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Questions and Answers
What does the mnemonic 'So At Disco, Devil Sipped Down Five Drinks' represent?
What does the mnemonic 'So At Disco, Devil Sipped Down Five Drinks' represent?
- Steps in photosynthesis
- Enzymes of the Glycolysis pathway
- Hormones in the human body
- Enzymes of the Citric Acid Cycle (correct)
What enzyme corresponds to 'So' in the mnemonic?
What enzyme corresponds to 'So' in the mnemonic?
Citrate Synthase
What enzyme corresponds to 'At' in the mnemonic?
What enzyme corresponds to 'At' in the mnemonic?
Aconitase
What enzyme corresponds to 'Disco' in the mnemonic?
What enzyme corresponds to 'Disco' in the mnemonic?
What enzyme corresponds to 'Devil' in the mnemonic?
What enzyme corresponds to 'Devil' in the mnemonic?
What enzyme corresponds to 'Sipped' in the mnemonic?
What enzyme corresponds to 'Sipped' in the mnemonic?
What enzyme corresponds to 'Down' in the mnemonic?
What enzyme corresponds to 'Down' in the mnemonic?
What enzyme corresponds to 'Five' in the mnemonic?
What enzyme corresponds to 'Five' in the mnemonic?
What enzyme corresponds to 'Drinks' in the mnemonic?
What enzyme corresponds to 'Drinks' in the mnemonic?
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Study Notes
Citric Acid Cycle Enzymes
- Mnemonic to remember the order of the enzymes: "So At Disco, Devil Sipped Down Five Drinks."
Enzyme Details
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Citrate Synthase: The first enzyme in the citric acid cycle, catalyzes the synthesis of citrate from acetyl-CoA and oxaloacetate.
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Aconitase: The second enzyme, converts citrate into isocitrate through a two-step process involving cis-aconitate.
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Isocitrate Dehydrogenase: The third enzyme, oxidizes isocitrate to α-ketoglutarate while reducing NAD+ to NADH and releasing CO2.
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α-Ketoglutarate Dehydrogenase: The fourth enzyme, converts α-ketoglutarate to succinyl-CoA, also producing NADH and CO2.
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Succinyl-CoA Synthase: The fifth enzyme, catalyzes the conversion of succinyl-CoA to succinate, generating GTP or ATP.
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Succinic Dehydrogenase: The sixth enzyme, converts succinate to fumarate, reducing FAD to FADH2 in the process.
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Fumarase: The seventh enzyme, facilitates the hydration of fumarate to malate.
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Malate Dehydrogenase: The eighth enzyme, converts malate back to oxaloacetate, producing NADH and completing the cycle.
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