18 Questions
Which of the following is NOT a therapeutic use of beta-blockers?
Hyperthyroidism
What is the primary reason for the ultrashort duration of action of esmolol?
It undergoes extensive hydrolysis by plasma esterases.
Which of the following statements about pindolol is correct?
It is a partial agonist at beta-adrenergic receptors.
Which of the following statements about the use of beta-blockers in hypertrophic obstructive cardiomyopathy is correct?
Beta-blockers decrease heart rate and contractility, reducing outflow resistance.
What is the mechanism by which propranolol manages symptoms of hyperthyroidism?
It decreases tachycardia, anxiety, and tremors due to sympathetic overactivity.
Which of the following statements accurately describes the classification of beta-receptor blockers?
Nonselective beta-blockers block both beta-1 and beta-2 receptors, while selective beta-blockers block only beta-1 receptors.
Which of the following statements about the use of esmolol in acute arrhythmias during surgery is correct?
Esmolol is given by intravenous infusion for acute arrhythmias during surgery.
Which of the following statements accurately describes the cardiovascular effects of beta-blockers?
Some beta-blockers can decrease blood pressure by blocking vascular alpha-1 receptors or inhibiting the synthesis of prostaglandins.
Which of the following statements accurately describes the respiratory effects of beta-blockers?
Both nonselective and selective beta-blockers can produce bronchospasm, even at high doses.
Which of the following statements accurately describes the effects of beta-blockers on the central nervous system?
Beta-blockers with good CNS penetration can produce antianxiety effects and sexual dysfunction, while those with limited CNS penetration have no CNS effects.
Which of the following statements accurately describes the metabolic effects of beta-blockers?
Beta-blockers increase plasma triglyceride levels and decrease HDL cholesterol levels.
Which of the following is a selective $\beta_1$ blocker?
Bisoprolol
Which of the following statements accurately describes the effects of beta-blockers on skeletal muscle?
Beta-blockers decrease essential tremors by blocking beta-2 receptors in skeletal muscle.
What is the mechanism of action of propranolol in the treatment of esophageal varices due to liver cirrhosis?
Propranolol reduces portal and hepatic blood flow by decreasing cardiac output and vascular compliance in the splanchnic vascular bed due to unopposed alpha-adrenergic action.
Which of the following is NOT a use of beta-blockers?
Treatment of bronchial asthma
Which of the following is a common adverse effect of beta-blockers?
Tiredness and fatigue
Which of the following is an absolute contraindication for the use of beta-blockers?
Peripheral vascular disease
What is the recommended management for sudden withdrawal of beta-blockers after prolonged use?
Gradual tapering of the dose over a few days
This quiz by Dr. Asmaa El-rakhawy covers the classification of β-receptor blockers, the pharmacological effects and uses of β blockers, as well as the adverse contraindications of β blockers. It also discusses the types of β blockers including nonselective, selective, those with good CNS penetration, with hepatic metabolism, limited CNS penetration, excreted mainly by kidney, and those with VD action.
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