Chronic Kidney Disease Overview
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Questions and Answers

Which symptom is NOT commonly associated with anemia?

  • Pale skin
  • Difficulty breathing
  • Elevated blood glucose (correct)
  • Headaches
  • What is the primary action of ACE inhibitors in managing blood pressure?

  • Block the action of angiotensin II (correct)
  • Prevent calcium from entering cells
  • Enhance kidney filtration
  • Increase aldosterone release
  • What potential complication can arise from untreated infections in kidney disease patients?

  • Increased physical activity
  • Improved wound healing
  • Tissue necrosis (correct)
  • Decreased blood pressure
  • Calcium channel blockers primarily help manage blood pressure through which mechanism?

    <p>By relaxing muscle cells in arterial walls (D)</p> Signup and view all the answers

    Which medication is typically used to decrease phosphate absorption in dialysis patients?

    <p>Phosphate binders (C)</p> Signup and view all the answers

    Angiotensin receptor blockers (ARBs) primarily function by blocking which substance?

    <p>Angiotensin II (C)</p> Signup and view all the answers

    Which of the following is a consequence of insufficient blood supply to tissues in kidney disease?

    <p>Tissue death (A)</p> Signup and view all the answers

    What is a common characteristic shared by ACE inhibitors?

    <p>They block angiotensin I conversion. (D)</p> Signup and view all the answers

    Which symptom is commonly associated with hypernatremia?

    <p>Twitching (B)</p> Signup and view all the answers

    What is a potential complication of hypokalemia?

    <p>Cardiac arrhythmias (A)</p> Signup and view all the answers

    Which dietary modification is most critical for patients managing kidney disease?

    <p>Low sodium intake (D)</p> Signup and view all the answers

    Which of the following is a common symptom of hypocalcemia?

    <p>Tetany (C)</p> Signup and view all the answers

    What medication effect should be monitored for patients at risk of hyperkalemia?

    <p>Muscle weakness (A)</p> Signup and view all the answers

    What does dry weight refer to in the context of hemodialysis?

    <p>The lowest weight a patient can tolerate after hemodialysis. (B)</p> Signup and view all the answers

    Which of the following is a sign of fluid volume excess before hemodialysis?

    <p>Bounding pulse (C)</p> Signup and view all the answers

    What serious complications can arise from long-term intradialytic hypotension?

    <p>Myocardial infarction and stroke (A)</p> Signup and view all the answers

    Which of the following does NOT directly affect blood pressure?

    <p>Heart rate variability (C)</p> Signup and view all the answers

    What is the relationship between fluid removal during hemodialysis and hypotension?

    <p>Fluid removal can lead to hypotension if not replaced quickly. (C)</p> Signup and view all the answers

    What is a common dietary restriction for patients undergoing hemodialysis?

    <p>Sodium restriction (D)</p> Signup and view all the answers

    How is euvolemia maintained in patients undergoing hemodialysis?

    <p>By achieving and maintaining a stable dry weight. (C)</p> Signup and view all the answers

    What is NOT a typical sign of hypovolemia during hemodialysis?

    <p>Bounding pulse (C)</p> Signup and view all the answers

    What does peripheral/pitting edema indicate in kidney patients before dialysis?

    <p>Hypervolemia (B)</p> Signup and view all the answers

    Which statement best explains osmosis in relation to hemodialysis?

    <p>Osmosis allows fluid from tissues to move into blood after fluid removal. (A)</p> Signup and view all the answers

    What is the recommended timing for taking calcium carbonate pills?

    <p>With meals, unless advised otherwise (C)</p> Signup and view all the answers

    Which of the following foods is high in potassium and should be limited for patients with kidney disease?

    <p>Bananas (C)</p> Signup and view all the answers

    What is a crucial dietary consideration for patients with kidney disease regarding protein intake?

    <p>Too much protein can lead to urea buildup (A)</p> Signup and view all the answers

    Which of the following symptoms may indicate fluid volume excess in a patient with kidney disease?

    <p>Increased respiratory rate (A)</p> Signup and view all the answers

    For patients on dialysis, what is the safe daily fluid intake generally considered?

