Cholinergic Transmission Sites Quiz
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Questions and Answers

What ion influx causes ACh release into the synaptic cleft?

  • Sodium
  • Chloride
  • Calcium (correct)
  • Potassium
  • Which type of receptors are found in the skeletal muscle motor?

  • M2
  • Muscarinic
  • Nn
  • Nm (correct)
  • Which type of receptors are blocked by d-(tubocurarine)?

  • Nm (correct)
  • M3
  • M1
  • M2
  • Where are Nn (nicotinic neuronal) receptors predominantly found?

    <p>Adrenal medulla</p> Signup and view all the answers

    Which part of the body contains muscarinic receptors M3?

    <p>Bladder wall</p> Signup and view all the answers

    Where are Muscarinic receptors M1 primarily located?

    <p>Stomach</p> Signup and view all the answers

    How is Acetylcholine synthesized in the nerve terminal?

    <p>By combining choline and acetyl COA using choline acetyl transferase enzyme</p> Signup and view all the answers

    Which enzyme is responsible for hydrolysis of Acetylcholine?

    <p>Acetyl cholinesterase</p> Signup and view all the answers

    What inhibits the uptake of choline into the nerve terminal?

    <p>Hemicholinium</p> Signup and view all the answers

    Which enzyme is found mainly in plasma and liver and hydrolyzes Acetylcholine?

    <p>Butyryl cholinesterase</p> Signup and view all the answers

    What prevents the release of Acetylcholine and is used in blepharospasm, dystonia, and cosmetics?

    <p>Botulinum toxin</p> Signup and view all the answers

    What increases the release of Ach in the gastrointestinal tract?

    <p>Metoclopramide</p> Signup and view all the answers

    Which type of receptors does acetylcholine act on?

    <p>Muscarinic and nicotinic receptors</p> Signup and view all the answers

    Which type of nerve endings stimulate the release of acetylcholine?

    <p>Botulinum toxin-inhibited nerve terminals</p> Signup and view all the answers

    In which type of ganglia is acetylcholine not a specific neurotransmitter?

    <p>Sympathetic postganglionic nerve endings</p> Signup and view all the answers

    Which neurotransmitter is released by preganglionic parasympathetic fibers and postganglionic sympathetic fibers for muscarinic cholinergic receptors?

    <p>Acetylcholine; Norepinephrine; Acetylcholine</p> Signup and view all the answers

    Which statement concerning the parasympathetic nervous system is correct?

    <p>The postganglionic fibers of the parasympathetic division are short compared to the sympathetic system</p> Signup and view all the answers

    What is the approximate half-life of acetylcholine in plasma?

    <p>8 to 10 hours</p> Signup and view all the answers

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