Clinical Medicine Quiz: Pharyngitis Diagnosis
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Questions and Answers

What is the duration of acute pharyngitis?

  • Less than 2 weeks (correct)
  • More than 2 weeks
  • Variable duration
  • More than 4 weeks
  • Which of the following is a viral cause of pharyngitis?

  • Corynebacterium diphtheriae
  • Rhinovirus (correct)
  • Fusobacterium necrophorum
  • Neisseria gonorrhoeae
  • What is the primary goal of the general approach to acute pharyngitis?

  • Treat all cases with antibiotics
  • Rule out serious diagnoses and red flags/alarm symptoms (correct)
  • Identify acute sore throat caused by group A beta-hemolytic streptococcal pharyngitis
  • Determine the specific infectious cause
  • What is the term for the sensation of mucus running down the back of the throat?

    <p>Postnasal drip</p> Signup and view all the answers

    What is the term for inflammation of the pharynx?

    <p>Pharyngitis</p> Signup and view all the answers

    What is the term for a bacterial cause of pharyngitis?

    <p>Fusobacterium necrophorum</p> Signup and view all the answers

    What is the term for a viral cause of pharyngitis that is also associated with cold sores?

    <p>Herpes simplex virus</p> Signup and view all the answers

    What is the term for the sensation of mucus running up the back of the throat from the stomach?

    <p>Gastroesophageal reflux disease</p> Signup and view all the answers

    What is the term for a non-infectious cause of pharyngitis?

    <p>Smoking</p> Signup and view all the answers

    What percentage of pharyngitis cases are caused by the common cold?

    <p>50%</p> Signup and view all the answers

    What is the optimal temperature for the growth of rhinoviruses?

    <p>32.8°C</p> Signup and view all the answers

    What is a complication of the common cold?

    <p>All of the above</p> Signup and view all the answers

    What is the typical duration of symptoms in a common cold?

    <p>7-10 days</p> Signup and view all the answers

    What is the most common cause of the common cold?

    <p>Rhinovirus</p> Signup and view all the answers

    What is a characteristic of the common cold?

    <p>Chest exam is normal</p> Signup and view all the answers

    What is a type of virus that can cause pharyngitis in children?

    <p>All of the above</p> Signup and view all the answers

    What is a common symptom associated with primary HIV infection?

    <p>Diffuse adenopathy</p> Signup and view all the answers

    What is the treatment for the common cold?

    <p>Self-limiting</p> Signup and view all the answers

    What is the most likely cause of pharyngitis, considering the probabilities?

    <p>Viral</p> Signup and view all the answers

    What is the name of the score used to determine the probability of streptococcal pharyngitis?

    <p>Modified Centor score</p> Signup and view all the answers

    What is a possible complication of retropharyngeal abscess?

    <p>All of the above</p> Signup and view all the answers

    What is a possible cause of mucosal burn injury to the pharynx and larynx?

    <p>Recent cocaine smoking</p> Signup and view all the answers

    What is a possible underlying condition associated with weight loss, fevers, and night sweats?

    <p>Lymphoma, head and neck cancers</p> Signup and view all the answers

    What is the primary treatment for a common cold?

    <p>Analgesics/antipyretics</p> Signup and view all the answers

    Which of the following is a recommended preventive measure for the common cold?

    <p>Avoiding sick contacts</p> Signup and view all the answers

    What is the typical finding on physical exam in a patient with a common cold?

    <p>Posterior oropharynx mildly inflamed and erythematous</p> Signup and view all the answers

    What is the recommended humidification method for children with nasal congestion?

    <p>Cool-mist humidifier</p> Signup and view all the answers

    What is the primary symptom of a patient with a common cold?

    <p>Sore throat</p> Signup and view all the answers

    What is the role of lozenges in the management of a common cold?

    <p>To soothe a sore throat</p> Signup and view all the answers

    What is the typical Rinne test finding in conductive hearing loss?

    <p>Bone conduction &gt; Air conduction</p> Signup and view all the answers

    What is the most likely diagnosis for Alex's condition?

    <p>Otitis externa</p> Signup and view all the answers

    What is the pathogen most commonly associated with otitis externa?

