Cholinergic Agents & Alzheimer's Disease
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Questions and Answers

What are the potential therapeutic applications of M receptor agonists and M receptor antagonists?

M receptor agonists are being investigated for the treatment of Alzheimer's disease, while M receptor antagonists may have potential therapeutic applications for conditions related to ACh.

What are direct-acting cholinergic agonists? Provide examples.

Direct-acting cholinergic agonists are drugs that directly stimulate cholinergic receptors. Example examples include drugs like nicotine and pilocarpine.

What is the difference between nicotine and pilocarpine in terms of receptor affinity?

Nicotine has a weak affinity for muscarinic receptors, whereas pilocarpine exhibits preferential binding to muscarinic receptors.

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