Podcast
Questions and Answers
What determines the 'individuality' of a cell within the nucleus?
What determines the 'individuality' of a cell within the nucleus?
- The preferred positions of chromosomal territories (correct)
- The level of transcriptional activity in chromosome compartments
- The size of the nucleus
- The intermingling of gene-rich and gene-poor regions
Where is gene-rich chromatin typically located within the nucleus?
Where is gene-rich chromatin typically located within the nucleus?
- Topologically associated domains
- Periphery
- Intermingled with gene-poor regions
- Central (correct)
What are the characteristics of Chromosome Compartment A?
What are the characteristics of Chromosome Compartment A?
- Conserved between different cell types
- Interacts weakly with other regions
- Gene poor and transcriptionally silent
- Gene rich and transcriptionally active (correct)
What are Topologically Associated Domains (TADs) characterized by?
What are Topologically Associated Domains (TADs) characterized by?
What drives the interaction between Chromosome Compartments A and B?
What drives the interaction between Chromosome Compartments A and B?
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