    <p>Pseudomonas species</p> Signup and view all the answers

    What is the primary antibiotic used to treat otitis externa?

    <p>Amoxicillin</p> Signup and view all the answers

    What is the typical duration of antibiotic therapy for children with otitis externa?

    <p>10 days</p> Signup and view all the answers

    What is the primary benefit of antibiotic therapy in otitis externa?

    <p>Decrease in pain by day 2-3</p> Signup and view all the answers

    What is the number needed to treat (NNT) to decrease pain by day 2-3 with antibiotic therapy in otitis externa?

    <p>20</p> Signup and view all the answers

    What is the number needed to harm (NNH) for antibiotic therapy in otitis externa?

    <p>14</p> Signup and view all the answers

    What percentage of cases of sore throat are caused by Group A beta-hemolytic streptococci?

    <p>15-30%</p> Signup and view all the answers

    What is the primary goal of prescribing antibiotics in a patient with a common cold?

    <p>To prevent secondary bacterial infections</p> Signup and view all the answers

    Which of the following viruses has a frequency of less than 1% as a cause of sore throat?

    <p>Epstein-Barr virus (EBV)</p> Signup and view all the answers

    What is the clinical syndrome associated with Corynebacterium diphtheriae?

    <p>Diphtheria</p> Signup and view all the answers

    Which of the following is a recommended supportive therapy for children with a common cold?

    <p>Cool-mist humidifiers</p> Signup and view all the answers

    What is the primary benefit of using saline nasal rinse in a patient with a common cold?

    <p>To thin out mucus and make it easier to expel</p> Signup and view all the answers

    Which of the following bacteria has a frequency of 10% as a cause of sore throat?

    <p>Fusobacterium necrophorum</p> Signup and view all the answers

    What is the primary mechanism by which steam inhalation provides relief in a patient with a common cold?

    <p>By relaxing the nasal passages and making breathing easier</p> Signup and view all the answers

    What is the clinical syndrome associated with Herpes Simplex Virus (HSV) 1 and 2?

    <p>Stomatitis, pharyngitis</p> Signup and view all the answers

    Which of the following viruses has a frequency of 5% as a cause of sore throat?

    <p>Adenovirus</p> Signup and view all the answers

    What is the primary role of lozenges in the management of a common cold?

    <p>To soothe the throat and provide temporary relief from discomfort</p> Signup and view all the answers

    What is the primary way to prevent the spread of a common cold?

    <p>By avoiding close contact with people who are sick</p> Signup and view all the answers

    What is the clinical syndrome associated with Neisseria gonorrhoeae?

    <p>Pharyngitis</p> Signup and view all the answers

    What is the significance of the presence of a cloudy, bulging TM with displaced cone of light in the left ear?

    <p>It is a sign of otitis media</p> Signup and view all the answers

    Which of the following viruses has a frequency of 2% as a cause of sore throat?

    <p>Parainfluenza virus</p> Signup and view all the answers

    What is the most likely diagnosis for a patient with symptoms of sore throat, dysphagia, and odynophagia?

    <p>Acute epiglottitis</p> Signup and view all the answers

    What is the potential complication of a retropharyngeal space infection?

    <p>Spread to the parapharyngeal or retropharyngeal spaces</p> Signup and view all the answers

    What is the significance of the presence of posterior cervical nodes that are enlarged and tender to palpation?

    <p>It is a sign of a bacterial infection</p> Signup and view all the answers

    What is the primary goal of the initial evaluation of a patient with acute pharyngitis?

    <p>To rule out alarm symptoms and signs</p> Signup and view all the answers

    What is the significance of a muffled voice in a patient with acute pharyngitis?

    <p>It is a sign of peritonsillar abscess</p> Signup and view all the answers

    What is the potential complication of a parapharyngeal space infection?

    <p>Spread to the mediastinum</p> Signup and view all the answers

    What is the significance of the presence of nasal turbinates that are red and swollen?

    <p>It is a sign of a viral infection</p> Signup and view all the answers

    What is the primary goal of identifying alarm symptoms in acute pharyngitis?

