Chemotherapy Toxicities Quiz

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18 Questions

What is the primary goal of chemotherapy?

To inhibit malignant cell proliferation

Which system is frequently affected by immune checkpoint inhibitors?

Endocrine system

What is a common toxic effect of traditional chemotherapeutic regimens?

Decreased white blood cell count

Which of the following is not one of the areas frequently affected by immune checkpoint inhibitors?

Skeletal system

What is the primary mechanism of action of traditional chemotherapy agents?

Inhibiting nucleic acid synthesis

Why is combination chemotherapy often used?

To reduce the risk of toxic side effects

Which of the following is NOT an adverse effect of Nivolumab?

Neuropathy

What is the mechanism of action of Nivolumab?

Blocks the interaction between PD-1 and its ligands

Which cancer type is NOT listed in the clinical uses of Nivolumab?

Breast cancer

Which statement about chemotherapy-induced vomiting is true?

Anticipatory vomiting is mediated by the stimulation of chemotherapy drugs

Which of these is NOT a drug commonly used to prevent and treat chemotherapy-induced nausea and vomiting?

ACE inhibitors

Among the common adverse effects mentioned, which one is associated with Stevens-Johnson syndrome (SJS)?

Rash

Why are normal tissues like bone marrow, hair follicles, and intestinal epithelium susceptible to damage from cytotoxic drugs?

They are rapidly proliferating tissues.

What is the main reason for using combination chemotherapy in cancer treatment?

To enhance efficacy and minimize overlapping dose-limiting toxicity.

Which of the following is NOT a significant adverse effect associated with chemotherapy drugs?

Improved immune response

Why is it challenging to specifically target altered cancer cells with chemotherapy drugs?

Cancer cells have similar characteristics to normal human cells.

Which chemotherapy drug is known for its use in targeting B cells in certain cancers?

Busulfan

What is a common adverse effect associated with the chemotherapy drug Cisplatin?

Peripheral neuropathy

Test your knowledge on the toxicities associated with chemotherapy treatments, including symptoms like fever, chills, tachycardia, and hypotension. Learn about autoimmune complications and affected areas such as the endocrine system, skin, GI tract, pancreas, and lungs.

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