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Questions and Answers
Which of the following substances is primarily found in the blood and plays a significant role in maintaining osmotic pressure?
Which of the following substances is primarily found in the blood and plays a significant role in maintaining osmotic pressure?
- Albumin (correct)
- Water
- Urea
- Glucose
What directly increases blood viscosity in the human body?
What directly increases blood viscosity in the human body?
- Increased body weight
- Increased serum plasma volume
- Increased hematocrit (correct)
- Increased muscle mass
What type of junctions primarily exist between the endothelial cells of capillaries?
What type of junctions primarily exist between the endothelial cells of capillaries?
- Tight junctions (correct)
- Adherens junctions
- Gap junctions
- Desmosomes
Which of the following substances is NOT typically measured as a parameter of the blood’s perfusion capacity?
Which of the following substances is NOT typically measured as a parameter of the blood’s perfusion capacity?
Which physiological process would be least affected by a change in serum plasma volume?
Which physiological process would be least affected by a change in serum plasma volume?
Which substance acts as a natural anticoagulant in the bloodstream?
Which substance acts as a natural anticoagulant in the bloodstream?
What do fibrin fibers primarily contribute to during clotting?
What do fibrin fibers primarily contribute to during clotting?
Which of the following statements accurately describes the endothelial cell surface?
Which of the following statements accurately describes the endothelial cell surface?
Which factor is essential for breaking down fibrin during the clot dissolution process?
Which factor is essential for breaking down fibrin during the clot dissolution process?
In the context of the immune system, what typically constitutes the last line of defense against infection?
In the context of the immune system, what typically constitutes the last line of defense against infection?
Which nerve innervates the esophagus and is part of the vagus nerve system?
Which nerve innervates the esophagus and is part of the vagus nerve system?
What is the primary responsibility of the right recurrent laryngeal nerve?
What is the primary responsibility of the right recurrent laryngeal nerve?
Which nerve is associated with both voluntary and involuntary control of the organs within the thoracic cavity?
Which nerve is associated with both voluntary and involuntary control of the organs within the thoracic cavity?
In which anatomical region does the right recurrent laryngeal nerve take its path?
In which anatomical region does the right recurrent laryngeal nerve take its path?
What is a common clinical manifestation of damage to the recurrent laryngeal nerves?
What is a common clinical manifestation of damage to the recurrent laryngeal nerves?
Which structure receives deoxygenated blood from the body?
Which structure receives deoxygenated blood from the body?
What is the primary function of the left ventricle in the heart?
What is the primary function of the left ventricle in the heart?
Which structure separates the left atrium from the left ventricle?
Which structure separates the left atrium from the left ventricle?
In which anatomical space would you find the apex of the heart?
In which anatomical space would you find the apex of the heart?
Which chamber of the heart has the thickest muscular wall?
Which chamber of the heart has the thickest muscular wall?
Which of the following antibodies is known for its pentameric structure?
Which of the following antibodies is known for its pentameric structure?
Which artery does NOT arise from the internal thoracic artery?
Which artery does NOT arise from the internal thoracic artery?
What is the significance of the 2nd left intercostal space in a clinical examination?
What is the significance of the 2nd left intercostal space in a clinical examination?
Which of these statements about intercostal spaces is true?
Which of these statements about intercostal spaces is true?
What structure is typically located in the 6th right intercostal space?
What structure is typically located in the 6th right intercostal space?
What process does opsonization specifically refer to?
What process does opsonization specifically refer to?
Which cell type is NOT directly involved in the opsonization process?
Which cell type is NOT directly involved in the opsonization process?
How are pathogens targeted for destruction during opsonization?
How are pathogens targeted for destruction during opsonization?
What is the primary cellular response involved in inflammation that allows for the movement of immune cells?
What is the primary cellular response involved in inflammation that allows for the movement of immune cells?
In which form is the least amount of iron found in the human body?
In which form is the least amount of iron found in the human body?
Flashcards
Blood viscosity increase
Blood viscosity increase
Increased hematocrit directly increases blood's thickness (viscosity).
Blood components
Blood components
Albumin, glucose, urea, and water are crucial components of blood.
Capillary junctions
Capillary junctions
Tight junctions mainly make up the junctions between endothelial cells in capillaries.
Location of tight junctions
Location of tight junctions
Tight junctions primarily occur in capillaries.
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Hematocrit and viscosity
Hematocrit and viscosity
Higher hematocrit leads to increased blood viscosity.
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Reticulocyte
Reticulocyte
A type of immature red blood cell.
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Opsonization
Opsonization
Process tagging pathogens for phagocytosis.
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CFU-B
CFU-B
Colony-forming unit for B cells (Bone marrow).
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CFU-S
CFU-S
Colony-forming unit for stem cells.
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Proerythroblast
Proerythroblast
An early erythroid precursor cell.
