Clinical Biochemistry: Liver Physical Characteristics
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Questions and Answers

What are the physical characteristics of the liver?

  • Heaviest organ in the body with a weight range of 2 to 2.5 kg.
  • Weighs around 1.6 kg in both males and females.
  • Weighs about 150 g at birth and 1.2 to 1.8 kg in adults. (correct)
  • Largest organ in the body with a fixed weight of 1.5 kg.

How does the position of the liver change within the body?

  • Rotates during respiration and moves up and down with the diaphragm. (correct)
  • The liver remains static within the body.
  • Shifts upward from the lower abdomen towards the chest cavity.
  • Moves horizontally from left to right during respiration.

What are liver lobules composed of?

  • Hexagonal structures consisting of nerve cells.
  • Hexagonal structures consisting of hepatocytes. (correct)
  • Hexagonal structures surrounded by adipose tissue.
  • Circular structures made of muscle tissue.

Where does all blood flow from the intestine and pancreas reach before dispersion throughout the body?

<p>Liver (D)</p> Signup and view all the answers

What is the role of the liver in the body's functions?

<p>Liver is involved in diverse body functions and is multifunctional. (A)</p> Signup and view all the answers

What can be said about the liver's vital importance?

<p>It is important in metabolism and eliminating toxic substances. (C)</p> Signup and view all the answers

Which function of the liver involves the formation of blood, particularly in embryos?

<p>Hematological and synthetic functions (A)</p> Signup and view all the answers

What is one of the functions of the Kupffer cells in the liver related to detoxification?

<p>Phagocytosis to eliminate foreign compounds (D)</p> Signup and view all the answers

Which mineral is actively involved in liver metabolism according to the text?

<p>Iron (B)</p> Signup and view all the answers

Which serum enzyme from the liver can serve as a marker of liver damage?

<p>Liver enzymes (A)</p> Signup and view all the answers

Which vitamin is stored in the liver according to the text?

<p>Vitamin D (D)</p> Signup and view all the answers

Apart from urea, what is another compound mentioned in the text that undergoes detoxification in the liver?

<p>Ammonia (D)</p> Signup and view all the answers

Which category of liver function tests checks the liver's capacity to transport organic anions and metabolize drugs?

<p>Serum bilirubin (A)</p> Signup and view all the answers

What is a limitation of Liver Function Tests (LFTs) according to the passage?

<p>They may lack sensitivity and specificity. (C)</p> Signup and view all the answers

Which of the following is a test that detects injury to hepatocytes?

<p>Aminotransferases (A)</p> Signup and view all the answers

What is the role of bilirubin in the liver?

<p>Derived from hemoglobin degradation (C)</p> Signup and view all the answers

In which liver diseases might Liver Function Tests (LFTs) be normal as mentioned in the text?

<p>Cirrhosis (D)</p> Signup and view all the answers

What may cause decreased serum albumin levels according to the text?

<p>Chronic disease (B)</p> Signup and view all the answers

What is the generally accepted reference range for normal plasma bilirubin concentrations in healthy individuals?

<p>1.7 to 17.1 mmol/L (D)</p> Signup and view all the answers

What happens if the levels of bilirubin rise too high in neonates?

<p>Permanent brain damage can occur (B)</p> Signup and view all the answers

Which coloration occurs due to the presence of bilirubin metabolites?

<p>Orange coloration (D)</p> Signup and view all the answers

What is the function of unconjugated bilirubin in plasma?

<p>It is neurotoxic (B)</p> Signup and view all the answers

In what condition is unconjugated hyperbilirubinemia commonly encountered?

<p>Hemolysis (D)</p> Signup and view all the answers

Which condition leads to urine having a deep orange color due to high levels of conjugated bilirubin?

<p>Obstruction in the biliary system (B)</p> Signup and view all the answers

What does the presence of urine bilirubin indicate?

<p>Hepatobiliary disease (A)</p> Signup and view all the answers

Why is unconjugated bilirubin not normally found in urine?

<p>It is bound to albumin and not filtered by the glomerulus (D)</p> Signup and view all the answers

When might conjugated bilirubin be found in urine despite normal serum levels?

<p>Acute viral hepatitis (D)</p> Signup and view all the answers

What can tests strips impregnated with diazo reagent detect?

<p>Low levels of bilirubin in urine (A)</p> Signup and view all the answers

What is a sensitive indicator of hepatocellular dysfunction?

<p>Increased urobilinogen in urine (C)</p> Signup and view all the answers

In which condition is urobilinogen markedly increased?

<p>Hemolysis (D)</p> Signup and view all the answers

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