Circulatory System Overview
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Questions and Answers

What is the primary shape of red blood cells?

  • Flat discs
  • Biconcave disks (correct)
  • Spherical
  • Cylindrical
  • What is the key function of hemoglobin in red blood cells?

  • To bind and transport oxygen (correct)
  • To fight infections
  • To transport nutrients
  • To produce ATP
  • What color does oxyhemoglobin appear when bound to oxygen?

  • Deep blue
  • Bright red (correct)
  • Pale yellow
  • Dark brown
  • How is ATP generated in red blood cells?

    <p>Anaerobically without oxygen</p> Signup and view all the answers

    What physiological condition is indicated by a high total white blood cell count?

    <p>Leukocytosis</p> Signup and view all the answers

    Why is the flexible plasma membrane of red blood cells important?

    <p>To enable movement through capillaries</p> Signup and view all the answers

    What percentage is considered a normal total white blood cell count?

    <p>4500 - 11000 cells per microliter</p> Signup and view all the answers

    What occurs to hemoglobin when oxygen diffuses into body tissues?

    <p>It becomes deoxyhemoglobin</p> Signup and view all the answers

    What is the primary role of neutrophils in the immune system?

    <p>To phagocytize infectious pathogens and bacteria</p> Signup and view all the answers

    What distinguishes eosinophils from other white blood cells?

    <p>Their bi-lobed nucleus and reddish-pink staining granules</p> Signup and view all the answers

    Which type of white blood cell orchestrates the immune response against viral infections?

    <p>T-lymphocytes</p> Signup and view all the answers

    What is the function of basophils during inflammatory reactions?

    <p>To release histamine and heparin</p> Signup and view all the answers

    Which of the following white blood cells is typically the most abundant in a healthy individual?

    <p>Neutrophils</p> Signup and view all the answers

    What is the primary function of the thymus in the lymphatic system?

    <p>Maturation of T cells</p> Signup and view all the answers

    What is histamine's primary function in the immune response?

    <p>To increase the permeability of capillaries and cause vasodilation</p> Signup and view all the answers

    What percentage of white blood cells do lymphocytes typically constitute?

    <p>20-40%</p> Signup and view all the answers

    Which type of lymphatic tissue is described as the first layer of defense?

    <p>Tonsils</p> Signup and view all the answers

    What occurs to B-lymphocytes when they become activated?

    <p>They develop into plasma cells that produce antibodies</p> Signup and view all the answers

    What happens to the thymus size during childhood?

    <p>It increases in size</p> Signup and view all the answers

    What is the primary role of macrophages in the lymphatic system?

    <p>Phagocytizing old red blood cells and platelets</p> Signup and view all the answers

    Where are lymphocytes primarily found?

    <p>Mucosa-associated lymph tissue (MALT)</p> Signup and view all the answers

    The invaginated outer edges of tonsils form structures called:

    <p>Crypts</p> Signup and view all the answers

    Which statement regarding the thymus is correct?

    <p>It is involved in T cell maturation</p> Signup and view all the answers

    Which area does MALT primarily monitor for immune responses?

    <p>Walls of respiratory and gastrointestinal tracts</p> Signup and view all the answers

    What is the primary function of arteries?

    <p>Carry oxygenated blood away from the heart</p> Signup and view all the answers

    How does the tunica media contribute to the function of arteries?

    <p>By regulating blood flow and withstanding pressure</p> Signup and view all the answers

    Which statement accurately describes arterioles?

    <p>They are small branches of arteries that regulate blood flow</p> Signup and view all the answers

    What type of layer is present in capillaries and what is its function?

    <p>Single layer of endothelial cells to allow diffusion</p> Signup and view all the answers

    What distinguishes veins from arteries?

    <p>Veins have valves to prevent backflow</p> Signup and view all the answers

    What is the role of the tunica externa in veins?

    <p>Provide structural support and elasticity</p> Signup and view all the answers

    What is the main function of venules in the circulatory system?

    <p>Collect blood from capillaries and transport it to larger veins</p> Signup and view all the answers

    Which layer is absent in capillaries and why?

    <p>Tunica media, because they do not need to dilate</p> Signup and view all the answers

    What is the primary function of conducting arteries?

    <p>Withstand and reduce blood pressure fluctuations</p> Signup and view all the answers

    Which type of capillary is characterized by its many pores and is commonly found in endocrine glands?

    <p>Fenestrated capillary</p> Signup and view all the answers

    How do skeletal muscles and valves work together to promote venous circulation?

    <p>Push blood through the veins and prevent back flow</p> Signup and view all the answers

    When do new blood vessels typically form in an adult?

    <p>Throughout life</p> Signup and view all the answers

    What changes are commonly associated with aging in blood vessels?

    <p>Varicose veins and atherosclerosis</p> Signup and view all the answers

    What is the role of the precapillary sphincter in blood circulation?

    <p>Regulate blood flow into capillary beds</p> Signup and view all the answers

    What is the primary route of the systemic circulation?

    <p>Left heart to arteries to body tissues to veins to right heart</p> Signup and view all the answers

    What characterizes sinusoid capillaries?

    <p>Wide spaces and incomplete basement membranes</p> Signup and view all the answers

    What is the correct order of the cardiac conduction pathway?

    <p>Sinoatrial node, Atrioventricular node, Atrioventricular bundle, Purkinje fibers</p> Signup and view all the answers

    Which of the following represents the correct sequence of events in the cardiac cycle?

    <p>Atrial systole, early ventricular systole, late ventricular systole</p> Signup and view all the answers

    What is the primary germ cell layer from which the heart is derived?

    <p>Mesoderm</p> Signup and view all the answers

    What is the main difference between adult and fetal circulation?

