Chemical Equilibrium and Reaction Coupling
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Questions and Answers

What is the primary function of a catalyst in a reaction?

  • Increase the activation energy
  • Change the nature of the reaction
  • Consumed by the reaction
  • Decrease the activation energy (correct)

Which statement about enzymes is true?

  • Enzymes increase activation energy
  • Enzymes are not specific for the reactions they catalyze
  • Enzymes change the nature of a reaction
  • Enzymes do not change ΔG for a reaction (correct)

What holds the enzyme-substrate complex together?

  • Hydrogen bonds, electrical attraction, or hydrophobic interactions (correct)
  • Covalent bonds only
  • Ionic interactions only
  • Van der Waals forces

What happens to enzymes in a reaction?

<p>Not consumed and can act repeatedly (A)</p> Signup and view all the answers

What is the function of the active site in an enzyme?

<p>Specifically bind to a substrate like a lock and key (B)</p> Signup and view all the answers

Which is NOT a property of enzymes?

<p>Change the nature of a reaction (B)</p> Signup and view all the answers

What is the role of enzymes regarding activation energy in reactions?

<p>Lower activation energy barrier (D)</p> Signup and view all the answers

'Induced fit' refers to what process in enzyme-catalyzed reactions?

<p>Enzymes changing shape upon substrate binding (B)</p> Signup and view all the answers

What is the main purpose of metabolic pathways?

<p>To control the sequence of enzymatically-controlled reactions (D)</p> Signup and view all the answers

What is the role of the commitment step in a metabolic pathway?

<p>It is the step that begins the sequence of reactions (D)</p> Signup and view all the answers

What is the purpose of feedback (negative) inhibition in a metabolic pathway?

<p>To shut down the pathway when the final product is abundant (A)</p> Signup and view all the answers

What is the relationship between metabolic pathways and homeostasis?

<p>Regulation of enzymes in metabolic pathways helps maintain homeostasis (C)</p> Signup and view all the answers

What is the key difference between reversible and irreversible enzyme inhibition?

<p>Irreversible inhibition permanently binds to the enzyme, while reversible does not (B)</p> Signup and view all the answers

How are metabolic reactions organized within cells?

<p>Metabolic reactions are organized into interconnected pathways (B)</p> Signup and view all the answers

What is the role of enzymes in metabolic pathways?

<p>Enzymes determine the order of reactions in a pathway (D)</p> Signup and view all the answers

How does feedback inhibition regulate the activity of a metabolic pathway?

<p>Feedback inhibition shuts down the pathway when the final product is abundant (B)</p> Signup and view all the answers

Which of the following statements about enzymes is NOT true?

<p>Enzymes increase the activation energy of a reaction by separating substrates (C)</p> Signup and view all the answers

At the point of saturation, what is the state of the enzyme and substrate?

<p>All enzyme molecules are bound to substrate molecules (B)</p> Signup and view all the answers

What is the primary role of an enzyme's active site?

<p>To bind the substrate(s) and stabilize the transition state (D)</p> Signup and view all the answers

Which of the following statements accurately describes the relationship between enzyme and substrate concentrations?

<p>Substrate concentration is usually much higher than enzyme concentration (C)</p> Signup and view all the answers

How is the efficiency of an enzyme typically measured?

<p>By the rate at which it can convert substrate to product (D)</p> Signup and view all the answers

What is the range of turnover rates for enzymes?

<p>1 to 40 million molecules per second (A)</p> Signup and view all the answers

Which of the following actions is performed by enzymes to facilitate a reaction?

<p>Enzymes orient substrate molecules, bringing together the atoms that will bond (B)</p> Signup and view all the answers

What is the primary function of an enzyme's active site during a reaction?

<p>To provide a template upon which the substrates are brought together in the proper position and orientation to react (A)</p> Signup and view all the answers

Which factor is NOT mentioned as a regulator of enzyme activity in the text?

<p>Pressure (D)</p> Signup and view all the answers

What happens to the noncovalent bonds in an enzyme at high temperatures?

<p>They begin to break, leading to denaturation of the enzyme (A)</p> Signup and view all the answers

What type of inhibitor binds to a site on the enzyme other than the active site?

<p>Non-competitive inhibitor (B)</p> Signup and view all the answers

What is the primary effect of nerve gas on the body?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is NOT a condition that can affect the secondary and tertiary structure of a protein?

<p>Presence of cofactors (C)</p> Signup and view all the answers

What is the term used to describe the loss of a protein's three-dimensional structure and function?

<p>Denaturation (C)</p> Signup and view all the answers

Which type of enzyme inhibitor covalently binds to the active site, permanently inactivating the enzyme?

<p>Irreversible inhibitor (C)</p> Signup and view all the answers

What is the primary function of enzyme inhibitors according to the text?

<p>To regulate metabolic pathways (B)</p> Signup and view all the answers

What is the relationship between the free energy change (G) and the point of equilibrium for a chemical reaction?

<p>The closer the reaction is to equilibrium, the more free energy is released. (C)</p> Signup and view all the answers

What is the purpose of coupling an endergonic reaction (G > 0) to an exergonic reaction (G < 0)?

<p>To make the endergonic reaction occur spontaneously. (B)</p> Signup and view all the answers

What is the relationship between the hydrolysis of ATP and the formation of glucose 6-phosphate in terms of free energy change (G)?

<p>The hydrolysis of ATP has a greater absolute value of G than the formation of glucose 6-phosphate. (C)</p> Signup and view all the answers

What is the role of enzymes in biological reactions?

<p>Enzymes decrease the activation energy of reactions. (B)</p> Signup and view all the answers

What is the relationship between chemical equilibrium and the forward and reverse reactions?

<p>At equilibrium, the forward and reverse reactions are balanced. (B)</p> Signup and view all the answers

What is the relationship between the free energy change (G) and the reversibility of a chemical reaction?

<p>Reactions with G values near zero are characteristic of readily reversible reactions. (A)</p> Signup and view all the answers

What is the purpose of the high-energy phosphate bond in ATP?

<p>The high-energy phosphate bond in ATP is used to activate endergonic processes. (C)</p> Signup and view all the answers

How do enzymes facilitate biologically important reactions?

<p>Enzymes decrease the activation energy of reactions, allowing them to occur more quickly. (D)</p> Signup and view all the answers

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