Chemotherapy Toxicities Quiz
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Questions and Answers

What is the primary goal of chemotherapy?

  • To induce autoimmunity
  • To inhibit malignant cell proliferation (correct)
  • To prevent cell death
  • To exacerbate tumor multiplication

Which system is frequently affected by immune checkpoint inhibitors?

  • Endocrine system (correct)
  • Muscular system
  • Cardiovascular system
  • Nervous system

What is a common toxic effect of traditional chemotherapeutic regimens?

  • Enhanced immune response
  • Increased heart rate
  • Improved digestive system function
  • Decreased white blood cell count (correct)

Which of the following is not one of the areas frequently affected by immune checkpoint inhibitors?

<p>Skeletal system (D)</p> Signup and view all the answers

What is the primary mechanism of action of traditional chemotherapy agents?

<p>Inhibiting nucleic acid synthesis (D)</p> Signup and view all the answers

Why is combination chemotherapy often used?

<p>To reduce the risk of toxic side effects (B)</p> Signup and view all the answers

Which of the following is NOT an adverse effect of Nivolumab?

<p>Neuropathy (C)</p> Signup and view all the answers

What is the mechanism of action of Nivolumab?

<p>Blocks the interaction between PD-1 and its ligands (B)</p> Signup and view all the answers

Which cancer type is NOT listed in the clinical uses of Nivolumab?

<p>Breast cancer (A)</p> Signup and view all the answers

Which statement about chemotherapy-induced vomiting is true?

<p>Anticipatory vomiting is mediated by the stimulation of chemotherapy drugs (A)</p> Signup and view all the answers

Which of these is NOT a drug commonly used to prevent and treat chemotherapy-induced nausea and vomiting?

<p>ACE inhibitors (D)</p> Signup and view all the answers

Among the common adverse effects mentioned, which one is associated with Stevens-Johnson syndrome (SJS)?

<p>Rash (C)</p> Signup and view all the answers

Why are normal tissues like bone marrow, hair follicles, and intestinal epithelium susceptible to damage from cytotoxic drugs?

<p>They are rapidly proliferating tissues. (D)</p> Signup and view all the answers

What is the main reason for using combination chemotherapy in cancer treatment?

<p>To enhance efficacy and minimize overlapping dose-limiting toxicity. (C)</p> Signup and view all the answers

Which of the following is NOT a significant adverse effect associated with chemotherapy drugs?

<p>Improved immune response (A)</p> Signup and view all the answers

Why is it challenging to specifically target altered cancer cells with chemotherapy drugs?

<p>Cancer cells have similar characteristics to normal human cells. (B)</p> Signup and view all the answers

Which chemotherapy drug is known for its use in targeting B cells in certain cancers?

<p>Busulfan (B)</p> Signup and view all the answers

What is a common adverse effect associated with the chemotherapy drug Cisplatin?

<p>Peripheral neuropathy (D)</p> Signup and view all the answers

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