Podcast
Questions and Answers
What is the mechanism of action of Chloramphenicol?
What is the mechanism of action of Chloramphenicol?
- Interferes with cell wall synthesis
- Binds to the 30S ribosomal subunit
- Inhibits DNA synthesis in bacteria
- Inhibits protein synthesis in bacteria by binding to the 50S ribosomal subunit (correct)
Which antibiotic is most potent against anaerobes?
Which antibiotic is most potent against anaerobes?
- Chloramphenicol
- Erythromycin
- Clindamycin (correct)
- Lincomycin
What is the main adverse effect associated with Clindamycin use?
What is the main adverse effect associated with Clindamycin use?
- Hypersensitivity reactions
- Neutropenia (correct)
- Rashes
- Impaired liver function
Which antibiotic is known for causing antibiotic-associated colitis?
Which antibiotic is known for causing antibiotic-associated colitis?
What is the mechanism of action of quinolones?
What is the mechanism of action of quinolones?
Which antibiotic has bactericidal activity dependent on concentration and is useful against gram-positive infections?
Which antibiotic has bactericidal activity dependent on concentration and is useful against gram-positive infections?
Which antibiotic is known for having increased stability and oral bioavailability compared to Erythromycin?
Which antibiotic is known for having increased stability and oral bioavailability compared to Erythromycin?
Which antibiotic is effective against Borrelia burgdorferi and has a unique dosing regimen of once daily for 3 days?
Which antibiotic is effective against Borrelia burgdorferi and has a unique dosing regimen of once daily for 3 days?
Which antibiotic is a reversible inhibitor of the CYP3A4 enzyme and effective against macrolide-resistant Gram-positive bacteria?
Which antibiotic is a reversible inhibitor of the CYP3A4 enzyme and effective against macrolide-resistant Gram-positive bacteria?
Which antibiotic is associated with the side effects of nausea, vomiting, unpleasant taste, and gray baby syndrome?
Which antibiotic is associated with the side effects of nausea, vomiting, unpleasant taste, and gray baby syndrome?
Which antibiotic is derived from Streptomyces venezuelae, inhibits CYP450 enzymes, and may cause blood dyscrasias?
Which antibiotic is derived from Streptomyces venezuelae, inhibits CYP450 enzymes, and may cause blood dyscrasias?
Which antibiotic has a spectrum of activity that includes bactericidal effects against H.influenzae and M.meningitides?
Which antibiotic has a spectrum of activity that includes bactericidal effects against H.influenzae and M.meningitides?
What is the mechanism of action of aminoglycosides like kanamycin and gentamicin?
What is the mechanism of action of aminoglycosides like kanamycin and gentamicin?
Which aminoglycoside is a derivative of Kanamycin produced in Japan with the broadest spectrum of activity/toxicity?
Which aminoglycoside is a derivative of Kanamycin produced in Japan with the broadest spectrum of activity/toxicity?
What is the most common adverse drug reaction associated with aminoglycosides like Kanamycin and Gentamicin?
What is the most common adverse drug reaction associated with aminoglycosides like Kanamycin and Gentamicin?
What is a common untoward effect associated with tetracyclines like Doxycycline?
What is a common untoward effect associated with tetracyclines like Doxycycline?
What is the mode of action of erythromycin on bacterial cells?
What is the mode of action of erythromycin on bacterial cells?
Which antibiotic family contains agents known as 'Thromycins'?
Which antibiotic family contains agents known as 'Thromycins'?
What is the spectrum of activity for macrolides like Erythromycin?
What is the spectrum of activity for macrolides like Erythromycin?
What is one common adverse drug reaction associated with the use of chloramphenicol?
What is one common adverse drug reaction associated with the use of chloramphenicol?
Which of the following antibiotics is known for causing GI distress, hepatotoxicity, acute cholestatic hepatitis, fever, eosinophilia, and rashes?
Which of the following antibiotics is known for causing GI distress, hepatotoxicity, acute cholestatic hepatitis, fever, eosinophilia, and rashes?
Which antibiotic family includes agents that inhibit bacterial protein synthesis by binding to the 30s ribosomal subunit and blocking tRNA binding to the A site?
Which antibiotic family includes agents that inhibit bacterial protein synthesis by binding to the 30s ribosomal subunit and blocking tRNA binding to the A site?