    <p>Fetal circulation bypasses lungs and liver capillary beds</p> Signup and view all the answers

    During which phase does the ventricular pressure rise causing AV valves to close?

    <p>Early ventricular systole</p> Signup and view all the answers

    Which structure directs blood from the umbilical vein to the right atrium in fetal circulation?

    <p>Ductus venosus</p> Signup and view all the answers

    In which phase does the atrial pressure rise, causing the AV valves to open?

    <p>Late ventricular diastole</p> Signup and view all the answers

    What is the definition of systole in relation to heart chambers?

    <p>Contraction of a heart chamber</p> Signup and view all the answers

    Study Notes

    Circulatory System

    • The heart pumps blood, delivering oxygen and removing waste products.
    • Arteries carry oxygenated blood away from the heart; pulmonary arteries carry deoxygenated blood to the lungs.
    • Capillaries facilitate gas exchange.
    • Pulmonary veins carry oxygenated blood to the heart; systemic veins carry deoxygenated blood back to the heart.
    • The lungs perform gas exchange.

    Blood Functions

    • Transportation: Blood carries gases, hormones, nutrients, and waste products.
    • Protection: White blood cells (WBCs) and antibodies defend against pathogens; platelets and proteins are involved in clotting.
    • Regulation: Maintaining pH, fluid balance, and temperature.

    Bodily Fluids

    • Blood: Found throughout the body, consisting of plasma and formed elements (RBCs, WBCs, and platelets)
      • Plasma: fluid matrix (no cells).
      • Formed elements: 45% of total blood volume.
      • Buffy coat: Leukocytes and platelets (less than 1%).
      • Hematocrit: Percentage of volume of all formed elements (45%).
    • Plasma solutes: Ions, nutrients, gases, and waste (1%).
    • Interstitial fluid: Derived from plasma, found in capillaries.
    • Lymph: Found in lymph vessels, ground substance of blood without clotting proteins.
    • Serum: Interstitial fluid without clotting proteins.

    Blood Cell Types

    • Formed elements (Blood Cells):
      • RBCs (Red Blood Cells): 55% of whole blood. Biconcave disks, no nucleus, and very flexible plasma membrane.
        • Functions: Gas transportation (oxygen binding). ATP generation.
      • Hemoglobin (color red pigment with 4 heme groups): Each heme has iron binding oxygen, for oxygen transport. Oxygen loading (oxygen binding) occurs in the lungs.
      • Oxyhemoglobin: bright red, hemoglobin bonded with oxygen.
      • Deoxyhemoglobin: dark red, hemoglobin not bonded with oxygen
      • WBCs (White Blood Cells): Less than 1%.
      • Platelets: Less than 1%. Involved in blood clotting.
      • For neutrophil type: 50-70 %, phagocytize infectious pathogens, nucleus segmented and varied in 2-5 lobes, granules appear light purple.
      • For eosinophil type: 1-4 %, attack parasitic worms, phagocytize antigen-antibody complexes, bilobed nucleus, granules stain reddish-pink.
      • For basophil type: .5-1 %, release histamine and heparin during inflammatory or allergic reactions, bi-lobed nuclei, granules stain blue-violet, occlude nucleus and cytoplasm.
    • Others:
      • Lymphocytes (20-40%): Orchestrate immune responses, attack viruses/infected cells, produce antibodies (B cells), and natural killer cells.
      • Monocytes (2-8%): Exit blood vessels and become macrophages, phagocytize pathogens.

    Heart Anatomy and Function

    • Apex: Pointed end projecting inferolaterally.
    • Base: Superior portion where major vessels attach.
    • Fibrous pericardium: Surrounds the heart, fibrous sac lined with serous membrane, protects and anchors the heart, prevents blood from overflowing into the heart, provides friction-free environment.
    • Serous pericardium: Parietal layer lines the inside of fibrous pericardium, visceral layer covers external surface of heart.
    • Endocardium: Simple squamous epithelium and areolar connective tissue.
    • Atria: Right atrium receives deoxygenated blood from superior and inferior vena cava and right and left pulmonary veins. Left atrium receives oxygenated blood from the lungs.
    • Ventricles: Right ventricle pumps deoxygenated blood to the lungs, left ventricle pumps oxygenated blood to the body.

    Blood Vessels

    • Arteries: Carry oxygenated blood away from the heart, thick and muscular walls with smooth and elastic fibers to withstand high pressure, regulate blood flow. Tunica interna, tunica media, tunica externa.
    • Arterioles: Small branches of arteries that lead to capillaries, thinner layer allowing blood flow and able to control blood flow, pressure through contraction.
    • Capillaries: Sites of gas and nutrient exchange, single layer of endothelial cells.
    • Venules: Collect blood from capillaries and transport to veins. Thin layer similar to capillaries to provide support & Minimal construction.
    • Veins: Return deoxygenated blood to the heart, contain valves to prevent backflow, lower pressure than arteries, structural support and elasticity.

    Lymphatic System

    • Functions: Returns interstitial fluid to blood circulation; monitors interstitial fluid; mounts immune responses.
    • Lymphatic capillaries: Closed-end tubes that collect interstitial fluid, and lipids (chyle in intestinal tract).
    • Lymph nodes: Filter lymph; site of immune responses.

    Lung Anatomy and Functions

    • Respiratory Membrane: Alveolar simple squamous epithelial cells wall. Capillary endothelial walls.
    • Alveoli: Sites of gas exchange in the lungs. Surfactant to prevent sticking.
    • Pleura: Lining surrounding lungs to reduce friction. Parietal layer (thoracic wall); visceral layer (lung surface).

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    Description

    Explore the essential functions and components of the circulatory system, including the heart, blood vessels, and blood. This quiz covers how blood transports nutrients and waste, along with the roles of different blood cells and fluids in the body.

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