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Questions and Answers
What is a characteristic feature of foreign body granuloma?
What is a characteristic feature of foreign body granuloma?
- Formation of abscesses
- Presence of necrotic tissue
- Rapid resolution of inflammation
- Presence of giant cells and epithelioid cells (correct)
Which material is most likely to cause immune granuloma?
Which material is most likely to cause immune granuloma?
- Organic debris
- Insoluble, poorly degradable materials (correct)
- Soluble, easily degradable materials
- Surgical sutures
Which of the following statements best describes foreign body granuloma?
Which of the following statements best describes foreign body granuloma?
- It is often associated with infectious agents.
- It indicates a hypersensitivity reaction.
- It can be caused by materials such as sutures. (correct)
- It resolves quickly without treatment.
What type of cell is NOT typically found in immune granuloma?
What type of cell is NOT typically found in immune granuloma?
What is the primary factor that differentiates immune granuloma from foreign body granuloma?
What is the primary factor that differentiates immune granuloma from foreign body granuloma?
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Study Notes
Chronic Inflammation
- Chronic inflammation occurs over a prolonged period, in contrast to acute inflammation, which is rapid and short-lived.
- Chronic inflammation often accompanies persistent injury or infections.
- It is characterized by the presence of lymphocytes, macrophages, and plasma cells.
Granulomatous Inflammation
- Granulomatous inflammation is a distinctive form of chronic inflammation.
- It is characterized by the formation of granulomas, which are microscopic aggregates of inflammatory cells.
- Granulomas are typically organized around a central nidus, which can be a foreign body, persistent infectious agent, or other antigen.
Types of Granulomas
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Foreign body granulomas develop around large, inert materials that cannot be readily phagocytosed by macrophages.
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Examples include suture material, talc, or surgical sponge fragments.
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Giant cells and epithelioid cells surround the foreign body, attempting to encapsulate and isolate it.
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Immune granulomas develop in response to insoluble, poorly degradable materials that induce an immune response.
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These materials can be biological agents like Mycobacterium tuberculosis, fungi, or parasites.
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The immune response involves T lymphocytes and macrophages, leading to the formation of granulomas.
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