Chemical Carcinogenesis Terminology

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Which term refers to a physical or chemical agent that causes or induces malignant cells?

Carcinogen

What is the term for the spread of cancer beyond the organ of origin?

Metastasis

Which type of carcinogens interact with DNA resulting in mutation?

Genotoxic

What term is used for cancer cells that divide out of control and can invade and destroy nearby healthy tissue?

Malignant tissue

Which type of tissue has moderately increased cell growth but does not invade nearby tissue or spread to other parts of the body?

Benign tissue

What is the main cause of cancer according to the given text?

Endogenous factors

Which of the following was NOT reported as a linkage with cancer in the history of chemical carcinogenesis?

Exposure to asbestos

Which of the following is an example of an exogenous carcinogen as per the text?

Smoking

In the multistage nature of chemical carcinogenesis, which stage involves the selective clonal expansion of the initiated cell to form a focal lesion?

Promotion

Which type of agents are bile acids and free oxygen radicals as mentioned in the text?

Endogenous carcinogens

What is genetic toxicology primarily concerned with?

Examining changes in DNA molecules of cells due to various factors

Which of the following is NOT a form of genetic damage covered by genetic toxicity?

RNA synthesis

What does the central dogma of molecular biology describe?

Flow of genetic information within a biological system

What are the building blocks of nucleic acids?

Nucleotides

What does genetic toxicology consider as a general term covering damage such as clastogenicity and aneuploidy?

Genotoxicity

What is the main function of DNA in living organisms?

Storing and carrying genetic instructions

Where are chromosomes located in the cell?

In the cell nucleus

What is a gene made up of?

DNA

What is the role of mutagens?

Inducing changes in DNA called mutations

Which term refers to changes caused by some factors in the genetic material in the cell nucleus?

Mutation

Test your knowledge on the terminology related to chemical carcinogenesis and cancer. Learn about the abnormal cell growth, mutation, and proliferation that characterizes this disease, which is a significant cause of mortality worldwide.

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