Clinical Biochemistry: Stomach Functions

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5 Questions

What is the function of the stomach component known as ECL?

Stimulate gastric secretion and histamine release

Which is the most potent stimulus for acid secretion by parietal cells in the stomach?

Stimulation of gastric secretion and histamine release

What is the cause of abnormal gastric residuum volume (>100-120 ml) after a night fast?

Hypersecretion of gastric juice

Which cells are responsible for the activation of pepsinogen in the stomach?

Chief cells

What is the main function of K dependent ATPase enzyme in the stomach?

Transport hydrogen against concentration gradient

Study Notes

Stomach Components and Functions

  • ECL (Enterochromaffin-like) cells produce histamine, which stimulates acid secretion by parietal cells.

Gastric Acid Secretion

  • The most potent stimulus for acid secretion by parietal cells is histamine.

Gastric Residuum Volume

  • Abnormal gastric residuum volume (>100-120 ml) after a night's fast is caused by gastric stasis or obstruction.

Pepsinogen Activation

  • Chief cells are responsible for the activation of pepsinogen in the stomach.

K-Dependent ATPase Enzyme

  • The main function of K-dependent ATPase enzyme in the stomach is to help pump H+ ions into the stomach lumen, thereby maintaining the acidic pH.

Test your knowledge on the components and functions of the stomach in clinical biochemistry. This quiz covers topics such as protein denaturation, activation of pepsinogen, iron absorption, and gastric secretion volume.

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