Chemotherapy Toxicities Quiz

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What is the primary goal of chemotherapy?

To induce autoimmunity

To inhibit malignant cell proliferation (correct)

To prevent cell death

To exacerbate tumor multiplication

Which system is frequently affected by immune checkpoint inhibitors?

Endocrine system (correct)

Muscular system

Cardiovascular system

Nervous system

What is a common toxic effect of traditional chemotherapeutic regimens?

Enhanced immune response

Increased heart rate

Improved digestive system function

Decreased white blood cell count (correct)

Which of the following is not one of the areas frequently affected by immune checkpoint inhibitors?

Skeletal system Signup and view all the answers

What is the primary mechanism of action of traditional chemotherapy agents?

Inhibiting nucleic acid synthesis Signup and view all the answers

Why is combination chemotherapy often used?

To reduce the risk of toxic side effects Signup and view all the answers

Which of the following is NOT an adverse effect of Nivolumab?

Neuropathy Signup and view all the answers

What is the mechanism of action of Nivolumab?

Blocks the interaction between PD-1 and its ligands Signup and view all the answers

Which cancer type is NOT listed in the clinical uses of Nivolumab?

Breast cancer Signup and view all the answers

Which statement about chemotherapy-induced vomiting is true?

Anticipatory vomiting is mediated by the stimulation of chemotherapy drugs Signup and view all the answers

Which of these is NOT a drug commonly used to prevent and treat chemotherapy-induced nausea and vomiting?

ACE inhibitors Signup and view all the answers

Among the common adverse effects mentioned, which one is associated with Stevens-Johnson syndrome (SJS)?

Rash Signup and view all the answers

Why are normal tissues like bone marrow, hair follicles, and intestinal epithelium susceptible to damage from cytotoxic drugs?

They are rapidly proliferating tissues. Signup and view all the answers

What is the main reason for using combination chemotherapy in cancer treatment?

To enhance efficacy and minimize overlapping dose-limiting toxicity. Signup and view all the answers

Which of the following is NOT a significant adverse effect associated with chemotherapy drugs?

Improved immune response Signup and view all the answers

Why is it challenging to specifically target altered cancer cells with chemotherapy drugs?

Cancer cells have similar characteristics to normal human cells. Signup and view all the answers

Which chemotherapy drug is known for its use in targeting B cells in certain cancers?

Busulfan Signup and view all the answers

What is a common adverse effect associated with the chemotherapy drug Cisplatin?

Peripheral neuropathy Signup and view all the answers