    <p>500-1000 ml (A)</p> Signup and view all the answers

    Which medication should be taken between meals for optimal absorption?

    <p>Iron pills like ferrous gluconate (A)</p> Signup and view all the answers

    What complication may arise from excessive protein intake in kidney disease patients?

    <p>Urea buildup (C)</p> Signup and view all the answers

    Which type of food is particularly high in sodium and should be limited in a kidney diet?

    <p>Canned foods (A)</p> Signup and view all the answers

    Which symptom is NOT typically associated with fluid volume excess in kidney patients?

    <p>Increased energy levels (A)</p> Signup and view all the answers

    What should be included in the individualized meal plans for patients with kidney disease?

    <p>Restricted nutrient intake (B)</p> Signup and view all the answers

    What is a primary assessment for monitoring potential fluid volume excess before hemodialysis?

    <p>Daily weight measurement (C)</p> Signup and view all the answers

    Which of the following laboratory values should be checked to assess renal function?

    <p>BUN and creatinine (D)</p> Signup and view all the answers

    Which symptom indicates a possible electrolyte imbalance in a kidney patient during monitoring?

    <p>Elevated heart rate (A)</p> Signup and view all the answers

    What dietary restriction is commonly indicated for managing kidney disease?

    <p>Reduced protein consumption (B)</p> Signup and view all the answers

    Which sign is commonly assessed to monitor for signs of infection in kidney disease patients?

    <p>Leukocytosis (B)</p> Signup and view all the answers

    Which of the following is NOT a typical assessment performed on the abdominal system for kidney disease?

    <p>Monitor phosphorus levels (C)</p> Signup and view all the answers

    What monitoring action is important to take regarding heart function in kidney disease patients?

    <p>Evaluate for irregular heartbeats (A)</p> Signup and view all the answers

    Which health indicator is most critical to observe pre and post-dialysis?

    <p>Fluid volume status (B)</p> Signup and view all the answers

    Which vital sign assessment is essential while monitoring a patient’s respiratory system with kidney disease?

    <p>Monitor arterial blood gases (D)</p> Signup and view all the answers

    What is a potential complication of kidney disease that should be monitored?

    <p>Fluid retention (B)</p> Signup and view all the answers

    Flashcards

    Anemia Manifestations

    Symptoms of anemia include weakness, fatigue, headaches, concentration problems, pale skin, dizziness, difficulty breathing, chest pain, fast heartbeat (tachycardia), and irregular heartbeat.

    Kidney Disease Infections

    Patients with kidney disease are at higher risk for infections due to diabetes, impaired wound healing, and chronic wounds.

    ACE Inhibitors (Blood Pressure)

    Lower blood pressure by blocking angiotensin II formation, widening blood vessels, and reducing aldosterone release.

    ARBs (Blood Pressure)

    Lower blood pressure by blocking angiotensin II from binding to receptors, causing blood vessels to relax and widen.

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    Calcium Channel Blockers (Blood Pressure)

    Lower blood pressure by preventing calcium entry into heart and blood vessel cells, relaxing and widening blood vessels, and potentially slowing heart rate.

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    Phosphate Binders

    Used to reduce phosphate absorption from food, often used for dialysis patients, with calcium-based binders being a common choice.

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    Angiotensin II

    A hormone that narrows blood vessels, increasing blood pressure.

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    Tissue Necrosis

    Death of tissue due to insufficient blood flow.

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    Dry Weight in Hemodialysis

    The lowest weight a patient can tolerate after hemodialysis without symptoms of low or high blood volume (hypovolemia or hypervolemia).

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    Euvolemia

    A normal amount of fluid in the body.

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    Fluid Removal in Hemodialysis

    A large amount of fluid (usually over 2 liters) is removed from the patient's blood during hemodialysis.

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    Intradialytic Hypotension

    Low blood pressure during hemodialysis caused by slow fluid replacement after removal.

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    Hypovolemia

    Low blood volume, a fluid deficit.

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    Hypervolemia

    High blood volume, fluid excess.

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    Fluid Volume Excess Symptoms

    High blood pressure, rapid pulse, swollen veins, fast breathing, lung crackles, swelling, increased weight, headache, fatigue.

