Chirality in Organic Compounds Quiz
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Questions and Answers

What is the main purpose of using OsO4 in the hydroxylation reaction of alkenes?

  • To give a trans 1,2-diol
  • To catalyze the Pinacol-Pinacolone rearrangement
  • To convert alkenes to cis-diol (correct)
  • To dehydrate gem diols

Why is OsO4 used in catalytic amounts in the hydroxylation reaction of alkenes?

  • Because it is toxic, volatile, and expensive (correct)
  • To prevent over-oxidation of the glycol
  • To increase the reaction yield
  • To accelerate the reaction rate

What happens to most gem diols in aqueous solutions?

  • They remain stable
  • They form 1,2-diols
  • They undergo hydroxylation reactions
  • They dehydrate to form aldehydes or ketones (correct)

What is the Pinacol-Pinacolone rearrangement?

<p>A method for converting 1,2-diols to carbonyl compounds (A)</p> Signup and view all the answers

What does the Pinacol-Pinacolone rearrangement involve in terms of steps?

<p>Protonation, carbocation formation, 1,2-rearrangement, deprotonation (B)</p> Signup and view all the answers

Which compound is formed from the acid-catalyzed dehydration of glycols?

<p>Ketone (D)</p> Signup and view all the answers

What is the outcome of treating an epoxide with aqueous acid?

<p>Formation of a trans 1,2-diol (A)</p> Signup and view all the answers

Why should OsO4 be used in limited quantities in reactions?

<p>To prevent over-oxidation of glycols (D)</p> Signup and view all the answers

What is a major disadvantage of using KMnO4 for the oxidation of alkenes?

<p>Potential over-oxidation (A)</p> Signup and view all the answers

In the Pinacol-Pinacolone rearrangement mechanism, what role does carbocation formation play?

<p>Facilitating a 1,2-rearrangement (D)</p> Signup and view all the answers
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