notes

Clinical Neuroscience Questions and Answers

  • Hemispatial neglect is most commonly associated with damage to the right parietal lobe.
  • Balint's syndrome involves: difficulty in visually attending to multiple objects, loss of depth perception.
  • The primary neurotransmitter involved in depression is serotonin.
  • In PTSD, the brain structure most significantly affected by hyperactivation is the amygdala.
  • Fetal alcohol syndrome (FAS) is characterized by distinct facial dysmorphology and enlarged brain volume. It's also marked by accelerated developmental milestones.
  • Anosognosia refers to a patient's unawareness of a deficit or condition.
  • The ventralmedial prefrontal cortex is primarily responsible for sensory information integration in hemispatial neglect.

Additional Questions and Answers

  • Traumatic brain injury (TBI) is most commonly caused by motor vehicle accidents.
  • A patient with Balint's syndrome is most likely to have simultanagnosia (difficulty recognizing multiple objects at once) and spatial disorientation.
  • Diffusion tensor imaging (DTI) is the best neuroimaging technique for detecting white matter abnormalities in TBI.
  • The dopamine neurotransmitter system is most disrupted in Parkinson's disease.
  • The default mode network (DMN) is typically active during rest or introspection.
  • Persistent headaches are a major symptom of post-concussion syndrome.
  • Atrophy of the hippocampus and amygdala are often observed in depression.
  • Deficits in social communication, repetitive behaviors, and restricted interests describe the diagnostic triad of autism spectrum disorder.

Additional Questions and Answers (Page 3)

  • Cognitive-behavioral therapy (CBT) is the most commonly used approach for treating PTSD.
  • Somatoparaphrenia describes the phenomenon of a patient believing a limb belongs to someone else.
  • The mesolimbic pathway is primarily involved in reward and motivation.
  • Retrograde amnesia and confabulation are common features of Korsakoff's syndrome.
  • Parkinson's disease is associated with resting tremor.
  • Broca's aphasia arises from damage to the left inferior frontal gyrus.
  • The hippocampus's primary role is in memory consolidation.
  • Hallucinations are a positive symptom of schizophrenia.

Additional Questions and Answers (Page 4)

  • The ventromedial prefrontal cortex plays a significant role in decision-making and impulse control.
  • A defining feature of Huntington's disease is chorea (involuntary, rapid, jerky movements).
  • MRI provides the most detailed structural view of the brain.
  • Damage to the ventral visual stream leads to difficulty with object agnosia (trouble recognizing objects).
  • Diffuse axonal injury in TBI involves shearing of white matter tracts.
  • Acetylcholine is primarily affected in Alzheimer's disease.
  • The amygdala is crucial for fear processing.
  • Visual disorientation is a characteristic of Balint's syndrome.

Additional Questions and Answers (Page 5)

  • Declarative memory is most impacted by damage to the hippocampus.
  • Parkinson's disease is associated with Lewy bodies.
  • Wernicke's aphasia is characterized by fluent but nonsensical speech and comprehension difficulties.
  • The mirror neuron system plays a role in social cognition and empathy.
  • Muscle atonia is a key characteristic of REM sleep.
  • EEG measures neural activity.
  • Impaired emotional decision-making is a potential result of damage to the ventromedial prefrontal cortex.
  • Multiple sclerosis involves progressive demyelination in the central nervous system.

Additional Question and Answer (Page 6)

  • Surgical severing of the corpus callosum leads to the "split-brain" phenomenon.

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