Clinical Biochemistry: Liver Physical Characteristics
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Questions and Answers

What are the physical characteristics of the liver?

  • Heaviest organ in the body with a weight range of 2 to 2.5 kg.
  • Weighs around 1.6 kg in both males and females.
  • Weighs about 150 g at birth and 1.2 to 1.8 kg in adults. (correct)
  • Largest organ in the body with a fixed weight of 1.5 kg.

    • How does the position of the liver change within the body?

  • Rotates during respiration and moves up and down with the diaphragm. (correct)
  • The liver remains static within the body.
  • Shifts upward from the lower abdomen towards the chest cavity.
  • Moves horizontally from left to right during respiration.

    • What are liver lobules composed of?

  • Hexagonal structures consisting of nerve cells.
  • Hexagonal structures consisting of hepatocytes. (correct)
  • Hexagonal structures surrounded by adipose tissue.
  • Circular structures made of muscle tissue.

    • Where does all blood flow from the intestine and pancreas reach before dispersion throughout the body?

    <p>Liver</p> Signup and view all the answers

    What is the role of the liver in the body's functions?

    <p>Liver is involved in diverse body functions and is multifunctional.</p> Signup and view all the answers

    What can be said about the liver's vital importance?

    <p>It is important in metabolism and eliminating toxic substances.</p> Signup and view all the answers

    Which function of the liver involves the formation of blood, particularly in embryos?

    <p>Hematological and synthetic functions</p> Signup and view all the answers

    What is one of the functions of the Kupffer cells in the liver related to detoxification?

    <p>Phagocytosis to eliminate foreign compounds</p> Signup and view all the answers

    Which mineral is actively involved in liver metabolism according to the text?

    <p>Iron</p> Signup and view all the answers

    Which serum enzyme from the liver can serve as a marker of liver damage?

    <p>Liver enzymes</p> Signup and view all the answers

    Which vitamin is stored in the liver according to the text?

    <p>Vitamin D</p> Signup and view all the answers

    Apart from urea, what is another compound mentioned in the text that undergoes detoxification in the liver?

    <p>Ammonia</p> Signup and view all the answers

    Which category of liver function tests checks the liver's capacity to transport organic anions and metabolize drugs?

    <p>Serum bilirubin</p> Signup and view all the answers

    What is a limitation of Liver Function Tests (LFTs) according to the passage?

    <p>They may lack sensitivity and specificity.</p> Signup and view all the answers

    Which of the following is a test that detects injury to hepatocytes?

    <p>Aminotransferases</p> Signup and view all the answers

    What is the role of bilirubin in the liver?

    <p>Derived from hemoglobin degradation</p> Signup and view all the answers

    In which liver diseases might Liver Function Tests (LFTs) be normal as mentioned in the text?

    <p>Cirrhosis</p> Signup and view all the answers

    What may cause decreased serum albumin levels according to the text?

    <p>Chronic disease</p> Signup and view all the answers

    What is the generally accepted reference range for normal plasma bilirubin concentrations in healthy individuals?

    <p>1.7 to 17.1 mmol/L</p> Signup and view all the answers

    What happens if the levels of bilirubin rise too high in neonates?

    <p>Permanent brain damage can occur</p> Signup and view all the answers

    Which coloration occurs due to the presence of bilirubin metabolites?

    <p>Orange coloration</p> Signup and view all the answers

    What is the function of unconjugated bilirubin in plasma?

    <p>It is neurotoxic</p> Signup and view all the answers

    In what condition is unconjugated hyperbilirubinemia commonly encountered?

    <p>Hemolysis</p> Signup and view all the answers

    Which condition leads to urine having a deep orange color due to high levels of conjugated bilirubin?

    <p>Obstruction in the biliary system</p> Signup and view all the answers

    What does the presence of urine bilirubin indicate?

    <p>Hepatobiliary disease</p> Signup and view all the answers

    Why is unconjugated bilirubin not normally found in urine?

    <p>It is bound to albumin and not filtered by the glomerulus</p> Signup and view all the answers

    When might conjugated bilirubin be found in urine despite normal serum levels?

    <p>Acute viral hepatitis</p> Signup and view all the answers

    What can tests strips impregnated with diazo reagent detect?

    <p>Low levels of bilirubin in urine</p> Signup and view all the answers

    What is a sensitive indicator of hepatocellular dysfunction?

    <p>Increased urobilinogen in urine</p> Signup and view all the answers

    In which condition is urobilinogen markedly increased?

    <p>Hemolysis</p> Signup and view all the answers

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