Chemotherapy and Antimicrobial Treatment Quiz

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What is the term chemotherapy used to describe?

The use of chemical substances to kill pathogenic organisms without injuring the host (correct)

The use of chemical substances to rid the body of malignant cells

The use of chemical substances to regulate heart function

The use of chemical substances to treat various aspects of disease

Which term refers to the utilization of chemical substances to treat microbial infections?

Antimicrobial chemotherapy (correct)

Antibiotic

Selective toxicity

Chemotherapeutic index

What is the ratio used to evaluate the toxicity of a drug?

Solubility ratio

Therapeutic index (correct)

Selective toxicity ratio

Antimicrobial index

What does the term 'antibiotic' refer to?

Chemical substances that inhibit the growth or destroy other microorganisms when used at low concentration Signup and view all the answers

What property should an ideal antimicrobial agent possess in terms of toxicity?

The toxic dosage level should be much higher than the effective therapeutic dosage level Signup and view all the answers

Which type of antimicrobial compounds are still commonly called antibiotics even though they are not natural substances?

Semisynthetic compounds Signup and view all the answers

Which of the following is a characteristic of antibiotics that would make them preferable for oral administration?

Resistance to metabolism and excretion Signup and view all the answers

What is the main difference between broad spectrum antibiotics and narrow spectrum antibiotics?

Broad spectrum antibiotics work against a wide range of microorganisms, while narrow spectrum antibiotics work against a specific group of microorganisms Signup and view all the answers

What is the significance of using narrow spectrum antibiotics when the microorganism is identified?

Narrow spectrum antibiotics reduce the possibility of developing resistance in microorganisms Signup and view all the answers

In what scenario would broad spectrum antibiotics be useful?

When the patient is seriously ill and the microbe is not identified Signup and view all the answers

How do beta lactam antibiotics act on bacterial cells?

They inhibit the synthesis of the peptidoglycan layer of bacterial cell walls Signup and view all the answers

What is the main mode of action of beta lactam antibiotics?

Inhibition of cell wall synthesis Signup and view all the answers

What is unique to beta lactam antibiotics in terms of their chemical structure?

Presence of a β-lactam ring Signup and view all the answers

Why do most bacteria have external rigid cell walls?

To withstand low osmotic pressure in body fluids Signup and view all the answers

What is the chemotherapeutic index used to evaluate?

The ratio between toxic dose and effective dose Signup and view all the answers

What is the main difference between narrow spectrum antibiotics and broad spectrum antibiotics?

Narrow spectrum antibiotics target specific types of bacteria, while broad spectrum antibiotics target a wide range of bacteria Signup and view all the answers

What is the significance of selective toxicity in antimicrobial agents?

It ensures that the drug harms the microbe without significant harm on the host Signup and view all the answers

What property should an ideal antimicrobial agent possess in terms of toxicity?

The toxic dosage level should be much higher than the effective therapeutic dosage level Signup and view all the answers

What is the term used to describe chemical substances produced by microorganisms that inhibit the growth or destroy other microorganisms when used at low concentration?

Antibiotic Signup and view all the answers

In antimicrobial chemotherapy, what does selective toxicity refer to?

Harming the microbe without significant harm on the host Signup and view all the answers

Which of the following is NOT a characteristic of an ideal antimicrobial agent?

Narrow spectrum of activity Signup and view all the answers

What is the primary mode of action of beta lactam antibiotics?

Inhibition of cell wall synthesis Signup and view all the answers

Why are broad spectrum antibiotics useful when the microorganism is not identified in a seriously ill patient?

They are effective against a wide range of microorganisms Signup and view all the answers

What is the role of the host immune system in the presence of bacteriostatic antibiotics?

Destroy and eliminate the microbe Signup and view all the answers

What is the significance of using narrow spectrum antibiotics when the microorganism is identified?

They reduce the possibility of producing resistance in microorganisms Signup and view all the answers

What is unique to beta lactam antibiotics in terms of their chemical structure?

'Irreversible' binding to transpeptidase enzymes Signup and view all the answers

Chemotherapy and Antimicrobial Treatment Quiz

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Questions and Answers

What is the term chemotherapy used to describe?

Which term refers to the utilization of chemical substances to treat microbial infections?

What is the ratio used to evaluate the toxicity of a drug?

What does the term 'antibiotic' refer to?

What property should an ideal antimicrobial agent possess in terms of toxicity?

Which type of antimicrobial compounds are still commonly called antibiotics even though they are not natural substances?

Which of the following is a characteristic of antibiotics that would make them preferable for oral administration?

What is the main difference between broad spectrum antibiotics and narrow spectrum antibiotics?

What is the significance of using narrow spectrum antibiotics when the microorganism is identified?

In what scenario would broad spectrum antibiotics be useful?

How do beta lactam antibiotics act on bacterial cells?

What is the main mode of action of beta lactam antibiotics?

What is unique to beta lactam antibiotics in terms of their chemical structure?

Why do most bacteria have external rigid cell walls?

What is the chemotherapeutic index used to evaluate?

What is the main difference between narrow spectrum antibiotics and broad spectrum antibiotics?

What is the significance of selective toxicity in antimicrobial agents?

What property should an ideal antimicrobial agent possess in terms of toxicity?

What is the term used to describe chemical substances produced by microorganisms that inhibit the growth or destroy other microorganisms when used at low concentration?

In antimicrobial chemotherapy, what does selective toxicity refer to?

Which of the following is NOT a characteristic of an ideal antimicrobial agent?

What is the primary mode of action of beta lactam antibiotics?

Why are broad spectrum antibiotics useful when the microorganism is not identified in a seriously ill patient?

What is the role of the host immune system in the presence of bacteriostatic antibiotics?

What is the significance of using narrow spectrum antibiotics when the microorganism is identified?

What is unique to beta lactam antibiotics in terms of their chemical structure?

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