Chronic Interstitial Lung Diseases Overview
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Questions and Answers

Which component of the pulmonary interstitium is fused in the thinnest portions?

  • Elastic tissue
  • Fibroblasts
  • Collagen fibers
  • Basement membrane of endothelial and epithelial cells (correct)

    • What is the hallmark feature of chronic interstitial lung diseases?

  • Elevated oxygen saturation
  • Decreased effort of breathing
  • Increased lung capacity
  • Reduced compliance (correct)

    • Which radiographic alteration is commonly seen in chest radiographs of patients with chronic interstitial lung diseases?

  • "Ground glass shadows" (correct)
  • Smooth lines
  • Large nodules
  • Regular borders

    • What is the characteristic histology pattern required for the diagnosis of Idiopathic Pulmonary Fibrosis (IPF)?

    <p>&quot;Usual interstitial pneumonia&quot;</p> Signup and view all the answers

    What type of T cell response is induced in the lesions of Idiopathic Pulmonary Fibrosis (IPF)?

    <p>TH2</p> Signup and view all the answers

    What is released from injured type I pneumocytes and induces transformation of fibroblasts into myofibroblasts in Idiopathic Pulmonary Fibrosis (IPF)?

    <p>TGF-beta1</p> Signup and view all the answers

    'Exuberant fibroblastic or myofibroblastic proliferation' is a characteristic feature in IPF at the sites of what?

    <p>Inflammation</p> Signup and view all the answers

    Which component downregulates fibroblast caveolin-1 in the pathogenesis of Idiopathic Pulmonary Fibrosis (IPF)?

    <p>TGF-beta1</p> Signup and view all the answers

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