Chlamydia and Mycoplasmas

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Questions and Answers

Which method is used for the diagnosis of mycoplasma infection?

Serology (correct)

Cold agglutinin detection

Direct microscopical detection

PCR

What is the characteristic appearance of mycoplasma colonies?

Irregular with fuzzy edges

Star-shaped

Circular with a raised center

Fried-egg appearance (correct)

Why is cultivation of mycoplasma difficult?

It requires prolonged incubation (correct)

It is easily contaminated

It requires specialized equipment

It is resistant to most culture media

What is the significance of a four-fold rise in IgG antibody titer?

It is diagnostic for mycoplasma infection Signup and view all the answers

What does a cold agglutinin titer of >/= 1:128 indicate?

Recent mycoplasma infection Signup and view all the answers

What do cold agglutinins detect in mycoplasma infection?

Recent infection Signup and view all the answers

What can exposure to cold temperature lead to in mycoplasma infection?

Ischemia and necrosis of hands and feet Signup and view all the answers

What is the main reason for using serological tests in mycoplasma diagnosis?

Direct microscopical detection is of limited value Signup and view all the answers

What is the significance of detecting IgM antibodies in mycoplasma infection?

It indicates recent infection Signup and view all the answers

What is the limitation of PCR in mycoplasma diagnosis?

It does not distinguish between colonization and infection Signup and view all the answers

What is the characteristic appearance of mycoplasma colonies?

Fried-egg appearance Signup and view all the answers

Why are cold agglutinins detected in mycoplasma infection?

To indicate recent infection Signup and view all the answers

Which species is responsible for causing trachoma, a leading cause of blindness in hot and dry climates?

Chlamydia trachomatis Signup and view all the answers

What is the unique biphasic life cycle of Chlamydia characterized by?

Small extracellular metabolically inert particles and larger intracellular metabolically active particles Signup and view all the answers

How do Chlamydia infections manifest?

Genital tract infections, lymphogranuloma venereum, and inclusion conjunctivitis Signup and view all the answers

How do Chlamydia grow and replicate?

Inside host cells Signup and view all the answers

How are Chlamydia similar to viruses?

They can be grown on tissue culture in a lab Signup and view all the answers

How can Chlamydia be transmitted?

Through inhalation of respiratory droplets or during passage through an infected birth canal Signup and view all the answers

What is involved in the laboratory diagnosis of Chlamydia?

Direct detection, antigen detection, nucleic acid detection, and serological tests Signup and view all the answers

What is the recommended approach for treating and preventing Chlamydia infections?

Use of erythromycin and tetracycline, and detecting and treating asymptomatic individuals Signup and view all the answers

Which bacteria are similar to Chlamydia and are also bacteria without a cell wall?

Mycoplasmas Signup and view all the answers

What is a unique requirement for growing Mycoplasmas in the lab?

Serum-enriched medium containing cholesterol Signup and view all the answers

What are Mycoplasmas resistant to?

Antibiotics that inhibit cell wall synthesis Signup and view all the answers

Which species of Chlamydia is not mentioned in the text?

Chlamydia felis Signup and view all the answers

Study Notes

Chlamydia: Key Points

Chlamydia trachomatis has several serotypes, and it can cause sexually transmitted diseases in both males and females.
Trachoma, caused by serotypes A, B, or C, is a leading cause of blindness in hot and dry climates.
Chlamydiae that infect humans are divided into three species: Chlamydia trachomatis, Chlamydia pneumoniae, and Chlamydophila psittaci.
Chlamydia have a unique biphasic life cycle with two morphological forms: small extracellular metabolically inert particles and larger intracellular metabolically active particles.
Chlamydia infections can manifest as genital tract infections, lymphogranuloma venereum, and inclusion conjunctivitis.
Chlamydia lack the ability to produce sufficient energy to grow independently and can only grow inside host cells.
Chlamydia can be grown on tissue culture in a lab and are similar to viruses but are considered bacteria.
Chlamydia can be transmitted through inhalation of respiratory droplets or during passage through an infected birth canal.
Laboratory diagnosis of Chlamydia includes direct detection, antigen detection, nucleic acid detection, and serological tests.
Treatment and prevention of Chlamydia infections involve the use of erythromycin and tetracycline, and detecting and treating asymptomatic individuals is important.
Mycoplasmas, which are similar to Chlamydia, are bacteria without a cell wall and are the smallest bacteria that can be grown on cell-free media.
Mycoplasmas require serum-enriched medium containing cholesterol and are resistant to antibiotics that inhibit cell wall synthesis.

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Description

Test your knowledge about Chlamydia and Mycoplasmas with this informative quiz. Explore key points such as the unique life cycle, clinical manifestations, laboratory diagnosis, treatment, and prevention of these bacterial infections.