Chromosome Segregation Errors Quiz
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Questions and Answers

What is a major consequence of segregation defects during cell division?

  • Improved gene expression in the progeny cells
  • Change in the relative dosage of products from genes located on the missegregated chromosomes (correct)
  • Increased number of chromosomes in the progeny cells
  • Enhanced stability of the organism

What can abnormal expression of transcriptional regulators impact?

  • Genes on the properly segregated chromosomes (correct)
  • Cell division frequency
  • Chromosome content in the progeny cells
  • Mitotic spindle formation

What are the consequences of perturbations in gene expression dependent on?

  • The specific chromosomes affected and the interplay of the aneuploid phenotype with the environment (correct)
  • The number of cell divisions
  • The type of cell membrane
  • The size of the cells

What is the impact of novel chromosome distributions on the health and survival of the organism?

<p>Most often detrimental (D)</p> Signup and view all the answers

What do mistakes during cell division frequently generate?

<p>Changes in chromosome content (B)</p> Signup and view all the answers

What is the impact of mitotic errors on tumor responsiveness to immunotherapy?

<p>They can impact tumor responsiveness to immunotherapy (C)</p> Signup and view all the answers

What is the primary role of mitosis in ensuring genomic stability?

<p>To ensure genomic stability (B)</p> Signup and view all the answers

How do mitotic errors shape cancer genomes?

<p>By driving numerical and structural alterations in chromosomes (D)</p> Signup and view all the answers

What vulnerabilities are exposed by cell division errors?

<p>Vulnerabilities that can be exploited therapeutically (A)</p> Signup and view all the answers

What do new findings suggest about chromosome missegregation?

<p>It can produce a proinflammatory environment (A)</p> Signup and view all the answers

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