Chemical Carcinogenesis Terminology

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Questions and Answers

Which term refers to a physical or chemical agent that causes or induces malignant cells?

  • Carcinogen (correct)
  • Tumors
  • Genotoxic
  • Metastasis

What is the term for the spread of cancer beyond the organ of origin?

  • Genotoxic
  • Metastasis (correct)
  • Tumors
  • Nongenotoxic

Which type of carcinogens interact with DNA resulting in mutation?

  • Tumors
  • Genotoxic (correct)
  • Carcinogen
  • Nongenotoxic

What term is used for cancer cells that divide out of control and can invade and destroy nearby healthy tissue?

<p>Malignant tissue (D)</p> Signup and view all the answers

Which type of tissue has moderately increased cell growth but does not invade nearby tissue or spread to other parts of the body?

<p>Benign tissue (A)</p> Signup and view all the answers

What is the main cause of cancer according to the given text?

<p>Endogenous factors (B)</p> Signup and view all the answers

Which of the following was NOT reported as a linkage with cancer in the history of chemical carcinogenesis?

<p>Exposure to asbestos (B)</p> Signup and view all the answers

Which of the following is an example of an exogenous carcinogen as per the text?

<p>Smoking (D)</p> Signup and view all the answers

In the multistage nature of chemical carcinogenesis, which stage involves the selective clonal expansion of the initiated cell to form a focal lesion?

<p>Promotion (A)</p> Signup and view all the answers

Which type of agents are bile acids and free oxygen radicals as mentioned in the text?

<p>Endogenous carcinogens (C)</p> Signup and view all the answers

What is genetic toxicology primarily concerned with?

<p>Examining changes in DNA molecules of cells due to various factors (C)</p> Signup and view all the answers

Which of the following is NOT a form of genetic damage covered by genetic toxicity?

<p>RNA synthesis (D)</p> Signup and view all the answers

What does the central dogma of molecular biology describe?

<p>Flow of genetic information within a biological system (D)</p> Signup and view all the answers

What are the building blocks of nucleic acids?

<p>Nucleotides (C)</p> Signup and view all the answers

What does genetic toxicology consider as a general term covering damage such as clastogenicity and aneuploidy?

<p>Genotoxicity (B)</p> Signup and view all the answers

What is the main function of DNA in living organisms?

<p>Storing and carrying genetic instructions (A)</p> Signup and view all the answers

Where are chromosomes located in the cell?

<p>In the cell nucleus (C)</p> Signup and view all the answers

What is a gene made up of?

<p>DNA (C)</p> Signup and view all the answers

What is the role of mutagens?

<p>Inducing changes in DNA called mutations (C)</p> Signup and view all the answers

Which term refers to changes caused by some factors in the genetic material in the cell nucleus?

<p>Mutation (B)</p> Signup and view all the answers

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