Cholinergic Drugs Classification and Effects Quiz
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Questions and Answers

Miosis is a dilation of the pupil.

False

Pilocarpine is an indirect-acting cholinergic drug.

False

Bethanechol is used to treat glaucoma.

False

Methacholine is commonly used in the diagnosis of bronchial airway hyperreactivity.

<p>True</p> Signup and view all the answers

Excessive pilocarpine usage can lead to pupil dilation.

<p>False</p> Signup and view all the answers

Cholinergic drugs that act on the receptor are categorized as indirect-acting cholinergic drugs.

<p>False</p> Signup and view all the answers

Organophosphates are classified as reversible indirect cholinergic drugs.

<p>False</p> Signup and view all the answers

Pilocarpine is an example of an indirect cholinergic drug.

<p>False</p> Signup and view all the answers

Acetylcholine (Ach) binds to Muscarinic M4 receptor in the heart.

<p>False</p> Signup and view all the answers

Muscarinic receptors are divided into M1, M2, M3, M4 and M5 subtypes.

<p>True</p> Signup and view all the answers

Cholinergic drugs mimic the action of norepinephrine (NE).

<p>False</p> Signup and view all the answers

Activation of Muscarinic M3 receptors leads to relaxation of ciliary muscles in the eye.

<p>False</p> Signup and view all the answers

What is the primary effect of activation of Muscarinic M3 receptors in the lungs?

<p>Bronchoconstriction</p> Signup and view all the answers

Which of the following is NOT a response to the activation of Muscarinic M3 receptors?

<p>Bronchodilation</p> Signup and view all the answers

Which cholinergic drug is commonly used to diagnose bronchial airway hyperreactivity?

<p>Methacholine</p> Signup and view all the answers

What is the effect of pilocarpine on intraocular pressure (IOP)?

<p>Lowers IOP</p> Signup and view all the answers

Which organ system does bethanechol primarily affect?

<p>Bladder</p> Signup and view all the answers

In the context of cholinergic drugs, what do indirect-acting cholinergic drugs act on?

<p>Function independently of AChE</p> Signup and view all the answers

Which cholinergic receptor subtype is responsible for reducing heart rate and contractile strength in the atria?

<p>M2</p> Signup and view all the answers

Which muscarinic receptor subtype is predominantly found in the CNS?

<p>M1</p> Signup and view all the answers

Acetylcholine binding to which muscarinic receptor subtype leads to suppression of cardiac activity?

<p>M2</p> Signup and view all the answers

Which cholinomimetic drug is topically administered and is associated with clinical uses related to pupil constriction and glaucoma?

<p>Pilocarpine</p> Signup and view all the answers

Which muscarinic receptor subtype is responsible for contraction of the ciliary muscles in the eye?

<p>M3</p> Signup and view all the answers

In which organ system would activation of Muscarinic M3 receptors lead to a response involving relaxation?

<p>Ciliary muscles in the eye</p> Signup and view all the answers

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