Circulatory Physiology Quiz

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Questions and Answers

Which of the following substances is primarily found in the blood and plays a significant role in maintaining osmotic pressure?

  • Albumin (correct)
  • Water
  • Urea
  • Glucose

What directly increases blood viscosity in the human body?

  • Increased body weight
  • Increased serum plasma volume
  • Increased hematocrit (correct)
  • Increased muscle mass

What type of junctions primarily exist between the endothelial cells of capillaries?

  • Tight junctions (correct)
  • Adherens junctions
  • Gap junctions
  • Desmosomes

Which of the following substances is NOT typically measured as a parameter of the blood’s perfusion capacity?

<p>Urea (B)</p> Signup and view all the answers

Which physiological process would be least affected by a change in serum plasma volume?

<p>Immune response capabilities (B)</p> Signup and view all the answers

Which substance acts as a natural anticoagulant in the bloodstream?

<p>Heparin (D)</p> Signup and view all the answers

What do fibrin fibers primarily contribute to during clotting?

<p>Stabilization of the blood clot (D)</p> Signup and view all the answers

Which of the following statements accurately describes the endothelial cell surface?

<p>It is smooth and minimizes friction. (B)</p> Signup and view all the answers

Which factor is essential for breaking down fibrin during the clot dissolution process?

<p>Plasmin (C)</p> Signup and view all the answers

In the context of the immune system, what typically constitutes the last line of defense against infection?

<p>Innate immune response (C)</p> Signup and view all the answers

Which nerve innervates the esophagus and is part of the vagus nerve system?

<p>Left vagus nerve (A), Right vagus nerve (D)</p> Signup and view all the answers

What is the primary responsibility of the right recurrent laryngeal nerve?

<p>To innervate the larynx for voice production (B)</p> Signup and view all the answers

Which nerve is associated with both voluntary and involuntary control of the organs within the thoracic cavity?

<p>Left vagus nerve (D)</p> Signup and view all the answers

In which anatomical region does the right recurrent laryngeal nerve take its path?

<p>Around the aortic arch (D)</p> Signup and view all the answers

What is a common clinical manifestation of damage to the recurrent laryngeal nerves?

<p>Hoarseness or loss of voice (B)</p> Signup and view all the answers

Which structure receives deoxygenated blood from the body?

<p>Right atrium (C)</p> Signup and view all the answers

What is the primary function of the left ventricle in the heart?

<p>Pumping oxygenated blood to the body (D)</p> Signup and view all the answers

Which structure separates the left atrium from the left ventricle?

<p>Mitral valve (A)</p> Signup and view all the answers

In which anatomical space would you find the apex of the heart?

<p>5th left intercostal space (D)</p> Signup and view all the answers

Which chamber of the heart has the thickest muscular wall?

<p>Left ventricle (B)</p> Signup and view all the answers

Which of the following antibodies is known for its pentameric structure?

<p>IgM (B)</p> Signup and view all the answers

Which artery does NOT arise from the internal thoracic artery?

<p>Intercostal artery (C)</p> Signup and view all the answers

What is the significance of the 2nd left intercostal space in a clinical examination?

<p>It is the site for cardiac auscultation. (D)</p> Signup and view all the answers

Which of these statements about intercostal spaces is true?

<p>Each intercostal space houses arteries and nerves. (A)</p> Signup and view all the answers

What structure is typically located in the 6th right intercostal space?

<p>None of the above (D)</p> Signup and view all the answers

What process does opsonization specifically refer to?

<p>A method for pathogens to be selected for phagocytosis and destruction (A)</p> Signup and view all the answers

Which cell type is NOT directly involved in the opsonization process?

<p>Erythrocytes (B)</p> Signup and view all the answers

How are pathogens targeted for destruction during opsonization?

<p>Through phagocyte interaction with surface antibodies (D)</p> Signup and view all the answers

What is the primary cellular response involved in inflammation that allows for the movement of immune cells?

<p>Squeezing through blood capillary pores (B)</p> Signup and view all the answers

In which form is the least amount of iron found in the human body?

<p>Transferrin (D)</p> Signup and view all the answers

Flashcards

Blood viscosity increase

Increased hematocrit directly increases blood's thickness (viscosity).

Blood components

Albumin, glucose, urea, and water are crucial components of blood.

Capillary junctions

Tight junctions mainly make up the junctions between endothelial cells in capillaries.

Location of tight junctions

Tight junctions primarily occur in capillaries.

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Hematocrit and viscosity

Higher hematocrit leads to increased blood viscosity.

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Reticulocyte

A type of immature red blood cell.