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    Fluid Volume Deficit

    Symptoms of low blood volume; opposite of fluid volume excess.

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    Hypoperfusion

    Low blood flow.

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    Osmosis in Hemodialysis

    Fluid shift from tissues/cells into blood vessels after fluid removal in hemodialysis.

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    Hyponatremia

    Low sodium in the blood. Symptoms include irritability, confusion, seizures, headache, nausea, vomiting, weight loss, dehydration, and lethargy.

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    Hypernatremia

    High sodium in the blood. Symptoms include intense thirst, restlessness, agitation, twitching, seizures, and coma.

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    Calcium Carbonate Pills

    Calcium carbonate pills should be taken with meals unless a nephrologist orders otherwise.

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    Iron Pills

    Iron pills, such as ferrous gluconate, should be taken between meals.

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    What foods are high in potassium?

    Foods high in potassium include potatoes, squash, bananas, oranges, tomatoes, and dried peas and beans.

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    What foods are high in sodium?

    Processed foods, like deli meats, canned foods, convenience foods, fast foods, salty snacks, and salty seasonings are high in sodium.

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    What foods are high in phosphorus?

    Milk, cheese, and other dairy products, as well as protein foods like meat, fish, and poultry, are high in phosphorus.

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    Why is protein important for kidney disease patients?

    Patients with kidney disease need to consume the right amount of protein. Too much protein can lead to a buildup of urea, while too little protein can lead to malnutrition and problems with tissue repair.

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    What is the usual fluid intake for dialysis patients?

    Fluid intake for dialysis patients is usually calculated by adding 400–600 ml to the patient's urine output. The extra 400–600 ml accounts for the fluid that is lost through the skin and lungs.

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    What is the usual fluid intake for dialysis patients who do not produce urine?

    For patients who do not produce urine, a safe daily fluid intake is between 500 and 1000 ml, which should limit weight gain to 0.5–1.0 kg.

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    What are some signs of fluid overload?

    Signs of fluid overload can include: increased blood pressure, bounding pulse, jugular vein distention, increased respiratory rate, shortness of breath, crackles in the lungs, peripheral/pitting edema, generalized edema, increased weight, headache, fatigue, and changes in activity.

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    Fluid Volume Excess

    A condition where the body retains too much fluid, leading to swelling and potential complications.

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    Acid-Base Imbalance

    A condition where the body's pH balance is disrupted, leading to potential complications.

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    Electrolyte Imbalance

    A condition where the body's electrolytes are out of balance, leading to potential complications.

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    Jugular Vein Distention

    A condition where the jugular vein in the neck is visibly distended, suggesting increased pressure in the heart and surrounding veins.

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    Peripheral Vascular Changes

    Changes in the blood vessels located in the limbs, including swelling, discoloration, temperature changes, and reduced pulse.

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    Costovertebral Tenderness

    Pain in the area where the ribs and spine meet, suggesting a possible problem with the kidneys.

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    Red Blood Cell Casts

    Red blood cells clumped together in the urine, indicating potential kidney damage.

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    Edema

    Swelling caused by fluid build-up in the tissues.

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    Bruits

    Abnormal swooshing sounds heard through a stethoscope, indicating turbulent blood flow in an artery.

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    Study Notes

    Chronic Kidney Disease (CKD)

    • CKD is defined as abnormalities of kidney structure or function that last for more than three months, impacting health.
    • Includes people with kidney damage and a glomerular filtration rate (GFR) below 60 mL/min/1.73 m2 on at least two occasions, 90 days apart, with or without kidney damage markers.
    • Characterized by progressive, irreversible loss of kidney function.
    • Nephons lose functionality, decreasing GFR; this leads to azotemia (waste buildup in the blood).

