Chloroquine & Hydroxychloroquine for Malaria Prevention

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18 Questions

What is the recommended timing for starting prophylaxis with chloroquine or hydroxychloroquine before traveling to malaria-endemic areas?

1-2 weeks before travel

How often should travelers take chloroquine or hydroxychloroquine during travel in malaria-endemic areas?

Once every week

What is a reported side effect of chloroquine and hydroxychloroquine?

Blurred vision

What have high doses of chloroquine been associated with?

Retinopathy

Which serious side effect is considered extremely unlikely when using chloroquine for weekly malaria prophylaxis?

Retinopathy

In what situation might people better tolerate taking chloroquine?

With fatty meals

What condition can chloroquine and related compounds reportedly exacerbate?

Psoriasis

What is the alternative compound that a traveler experiencing side effects might better tolerate?

Hydroxychloroquine sulfate

What are the reported side effects of chloroquine and hydroxychloroquine?

Blurred vision and dizziness

What is the recommended timing for starting doxycycline prophylaxis before travel to malaria-endemic areas?

1-2 days before travel

How often should doxycycline be taken during travel in malaria-endemic areas?

Once a day

What gastrointestinal side effects are associated with doxycycline use?

Nausea and vomiting

How can the risk of photosensitivity caused by doxycycline be minimized?

Avoiding prolonged, direct exposure to the sun and using sunscreen

Who should not take doxycycline for malaria prophylaxis?

All of the above

What should people on a long-term regimen of minocycline do if they need malaria prophylaxis?

Stop taking minocycline 1-2 days before travel and start doxycycline instead

What is the association between doxycycline use and vaginal yeast infections?

Increased frequency of vaginal yeast infections

How can the risk for esophagitis caused by doxycycline be reduced?

Advising travelers to swallow the medicine with sufficient fluids and to avoid taking doxycycline shortly before going to bed

What is the recommended action for travelers who are on a long-term regimen of minocycline and need malaria prophylaxis after completing the full course of doxycycline?

Minocycline can be restarted after the full course of doxycycline is completed

Test your knowledge about the use of chloroquine phosphate or hydroxychloroquine sulfate (Plaquenil) for preventing malaria. Learn about the timing and dosage for prophylaxis during travel to malaria-endemic areas.

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