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Opsonization

Process tagging pathogens for phagocytosis.

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CFU-B

Colony-forming unit for B cells (Bone marrow).

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CFU-S

Colony-forming unit for stem cells.

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Proerythroblast

An early erythroid precursor cell.

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Smooth endothelial surface

The inner lining of blood vessels, composed of endothelial cells, has a smooth surface to minimize friction and allow blood to flow easily.

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Plasmin

An enzyme that dissolves fibrin clots, helping to break down blood clots and restore normal blood flow.

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Heparin

A natural anticoagulant that prevents blood clotting by inhibiting the formation of thrombin, a key enzyme in the clotting process.

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Fibrin fibers

Thread-like proteins that form a mesh-like network during blood clotting, trapping blood cells and forming a stable clot.

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Last line of defense against infection

This refers to the immune system, which acts as the final barrier against invading pathogens, mounting a specific and targeted response to eliminate infections.

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Esophagus

The muscular tube connecting the throat (pharynx) to the stomach, responsible for transporting food.

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Right Vagus Nerve

One of the two vagus nerves, it controls various body functions including heart rate, digestion, and respiratory rate. It's located on the right side of the body.

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Right Recurrent Laryngeal Nerve

A branch of the right vagus nerve that loops under the right subclavian artery before ascending to the larynx, responsible for voice production.

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Left Vagus Nerve

One of the two vagus nerves, it controls various body functions including heart rate, digestion, and respiratory rate. It's located on the left side of the body.

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Vertebral canal

The hollow space within the vertebral column, which encloses and protects the spinal cord.

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Right atrium

The upper chamber of the heart on the right side, receiving deoxygenated blood from the body.

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Right ventricle

The lower chamber of the heart on the right side, pumping deoxygenated blood to the lungs.

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Left atrium

The upper chamber of the heart on the left side, receiving oxygenated blood from the lungs.

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Left ventricle

The lower chamber of the heart on the left side, pumping oxygenated blood to the body.

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Pentamere structure

A protein structure with five identical subunits arranged together.

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Internal thoracic artery branches

The internal thoracic artery supplies blood to the chest wall and gives rise to several important branches, including the anterior intercostal arteries, the musculophrenic artery, and the superior epigastric artery.

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Anterior intercostal arteries

These arteries arise from the internal thoracic artery and supply blood to the intercostal spaces, which are the spaces between the ribs.

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Musculophrenic artery

A branch of the internal thoracic artery that continues towards the diaphragm, supplying blood to the diaphragm and the muscles of the abdominal wall.

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Superior epigastric artery

Another branch of the internal thoracic artery that descends into the abdomen, supplying blood to the upper abdominal wall structures.

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Pericardium

A sac-like structure that encloses the heart, providing protection and lubrication.

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Study Notes

Circulatory Physiology

  • Arteries transport blood under high pressure to tissues.
  • Veins collect blood from capillaries, merging into larger veins.
  • Capillary hydrostatic pressure forces fluid & dissolved substances into interstitial spaces.
  • Approximate average net filtration pressure of capillaries is about 20 mmHg.
  • Arterioles are the smallest arterial branches, controlling blood flow.

Blood Flow in Circulation

  • Overall blood flow in adult rest is about 5000 ml/min.
  • Albumin has less permeability compared to other molecules like glucose and water.
  • Increasing hematocrit directly increases blood viscosity.
  • Tight junctions are found between capillary endothelial cells in the kidney, spleen, liver, and brain.

Blood Reservoirs and Blood Flow Rate

  • Edema in legs may be a symptom in people standing long periods with varicose veins.
  • Rate of blood flow through the entire circulatory system equals cardiac output.
  • Inhibition of sympathetic activity dilates blood vessels and increase blood flow.
  • In aortic valve stenosis, aortic pressure pulse is significantly decreased.

Colloid Osmotic Pressure

  • Albumin plays a significant role in colloid osmotic pressure.
  • The aortic arc baroreceptors send signals to the vasomotor center through the vagus and glossopharyngeal nerves.

Hematocrit

  • Hematocrit is elevated above normal range in polycythemia.
  • The brain's vasomotor center controls vasoconstriction.

Blood Flow, Blood Pressure, and other factors

  • Based on Ohm's law, higher pressure difference leads to increased blood flow.

Blood Cells and Components

  • Proerythroblast is the first cell identified in the RBC series.
  • Opsonization involves a process where pathogens are marked for phagocytosis.
  • Iron in the human body is minimally present as ferritin.
  • Leukemic cells often show metastatic growth in abnormal body areas.

Blood Clotting

  • Thrombin does not directly affect factor VI.

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