    Effects and Manifestations of CKD

    • Cardiovascular: Elevated blood pressure, heart rate, fluid retention (edema), dysrhythmias, abnormal heart sounds, pericardial friction rub.
    • Respiratory: Increased respiratory rate, Kussmaul respirations (deep, rapid breathing), crackles, decreased oxygen saturation, shortness of breath.
    • Renal: Reduced urine output, azotemia, proteinuria, hematuria, hyperuricemia.
    • Integumentary: Bruising, itching, dry skin, changes in skin color (ashen to yellowish), dry/brittle hair/nails.
    • Gastrointestinal: Anorexia, nausea, vomiting, halitosis, metallic taste, gastrointestinal bleeding.
    • Neurological: Peripheral neuropathy, restless legs syndrome, altered consciousness, lethargy, confusion, encephalopathy, motor function changes.
    • Musculoskeletal: Renal osteodystrophy (bone disease), decreased calcium levels, impaired Vitamin D metabolism, hyperparathyroidism, pathological fractures.
    • Immune: Increased susceptibility to infections (local and systemic).
    • Hematological: Anemia (weakness, fatigue, pallor, lethargy, bleeding).

    End-Stage Renal Disease (ESRD)

    • ESRD occurs when GFR falls below 15 mL/min/1.73 m2.
    • Kidneys lose filtering, secreting, reabsorbing, and excreting functions.
    • Requires renal replacement therapy for survival.

    Common Lab Tests and Findings in CKD

    • Creatinine: Breakdown product of creatinine phosphate in muscle; used to estimate kidney function, higher levels indicate lower filtration.
    • Blood Urea Nitrogen (BUN): Formed by liver during protein breakdown; filtered by kidneys; elevated BUN reflects reduced filtration.
    • Oliguria: Urine output less than 400-500 ml in 24 hours.
    • Anuria: Urine output less than 100 ml in 24 hours.

    Renal Replacement Therapies

    • Used when kidneys are unable to function properly (GFR<15 ml/min).
    • Peritoneal Dialysis: Uses the peritoneum (abdominal lining) as a membrane to filter fluids and waste; dialysate is placed in peritoneum (dwell), then drained.
    • Hemodialysis: Machine cleans blood, returning filtered blood to the patient; vascular access (fistula or catheter) is required.

    Key Concepts Not Covered by the Sources (General Information)

    • Five stages of CKD based on GFR levels.
    • Specific treatment options for each stage of CKD.
    • Complications associated with CKD (cardiovascular, bone disease, anemia, electrolyte imbalances)
    • Long-term CKD management (lifestyle, medications)

    Care of Patient Receiving Hemodialysis

    • Frequency: Typically three times a week for two hours each time.
    • Dry weight: Ideal weight patient can tolerate after dialysis without fluid volume issues.

    Acid-Base and Electrolytes

    • Pre-dialysis: Metabolic acidosis, high potassium, low sodium, low calcium, high phosphate, high magnesium, high glucose, uremia
    • Post-dialysis: Metabolic alkalosis (sometimes), electrolyte shifts (generally opposite of pre-dialysis imbalances)
    • Nursing Assessments: Monitor electrolyte imbalances like hyponatremia, hypernatremia, hypokalemia, hyperkalemia, hypocalcemia, hypercalcemia, hypophosphatemia, hyperphosphatemia including symptoms and potential issues

    Other Assessments (for patients)

    • Cardiovascular: Monitor blood pressure, pulses, edema, heart sounds, for fluid volume issues.
    • Respiratory: Assess breathing patterns, lung sounds, oxygen saturation.
    • Renal: Observe urine output, kidney palpation.
    • Integumentary: Skin conditions (dryness, bruising), color changes.
    • Gastrointestinal/Abdomen: Bowel sounds, abdomen size and firmness, signs of nausea, vomiting, or bleeding.
    • Neurological: Mental status, reflexes, alertness, potential confusion.

    Vascular Access Assessment

    • Inspection: Visual assessment for sores, infections, inflammation around the access site.
    • Palpation: Palpate for thrill, pulses above and below, capillary refill above and below the access site.
    • Auscultation: Presence of bruit over the access site.

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    Description

    Explore the fundamentals of Chronic Kidney Disease (CKD), which is defined by long-term abnormalities in kidney function. This quiz covers the effects and manifestations of CKD, including cardiovascular, respiratory, renal, and integumentary symptoms. Test your knowledge on this important health topic.

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