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Smooth endothelial surface
Smooth endothelial surface
The inner lining of blood vessels, composed of endothelial cells, has a smooth surface to minimize friction and allow blood to flow easily.
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Plasmin
Plasmin
An enzyme that dissolves fibrin clots, helping to break down blood clots and restore normal blood flow.
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Heparin
Heparin
A natural anticoagulant that prevents blood clotting by inhibiting the formation of thrombin, a key enzyme in the clotting process.
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Fibrin fibers
Fibrin fibers
Thread-like proteins that form a mesh-like network during blood clotting, trapping blood cells and forming a stable clot.
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Last line of defense against infection
Last line of defense against infection
This refers to the immune system, which acts as the final barrier against invading pathogens, mounting a specific and targeted response to eliminate infections.
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Esophagus
Esophagus
The muscular tube connecting the throat (pharynx) to the stomach, responsible for transporting food.
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Right Vagus Nerve
Right Vagus Nerve
One of the two vagus nerves, it controls various body functions including heart rate, digestion, and respiratory rate. It's located on the right side of the body.
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Right Recurrent Laryngeal Nerve
Right Recurrent Laryngeal Nerve
A branch of the right vagus nerve that loops under the right subclavian artery before ascending to the larynx, responsible for voice production.
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Left Vagus Nerve
Left Vagus Nerve
One of the two vagus nerves, it controls various body functions including heart rate, digestion, and respiratory rate. It's located on the left side of the body.
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Vertebral canal
Vertebral canal
The hollow space within the vertebral column, which encloses and protects the spinal cord.
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Right atrium
Right atrium
The upper chamber of the heart on the right side, receiving deoxygenated blood from the body.
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Right ventricle
Right ventricle
The lower chamber of the heart on the right side, pumping deoxygenated blood to the lungs.
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Left atrium
Left atrium
The upper chamber of the heart on the left side, receiving oxygenated blood from the lungs.
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Left ventricle
Left ventricle
The lower chamber of the heart on the left side, pumping oxygenated blood to the body.
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Pentamere structure
Pentamere structure
A protein structure with five identical subunits arranged together.
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Internal thoracic artery branches
Internal thoracic artery branches
The internal thoracic artery supplies blood to the chest wall and gives rise to several important branches, including the anterior intercostal arteries, the musculophrenic artery, and the superior epigastric artery.
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Anterior intercostal arteries
Anterior intercostal arteries
These arteries arise from the internal thoracic artery and supply blood to the intercostal spaces, which are the spaces between the ribs.
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Musculophrenic artery
Musculophrenic artery
A branch of the internal thoracic artery that continues towards the diaphragm, supplying blood to the diaphragm and the muscles of the abdominal wall.
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Superior epigastric artery
Superior epigastric artery
Another branch of the internal thoracic artery that descends into the abdomen, supplying blood to the upper abdominal wall structures.
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Pericardium
Pericardium
A sac-like structure that encloses the heart, providing protection and lubrication.
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Circulatory Physiology
- Arteries transport blood under high pressure to tissues.
- Veins collect blood from capillaries, merging into larger veins.
- Capillary hydrostatic pressure forces fluid & dissolved substances into interstitial spaces.
- Approximate average net filtration pressure of capillaries is about 20 mmHg.
- Arterioles are the smallest arterial branches, controlling blood flow.
Blood Flow in Circulation
- Overall blood flow in adult rest is about 5000 ml/min.
- Albumin has less permeability compared to other molecules like glucose and water.
- Increasing hematocrit directly increases blood viscosity.
- Tight junctions are found between capillary endothelial cells in the kidney, spleen, liver, and brain.
Blood Reservoirs and Blood Flow Rate
- Edema in legs may be a symptom in people standing long periods with varicose veins.
- Rate of blood flow through the entire circulatory system equals cardiac output.
- Inhibition of sympathetic activity dilates blood vessels and increase blood flow.
- In aortic valve stenosis, aortic pressure pulse is significantly decreased.
Colloid Osmotic Pressure
- Albumin plays a significant role in colloid osmotic pressure.
- The aortic arc baroreceptors send signals to the vasomotor center through the vagus and glossopharyngeal nerves.
Hematocrit
- Hematocrit is elevated above normal range in polycythemia.
- The brain's vasomotor center controls vasoconstriction.
Blood Flow, Blood Pressure, and other factors
- Based on Ohm's law, higher pressure difference leads to increased blood flow.
Blood Cells and Components
- Proerythroblast is the first cell identified in the RBC series.
- Opsonization involves a process where pathogens are marked for phagocytosis.
- Iron in the human body is minimally present as ferritin.
- Leukemic cells often show metastatic growth in abnormal body areas.
Blood Clotting
- Thrombin does not directly affect factor VI.
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