Clinical Biochemistry: Enzymes Overview
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Questions and Answers

What is the role of enzymes in the body?

  • They slow down reactions
  • They decrease the rate of reactions
  • They increase the rate of reactions without being changed in the overall process (correct)
  • They change the reactants into useless pathways

How are enzymes assigned names?

  • They are given three names: a short name, a systematic name, and a trivial name
  • They are assigned two names: a short recommended name and a systematic name (correct)
  • They are given only one name
  • They are not assigned names

What is the suffix commonly used in enzyme names?

  • -asein
  • -zyme
  • -ase (correct)
  • -inase

Why are systematic names used?

<p>To identify enzymes without ambiguity (A)</p> Signup and view all the answers

How are enzymes classified in the systematic naming system?

<p>Into six major classes with numerous subgroups (B)</p> Signup and view all the answers

What is a characteristic of some enzymes that retain their original trivial names?

<p>They do not give a hint of the associated enzymatic reaction (B)</p> Signup and view all the answers

What is the term for the active enzyme with its nonprotein component?

<p>Holoenzyme (C)</p> Signup and view all the answers

What type of molecules can bind to enzymes and increase their activity?

<p>Either metal ions or small organic molecules (A)</p> Signup and view all the answers

What is the purpose of localizing enzymes in specific organelles within the cell?

<p>To isolate the reaction substrate or product from other competing reactions (A)</p> Signup and view all the answers

What is the role of a catalyst in a chemical reaction?

<p>To accelerate the reaction (A)</p> Signup and view all the answers

What is the theory that explains the action of a catalyst?

<p>Transition state theory (C)</p> Signup and view all the answers

What is the term for a coenzyme that only transiently associates with the enzyme?

<p>Cosubstrate (D)</p> Signup and view all the answers

What is the suffix attached to a description of the chemical reaction catalyzed by an enzyme?

<p>-ase (B)</p> Signup and view all the answers

What is the role of the active site in an enzyme molecule?

<p>To bind the substrate and participate in catalysis (D)</p> Signup and view all the answers

What is the result of the binding of the substrate to the enzyme?

<p>A conformational change in the enzyme (D)</p> Signup and view all the answers

How much faster do enzyme-catalyzed reactions proceed compared to uncatalyzed reactions?

<p>103–108 times faster (B)</p> Signup and view all the answers

What is the turnover number of an enzyme?

<p>The number of molecules of substrate converted to product per enzyme molecule per second (B)</p> Signup and view all the answers

What is a characteristic of enzymes in terms of their specificity?

<p>They interact with one or a few substrates and catalyze only one type of chemical reaction (D)</p> Signup and view all the answers

What is the typical pH range at which most enzymes function?

<p>Between 6 and 8 (C)</p> Signup and view all the answers

What happens to the enzyme activity when the product concentration increases?

<p>The enzyme activity decreases (B)</p> Signup and view all the answers

What is the effect of ultraviolet radiation on certain enzymes?

<p>It inactivates the enzyme (A)</p> Signup and view all the answers

What does a low Km value indicate about an enzyme's substrate affinity?

<p>A strong substrate affinity (D)</p> Signup and view all the answers

At which pH does the enzyme pepsin function best?

<p>pH 2 (B)</p> Signup and view all the answers

What is the effect of extreme pH on enzyme activity?

<p>The enzyme becomes totally inactive (A)</p> Signup and view all the answers

What is the term for the energy required to convert a substance from its ground state to its transition state?

<p>Activation energy (C)</p> Signup and view all the answers

How does the rate of an enzyme-catalyzed reaction change when the concentration of enzyme is increased?

<p>It increases (C)</p> Signup and view all the answers

What happens to the velocity of an enzyme reaction when the temperature is increased?

<p>It increases up to a maximum, then declines (D)</p> Signup and view all the answers

What is the optimum temperature range for most enzymes?

<p>35°C–40°C (D)</p> Signup and view all the answers

Why do some enzymes, like Taq DNA polymerase, remain active at high temperatures?

<p>Due to their highly stable structure (A)</p> Signup and view all the answers

What is the term for the increase in enzyme velocity when the temperature is increased by 10°C?

<p>Q10 (B)</p> Signup and view all the answers

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