    <p>To prompt emergent or urgent management of serious diagnoses</p> Signup and view all the answers

    A patient presents with a recent onset sore throat. Which of the following is the most likely cause of pharyngitis?

    <p>Viral pharyngitis</p> Signup and view all the answers

    What is the primary difference between acute and chronic pharyngitis?

    <p>The duration of symptoms</p> Signup and view all the answers

    A patient presents with a sore throat and a persistent cough. Which of the following is a possible cause of pharyngitis?

    <p>Gastroesophageal reflux disease</p> Signup and view all the answers

    What is the purpose of the modified Centor score in acute pharyngitis?

    <p>To determine the probability of streptococcal pharyngitis</p> Signup and view all the answers

    A patient presents with a sore throat and a history of smoking. Which of the following is a possible cause of pharyngitis?

    <p>Neoplasm</p> Signup and view all the answers

    What is the primary benefit of antibiotic therapy in acute pharyngitis?

    <p>To prevent complications</p> Signup and view all the answers

    A patient presents with a sore throat and a history of allergies. Which of the following is a possible cause of pharyngitis?

    <p>Allergies</p> Signup and view all the answers

    What is the primary difference between conductive and sensorineural hearing loss?

    <p>The location of hearing loss in the ear</p> Signup and view all the answers

    A patient presents with a sore throat and a history of recent travel. Which of the following is a possible cause of pharyngitis?

    <p>Neisseria gonorrhoeae</p> Signup and view all the answers

    What is the most likely type of hearing loss that Alex is experiencing?

    <p>Conductive hearing loss</p> Signup and view all the answers

    What structure separates the outer ear from the middle ear?

    <p>Tympanic membrane</p> Signup and view all the answers

    Which part of the ear is connected to the nasopharynx by the Eustachian tube?

    <p>Middle ear</p> Signup and view all the answers

    What is the primary function of the ossicles in the middle ear?

    <p>To transmit sound waves from the eardrum to the inner ear</p> Signup and view all the answers

    Which type of hearing loss is caused by dysfunction in the auditory pathway between the inner ear and auditory cortex?

    <p>Sensorineural hearing loss</p> Signup and view all the answers

    What is the term for the hole that connects the middle ear with the inner ear?

    <p>Oval window</p> Signup and view all the answers

    Study Notes

    Week 2: Clinical Medicine

    Pharyngitis

    • Pharyngitis is the inflammation of the pharynx
    • Duration:
      • Acute pharyngitis: less than 2 weeks
      • Chronic pharyngitis: more than 2 weeks
    • General approach to acute pharyngitis:
      • Rule out serious diagnoses and red flags/alarm symptoms
      • Determine the specific infectious cause (viral or bacterial)
      • Identify acute sore throat caused by group A beta-hemolytic streptococcal (GABHS) pharyngitis

    Causes of Pharyngitis

    • Infectious causes:
      • Viral: rhinovirus, coronavirus, adenovirus, parainfluenza virus, influenza A and B, herpes simplex virus (HSV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), human herpesvirus (HHV) 6, HIV
      • Bacterial: group A beta-hemolytic streptococci (GABHS), Fusobacterium necrophorum, group C beta-hemolytic streptococci, Neisseria gonorrhoeae, Corynebacterium diphtheriae, Mycoplasma pneumoniae, Chlamydophila pneumoniae
    • Non-infectious causes:
      • Allergies
      • Smoking
      • Gastroesophageal reflux disease (GERD)
      • Acute thyroiditis
      • Neoplasm

    Alarm Symptoms

    • Associated with pharyngitis:
      • Fever
      • Rash
      • Diffuse adenopathy
      • Sore throat
      • Weight loss
      • Night sweats
    • Associated with cough:
      • Hemoptysis
      • Chest pain
      • Dyspnea
      • Wheezing
      • Fever

    Modified Centor Score

    • Used to determine the probability of streptococcal pharyngitis
    • Online calculator available

