Cholinergic Transmission Sites Quiz
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Questions and Answers

What ion influx causes ACh release into the synaptic cleft?

  • Sodium
  • Chloride
  • Calcium (correct)
  • Potassium

Which type of receptors are found in the skeletal muscle motor?

  • M2
  • Muscarinic
  • Nn
  • Nm (correct)

Which type of receptors are blocked by d-(tubocurarine)?

  • Nm (correct)
  • M3
  • M1
  • M2

Where are Nn (nicotinic neuronal) receptors predominantly found?

<p>Adrenal medulla (C)</p> Signup and view all the answers

Which part of the body contains muscarinic receptors M3?

<p>Bladder wall (D)</p> Signup and view all the answers

Where are Muscarinic receptors M1 primarily located?

<p>Stomach (A)</p> Signup and view all the answers

How is Acetylcholine synthesized in the nerve terminal?

<p>By combining choline and acetyl COA using choline acetyl transferase enzyme (B)</p> Signup and view all the answers

Which enzyme is responsible for hydrolysis of Acetylcholine?

<p>Acetyl cholinesterase (C)</p> Signup and view all the answers

What inhibits the uptake of choline into the nerve terminal?

<p>Hemicholinium (A)</p> Signup and view all the answers

Which enzyme is found mainly in plasma and liver and hydrolyzes Acetylcholine?

<p>Butyryl cholinesterase (C)</p> Signup and view all the answers

What prevents the release of Acetylcholine and is used in blepharospasm, dystonia, and cosmetics?

<p>Botulinum toxin (A)</p> Signup and view all the answers

What increases the release of Ach in the gastrointestinal tract?

<p>Metoclopramide (B)</p> Signup and view all the answers

Which type of receptors does acetylcholine act on?

<p>Muscarinic and nicotinic receptors (A)</p> Signup and view all the answers

Which type of nerve endings stimulate the release of acetylcholine?

<p>Botulinum toxin-inhibited nerve terminals (A)</p> Signup and view all the answers

In which type of ganglia is acetylcholine not a specific neurotransmitter?

<p>Sympathetic postganglionic nerve endings (A)</p> Signup and view all the answers

Which neurotransmitter is released by preganglionic parasympathetic fibers and postganglionic sympathetic fibers for muscarinic cholinergic receptors?

<p>Acetylcholine; Norepinephrine; Acetylcholine (D)</p> Signup and view all the answers

Which statement concerning the parasympathetic nervous system is correct?

<p>The postganglionic fibers of the parasympathetic division are short compared to the sympathetic system (B)</p> Signup and view all the answers

What is the approximate half-life of acetylcholine in plasma?

<p>8 to 10 hours (C)</p> Signup and view all the answers

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