Chronic Kidney Disease Overview
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Questions and Answers

What is Chronic Kidney Disease (CKD)?

  • Temporary kidney dysfunction
  • Abnormalities in kidney structure or function lasting 3 months or longer (correct)
  • Sudden kidney failure
  • A type of cancer
  • How is CKD classified?

  • By age and gender
  • By symptoms only
  • By family history
  • By Glomerular Filtration Rate (GFR) and Albumin-to-Creatinine Ratio (uACR) (correct)
  • What factors influence the prognosis of CKD?

  • Cause of kidney disease, GFR at diagnosis, and albuminuria level (correct)
  • Age only
  • Family history alone
  • Gender
  • Which of the following is a clinical risk factor for CKD?

    <p>Diabetes</p> Signup and view all the answers

    Which sociodemographic factor is NOT a risk for CKD?

    <p>Blood type</p> Signup and view all the answers

    What is a key component of ESRD pathophysiology?

    <p>Nephron loss</p> Signup and view all the answers

    What lifestyle modification is recommended for CKD patients?

    <p>Smoking cessation</p> Signup and view all the answers

    First-line therapy for proteinuria management in diabetic CKD often includes:

    <p>ACE inhibitors or ARBs</p> Signup and view all the answers

    Study Notes

    Chronic Kidney Disease (CKD)

    • CKD is characterized by abnormalities in kidney structure or function lasting 3 months or longer
    • CKD is classified according to glomerular filtration rate (GFR) and albumin-to-creatinine ratio (uACR)
    • End-stage renal disease (ESRD) is defined as GFR < 15 mL/min/1.73 m² or requiring dialysis/kidney transplantation

    CKD Prognosis Factors

    • Factors influencing CKD prognosis: cause of kidney disease, GFR at diagnosis, and albuminuria level

    CKD Risk Factors

    • Key clinical risk factors identified include diabetes and high blood pressure

    CKD Pathophysiology and Symptoms

    • Key component of ESRD pathophysiology is nephron loss
    • Common symptoms in stages 4-5 of CKD include fatigue, weakness, and breathlessness

    CKD Treatment Goals

    • A major goal of CKD treatment is to delay or prevent disease progression

    CKD Medications/Lifestyle Modifications

    • First-line therapy for diabetic CKD often includes ACE inhibitors or ARBs
    • Sodium-glucose co-transporter 2 (SGLT-2) inhibitors are used to slow progression and reduce GFR decline.
    • Target blood pressure for CKD patients is <140/90 mm Hg
    • Common interventions for anemia of CKD include iron therapy
    • Target hemoglobin level for CKD patients on dialysis is 11-12 g/dL
    • Calcimimetics are used to manage secondary hyperparathyroidism in CKD
    • Phosphate-binding agents are used to manage hyperphosphatemia

    Other Key Information

    • CKD-related cardiovascular disease (CVD) is a major contributor to morbidity and mortality in CKD patients
    • Statins are used to manage CVD risk in CKD
    • KDIGO guidelines recommend against initiating statin therapy in dialysis-dependent CKD patients

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    Description

    This quiz delves into Chronic Kidney Disease (CKD), covering its classification, prognosis factors, risk factors, pathophysiology, symptoms, and treatment goals. Understand the key aspects and medications that play a role in managing CKD effectively.

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