    Viral Pharyngitis

    • Most pharyngitis cases are viral in origin
    • Associated symptoms:
      • Cough
      • Nasal congestion
      • Conjunctivitis
      • Hoarseness
      • Diarrhea
      • Oropharyngeal lesions (ulcers or vesicles)
    • Viral causes of pharyngitis do not require antibiotic therapy unless there is a secondary bacterial infection

    Common Cold vs. Influenza

    • Common cold:
      • Viral infection of the upper respiratory tract
      • Peaks in winter months
      • Symptoms usually worst 2-3 days then resolve in 7-10 days
      • Cough may last 2-3 weeks
      • Can be caused by many viruses, including rhinoviruses, coronaviruses, adenoviruses, and parainfluenza viruses
    • Influenza:
      • Viral infection of the upper and lower respiratory tract
      • Peaks in winter months
      • Symptoms usually worst 2-3 days then resolve in 7-10 days
      • Cough may last 2-3 weeks
      • Caused by Influenza A and B viruses

    Conductive and Sensorineural Hearing Loss

    • Conductive hearing loss:
      • Weber test: lateralization to affected ear
      • Rinne test: bone conduction > air conduction
    • Sensorineural hearing loss:
      • Weber test: lateralization to unaffected ear
      • Rinne test: air conduction > bone conduction

    Otitis Externa

    • Inflammation or infection of the external ear canal
    • Most commonly a bacterial infection (Pseudomonas species or Staphylococcus aureus)
    • Can be a fungal infection

    Learning Outcomes

    • Differentiate between chronic and acute pharyngitis
    • Differentiate between infectious and non-infectious causes of pharyngitis
    • Follow a systematic approach to the diagnosis of acute pharyngitis
    • Identify alarm symptoms associated with acute pharyngitis and cough
    • Apply the modified Centor score to patient cases
    • Know the relative frequencies of the causes of acute pharyngitis and how they vary based on patients’ epidemiological characteristics

    Pharyngitis

    • Pharyngitis refers to inflammation of the pharynx
    • Acute pharyngitis: duration less than 2 weeks
    • Chronic pharyngitis: duration more than 2 weeks

    Causes of Pharyngitis

    • Infectious causes:
      • Viral: rhinovirus, coronavirus, adenovirus, herpes simplex virus, influenza A and B, parainfluenza virus, Epstein-Barr virus, cytomegalovirus, human herpesvirus (HHV) 6, HIV
      • Bacterial: group A beta-hemolytic streptococci, Fusobacterium necrophorum, group C beta-hemolytic streptococci, Neisseria gonorrhoeae, Corynebacterium diphtheriae, Mycoplasma pneumoniae, Chlamydophila pneumoniae
    • Non-infectious causes:
      • Allergies
      • Smoking
      • Gastroesophageal reflux disease
      • Acute thyroiditis
      • Neoplasm

    Alarm Symptoms Associated with Acute Pharyngitis

    • Sore throat, dysphagia, or odynophagia
    • Drooling
    • Respiratory distress
    • Inability to open mouth fully (trismus)
    • Muffled voice
    • Stiff neck
    • Erythema of neck
    • Alarm symptoms associated with cough: productive cough, sneezing, runny nose, ear fullness

    Case of Alex Best

    • 15-year-old adolescent
    • CC: recent onset sore throat
    • Associated symptoms: productive cough, sneezing, runny nose, ear fullness, slight fatigue, muscle aches, headache
    • Physical exam findings: posterior oropharynx mildly inflamed and erythematous; no exudate present, posterior cervical nodes are enlarged and tender to palpation, nasal turbinates are red and swollen
    • Diagnosis: common cold
    • Whisper test: unable to repeat words whispered to the left ear
    • Hearing loss: conductive or sensorineural?

    Types of Hearing Loss

    • Conductive Hearing Loss: due to dysfunction in one or more parts of auditory pathway from external ear to middle ear
    • Sensorineural Hearing Loss: due to dysfunction in one or more parts of auditory pathway between inner ear and auditory cortex

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    Description

    Assess your knowledge on diagnosing pharyngitis, including differentiating between chronic and acute pharyngitis, identifying alarm symptoms, and applying the modified Centor score. This quiz is based on week 2 of the CMS150 Clinical Medicine course.

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