Clindamycin Flashcards
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Questions and Answers

What is the generic name of Clindamycin?

  • Clindamycin hydrochloride
  • Clindamycin palmitate hydrochloride
  • Clindamycin phosphate
  • All of the above (correct)
  • Which of the following is a trade name for Clindamycin?

  • Cleocin Hcl (correct)
  • Anitbiotic
  • Dalacin C (correct)
  • Clindamycin hydrochloride
  • What classification does Clindamycin belong to?

    Antibiotic

    Clindamycin hydrochloride is available in capsules of ___ mg.

    <p>75mg, 150mg, 300mg</p> Signup and view all the answers

    What is the mechanism of action for Clindamycin?

    <p>Inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome.</p> Signup and view all the answers

    What infections is Clindamycin used to treat?

    <p>Infections caused by sensitive staphylococci, streptococci, pneumococci, bacteroides, fusobacterium, clostridium, perfringes, and other sensitive aerobic and anaerobic organisms.</p> Signup and view all the answers

    Clindamycin can be used safely in all patients without any contraindications.

    <p>False</p> Signup and view all the answers

    What are some adverse effects of Clindamycin?

    <p>Headache, pharyngitis, abdominal pain, bloody diarrhea, colitis, constipation, GI upset, dermatitis, rash.</p> Signup and view all the answers

    What should be monitored in patients receiving Clindamycin?

    <p>Renal, hepatic, and hematopoietic function.</p> Signup and view all the answers

    Study Notes

    Clindamycin Overview

    • Clindamycin is an antibiotic available in different formulations including hydrochloride, palmitate hydrochloride, and phosphate.

    Trade Names

    • Commonly known as Cleocin Hcl, Dalacin C, and Cleocin Pediatric.

    Classification

    • Classified as an antibiotic, effective in treating various bacterial infections.

    Dosage Forms

    • Clindamycin hydrochloride: Available in capsules of 75mg, 150mg, and 300mg.
    • Clindamycin palmitate hydrochloride: Offered as granules for oral solution at 75mg/5ml.
    • Clindamycin phosphate: Available in injectable infusions in D5W (300mg/50ml, 600mg/50ml, 900mg/50ml) and multiple injection forms (150mg base/ml, 300mg base/2ml, 600mg base/4ml, 900mg base/6ml).

    Mechanism of Action

    • Works by inhibiting bacterial protein synthesis through binding to the 50S subunit of the ribosome.

    Indications

    • Effective against infections caused by sensitive staphylococci, streptococci, pneumococci, and a range of anaerobic and aerobic organisms.
    • Also used in the treatment of pelvic inflammatory disease.

    Contraindications

    • Not recommended for patients hypersensitive to clindamycin or lincomycin.
    • Risk of overgrowth of non-susceptible organisms such as yeasts; monitor for signs of superinfection.
    • Use cautiously in neonates and individuals with renal or hepatic impairment, asthma, or a history of gastrointestinal disease.

    Adverse Effects

    • Potential side effects include headache, pharyngitis, abdominal pain, bloody diarrhea, colitis, constipation, gastrointestinal upset, skin dryness, redness, burning, contact dermatitis, irritation, and rash.

    Nursing Implications

    • IM injections may elevate creatine kinase levels due to muscle irritation.
    • Continuous monitoring of renal, hepatic, and hematopoietic function is necessary.
    • Avoid using opioid antidiarrheals for drug-induced diarrhea, as they may worsen the condition.

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    Description

    Test your knowledge about Clindamycin with this set of flashcards. Learn about its generic and trade names, classification, and availability. Perfect for pharmacy students or anyone interested in antibiotics.

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