Chronic Inflammation: Causes, Processes, and Outcomes Quiz
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Questions and Answers

Which cell type is the dominant cell type activated in chronic inflammation?

  • Macrophages (correct)
  • Eosinophils
  • Lymphocytes
  • Mast cells
  • What is a characteristic feature of granuloma formation?

  • Absence of lymphocytes
  • Contains the injurious agent and attempts to eradicate it (correct)
  • Presence of neutrophils
  • Proliferation of fibroblasts
  • What type of granuloma is typically seen with tuberculosis (TB)?

  • Non-caseating granuloma
  • Caseating granuloma (correct)
  • Necrotizing granuloma
  • Angiogenic granuloma
  • Which of the following is NOT a systemic sign associated with chronic inflammation?

    <p>Elevated white blood cell count</p> Signup and view all the answers

    What is the main function of plasma cells in chronic inflammation?

    <p>Producing antibodies</p> Signup and view all the answers

    Which of the following is a feature of chronic inflammation that distinguishes it from acute inflammation?

    <p>Fibrosis and tissue destruction</p> Signup and view all the answers

    Which of the following best describes chronic inflammation?

    <p>May occur without acute inflammation and involves simultaneous injury and healing</p> Signup and view all the answers

    What are the main causes of chronic inflammation according to the text?

    <p>Persistent infection by microorganisms, autoimmune diseases, prolonged exposure to toxic agents</p> Signup and view all the answers

    Which cells are involved in the infiltration during chronic inflammation?

    <p>Macrophages, lymphocytes, and plasma cells</p> Signup and view all the answers

    What is a key feature of the morphology of chronic inflammation?

    <p>Tissue destruction and attempts at healing by connective tissue replacement</p> Signup and view all the answers

    How does chronic inflammation differ from acute inflammation?

    <p>Prolonged duration and might not exhibit the classic signs of acute inflammation</p> Signup and view all the answers

    What are some systemic effects of chronic inflammation according to the text?

    <p>Impaired wound healing</p> Signup and view all the answers

    Chronic inflammation is always preceded by acute inflammation.

    <p>False</p> Signup and view all the answers

    The morphology of chronic inflammation involves infiltration of eosinophils and neutrophils.

    <p>False</p> Signup and view all the answers

    Chronic inflammation lasts for a short duration, typically days to weeks.

    <p>False</p> Signup and view all the answers

    Angiogenesis and fibrosis are key features of the morphology of acute inflammation.

    <p>False</p> Signup and view all the answers

    Chronic inflammation can only occur due to persistent infection by microorganisms.

    <p>False</p> Signup and view all the answers

    Chronic inflammation is always characterized by the 5 classic signs of acute inflammation.

    <p>False</p> Signup and view all the answers

    Eosinophils are the dominant cell type activated in chronic inflammation.

    <p>False</p> Signup and view all the answers

    Granuloma formation can only be caused by infectious organisms such as TB and leprosy.

    <p>False</p> Signup and view all the answers

    During chronic inflammation, the main function of lymphocytes is to directly kill injurious agents.

    <p>False</p> Signup and view all the answers

    Tissue necrosis is not associated with chronic inflammation.

    <p>False</p> Signup and view all the answers

    Angiogenesis is a common change observed in acute inflammation.

    <p>False</p> Signup and view all the answers

    Macrophage-lymphocyte interactions are not involved in granuloma formation in chronic inflammation.

    <p>False</p> Signup and view all the answers

    Chronic inflammation is always characterized by the 5 classic signs of acute inflammation.

    <p>False</p> Signup and view all the answers

    Granuloma formation can only be caused by infectious organisms such as TB and leprosy.

    <p>False</p> Signup and view all the answers

    Macrophage-lymphocyte interactions are not involved in granuloma formation in chronic inflammation.

    <p>False</p> Signup and view all the answers

    Angiogenesis is a common change observed in acute inflammation.

    <p>False</p> Signup and view all the answers

    During chronic inflammation, the main function of lymphocytes is to directly kill injurious agents.

    <p>False</p> Signup and view all the answers

    The morphology of chronic inflammation involves infiltration of eosinophils and neutrophils.

    <p>False</p> Signup and view all the answers

    Macrophages are not the dominant cell type activated in chronic inflammation.

    <p>False</p> Signup and view all the answers

    Granuloma formation is only associated with infectious organisms and not with autoimmune conditions.

    <p>False</p> Signup and view all the answers

    Eosinophils play a minor role in chronic inflammation compared to neutrophils.

    <p>True</p> Signup and view all the answers

    Tissue necrosis is not a common feature associated with chronic inflammation.

    <p>False</p> Signup and view all the answers

    Angiogenesis is not observed as a change in chronic inflammation.

    <p>False</p> Signup and view all the answers

    Plasma cells in chronic inflammation mainly act through direct killing of injurious agents.

    <p>False</p> Signup and view all the answers

    Study Notes

    • Chronic inflammation is a condition where inflammation persists for months or years, either following acute inflammation or without it.
    • Unlike acute inflammation, chronic inflammation is not characterized by the five signs of inflammation: redness, heat, swelling, pain, and loss of function.
    • Chronic inflammation is marked by the infiltration of mononuclear cells, including macrophages, lymphocytes, plasma cells, and other immune cells, into the affected tissue.
    • Macrophages are the dominant cell type in chronic inflammation, producing substances that can cause tissue damage and fibrosis.
    • Lymphocytes produce cytokines and contribute to the immune response in chronic inflammation.
    • In chronic inflammation, fibroblasts proliferate and cause fibrosis, leading to structural destruction and replacement of damaged tissue.
    • Granulomas, a special type of chronic inflammation, form in response to persistent inflammatory stimuli and can contain the injurious agent and attempt to eradicate it.
    • Granulomas can be caused by persistent infections, such as tuberculosis, leprosy, and syphilis, or exposure to exogenous materials like asbestos and silica.
    • Chronic inflammation is associated with systemic signs, including low-grade fever, weight loss, and anemia.

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    Description

    Test your knowledge on the concept and causes of chronic inflammation, processes involved, morphology, systemic effects, and main outcomes. Learn about chronic inflammation and its impact on health.

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