Chapter 21 pharm

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25 Questions

What is the main effect of cholinergic drugs?

Stimulate the parasympathetic nervous system

What is a potential adverse effect of anticholinergic drugs?

Decreased sweating

When should patients taking anticholinergic drugs contact their doctor?

If they have muscle cramps

What is the antidote to anticholinergic drugs?

Physostigmine

What effect do anticholinergic drugs have on heart rate?

They can increase heart rate with large doses

Which condition would be a contraindication for taking anticholinergic drugs?

Urinary retention

What is the potential consequence of giving anticholinergic drugs to patients with glaucoma?

Increased pupil dilation

What is the role of atropine among anticholinergic drugs?

It is used for bradycardia

What is the main effect of anticholinergic drugs?

Decrease in urine output

For which condition is the anticholinergic medication Dicyclomine/Bentyl commonly used?

IBS

What is the antidote for atropine, an anticholinergic drug?

Physostigmine

What is a potential adverse effect of anticholinergic drugs?

Hallucinations

What is the primary effect of anticholinergic drugs?

Blocking the action of acetylcholine

Which medication is commonly used for overactive bladder among anticholinergic drugs?

Oxybutynin/Ditropan

In what condition would anticholinergic drugs be given in the hospital before surgery?

To avoid aspiration

What is the primary role of Glycopyrrolate/Robinul, an anticholinergic drug?

Controlling production of secretions

Which condition can be treated using Scopolamine, an anticholinergic medication?

Motion sickness

How do anticholinergic drugs affect the parasympathetic nervous system?

They block it

What is the potential risk for patients taking anticholinergic drugs?

Higher risk for heat stroke

What is the effect of anticholinergic drugs on the internal sphincter?

Increased constriction causing urinary retention

Which of the following conditions can be treated using anticholinergic medications?

Irritable bowel syndrome (IBS)

What is a potential use of anticholinergic drugs?

For patients with COPD

What is a potential condition for which anticholinergic drugs might not be suitable?

Glaucoma

Anti-Cholinergic drugs dry you out.

True

Before an operation, what anticholinergic drug would you see given to a patient?

Glycopyrrolate/Robinul

Study Notes

Anticholinergic Drugs

  • Main effect: Inhibit the action of acetylcholine, a neurotransmitter that stimulates muscle contractions and secretions.
  • Adverse effect: Dry mouth, blurred vision, urinary retention, constipation, and tachycardia.
  • Contact doctor: When experiencing adverse effects, such as difficulty urinating or allergic reactions.
  • Antidote: Physostigmine, which reverses the effects of anticholinergic overdose.
  • Effect on heart rate: Increases heart rate.
  • Contraindication: Glaucoma, as anticholinergic drugs can increase intraocular pressure.
  • Effect on glaucoma patients: Worsening of glaucoma symptoms.
  • Role of Atropine: Blocks the action of acetylcholine, used to treat bradycardia, organophosphate poisoning, and as a pre-anesthetic medication.
  • Main effect: Inhibit the parasympathetic nervous system, reducing secretions and muscle contractions.

Indications and Contraindications

  • Dicyclomine/Bentyl: Used to treat irritable bowel syndrome (IBS).
  • Anticholinergic medication for overactive bladder: Oxybutynin, Tolterodine, or Solifenacin.
  • Scopolamine: Used to treat motion sickness, nausea, and vomiting.
  • Pre-surgical use: Glycopyrrolate/Robinul, used to reduce secretions and prevent bronchospasms.
  • Primary role of Glycopyrrolate/Robinul: Reduces secretions and prevents bronchospasms during surgery.

Effects on the Body

  • Affects the parasympathetic nervous system: Reduces secretions and muscle contractions.
  • Effect on the internal sphincter: Relaxes the internal sphincter, increasing the risk of urinary retention.
  • Potential risk: Increased risk of heat stroke, especially in elderly patients.
  • Dry mouth: Anticholinergic drugs can dry out the mucous membranes, causing dry mouth.

Conditions Treated

  • Overactive bladder
  • Irritable bowel syndrome (IBS)
  • Motion sickness
  • Nausea and vomiting
  • Bradycardia
  • Organophosphate poisoning

Test your knowledge of cholinergic and anticholinergic drugs with this quiz. Explore the effects of these drugs on the parasympathetic nervous system and their impact on bodily functions.

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