Class V Anti-arrhythmic Agents Flashcards

Questions and Answers

What is this drug associated with this class? (Select all that apply)

Adenosine (correct)

Digoxin (correct)

Ibuprofen

Aspirin

What is the mechanism of action of adenosine?

Terminates PSVT by blocking SA and AV nodes

What is the use of adenosine?

Converts supraventricular tachycardia to normal sinus rhythm

What are the common adverse effects of adenosine?

Flushing of the face, shortness of breath, chest pressure, nausea, headache Signup and view all the answers

How is adenosine administered?

IV dosing 6mg, ministered by rapid bolus injection followed by saline flush. If effective, then use 12mg dose. Signup and view all the answers

What is the mechanism of action of digoxin?

Slows AV node induction, reduces conduction velocity and automaticity. Increases cardiac output. Signup and view all the answers

What is the common adverse effect of digoxin?

(N, V, D), loss of appetite, bradycardia, arrhythmias, dizziness, confusion, fatigue, blurred vision or yellow or green vision Signup and view all the answers

What are the serious adverse effects associated with digoxin?

Severe arrhythmias, severe bradycardia, central nervous effects Signup and view all the answers

What does digoxin treat?

Atrial fibrillation, atrial flutter, paroxysmal tachycardia Signup and view all the answers

Study Notes

Class V: Other Anti-arrhythmic Agents

Key drugs include adenosine and digoxin.

Mechanism of Action

Adenosine terminates paroxysmal supraventricular tachycardia (PSVT) by blocking signal conduction in the sinoatrial (SA) and atrioventricular (AV) nodes.
Digoxin slows AV node conduction, reducing conduction velocity and automaticity, while also increasing cardiac output.

Use of Adenosine

Adenosine is primarily used to convert supraventricular tachycardia to normal sinus rhythm.

Adverse Effects of Adenosine

Common side effects include flushing of the face, shortness of breath, chest pressure, nausea, and headache.

Administration of Adenosine

Administered intravenously at a dose of 6mg via rapid bolus injection (within 1 to 2 seconds), followed by a saline flush. If effective, a subsequent dose of 12mg may be given.

Adverse Effects of Digoxin

Common side effects include nausea, vomiting, diarrhea, loss of appetite, bradycardia, arrhythmias, dizziness, confusion, fatigue, and blurred or altered vision (yellow/green).

Serious Adverse Effects of Digoxin

Severe bradycardia and arrhythmias, along with central nervous system effects, may occur.

Indications for Digoxin

Digoxin is used to treat atrial fibrillation, atrial flutter, and paroxysmal tachycardia.

Description

Test your knowledge of Class V anti-arrhythmic agents with these flashcards. Learn about adenosine, its mechanism of action, uses, and side effects. Perfect for students and professionals in the medical field looking to reinforce their understanding of cardiology.