30 Questions
What are the physical characteristics of the liver?
Weighs about 150 g at birth and 1.2 to 1.8 kg in adults.
How does the position of the liver change within the body?
Rotates during respiration and moves up and down with the diaphragm.
What are liver lobules composed of?
Hexagonal structures consisting of hepatocytes.
Where does all blood flow from the intestine and pancreas reach before dispersion throughout the body?
Liver
What is the role of the liver in the body's functions?
Liver is involved in diverse body functions and is multifunctional.
What can be said about the liver's vital importance?
It is important in metabolism and eliminating toxic substances.
Which function of the liver involves the formation of blood, particularly in embryos?
Hematological and synthetic functions
What is one of the functions of the Kupffer cells in the liver related to detoxification?
Phagocytosis to eliminate foreign compounds
Which mineral is actively involved in liver metabolism according to the text?
Iron
Which serum enzyme from the liver can serve as a marker of liver damage?
Liver enzymes
Which vitamin is stored in the liver according to the text?
Vitamin D
Apart from urea, what is another compound mentioned in the text that undergoes detoxification in the liver?
Ammonia
Which category of liver function tests checks the liver's capacity to transport organic anions and metabolize drugs?
Serum bilirubin
What is a limitation of Liver Function Tests (LFTs) according to the passage?
They may lack sensitivity and specificity.
Which of the following is a test that detects injury to hepatocytes?
Aminotransferases
What is the role of bilirubin in the liver?
Derived from hemoglobin degradation
In which liver diseases might Liver Function Tests (LFTs) be normal as mentioned in the text?
Cirrhosis
What may cause decreased serum albumin levels according to the text?
Chronic disease
What is the generally accepted reference range for normal plasma bilirubin concentrations in healthy individuals?
1.7 to 17.1 mmol/L
What happens if the levels of bilirubin rise too high in neonates?
Permanent brain damage can occur
Which coloration occurs due to the presence of bilirubin metabolites?
Orange coloration
What is the function of unconjugated bilirubin in plasma?
It is neurotoxic
In what condition is unconjugated hyperbilirubinemia commonly encountered?
Hemolysis
Which condition leads to urine having a deep orange color due to high levels of conjugated bilirubin?
Obstruction in the biliary system
What does the presence of urine bilirubin indicate?
Hepatobiliary disease
Why is unconjugated bilirubin not normally found in urine?
It is bound to albumin and not filtered by the glomerulus
When might conjugated bilirubin be found in urine despite normal serum levels?
Acute viral hepatitis
What can tests strips impregnated with diazo reagent detect?
Low levels of bilirubin in urine
What is a sensitive indicator of hepatocellular dysfunction?
Increased urobilinogen in urine
In which condition is urobilinogen markedly increased?
Hemolysis
Explore the physical characteristics of the liver in clinical biochemistry. Learn about its importance in metabolism, detoxication, and elimination of toxic substances.
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