9 Questions
Which method of skin penetration enhancement involves the use of chemical enhancers?
Vesicular delivery
What is a characteristic of an ideal enhancer according to the text?
Predictable onset of action
Which enhancer can increase drug permeation by reversible alteration of the stratum corneum?
Azone
How can drug penetration through the skin be enhanced?
Block hydrogen bonding sites
What does an ideal enhancer need to be according to the text?
Non-irritant and inert
Which method of skin penetration enhancement disrupts the closely packed arrangement of the lipid bilayer?
Iontophoresis
How do chemical enhancers promote drug diffusion according to the text?
Control the stratum corneum
What is a disadvantage of transdermal drug delivery mentioned in the text?
Weak barrier for drug absorption
Which method can optimize the thermodynamic activity and partition coefficient of drugs for skin penetration enhancement?
Sonophoresis
Test your knowledge on chemical enhancers used to promote drug penetration and prevent loss of body content. Learn about the properties that make a chemical enhancer effective in topical formulations, such as compatibility with different drugs, solvent capacity, and cost considerations.
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