Chemical Aspects of Formulation Lecture Quiz
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Questions and Answers

Which factor can significantly affect oral drug absorption?

  • Crystallization of the drug
  • The pH of gastrointestinal fluids (correct)
  • The rheology of the drug
  • The physical properties of the drug

What is the main aspect affected by crystallization of a drug?

  • Drug release
  • Drug stability
  • Intestinal permeability
  • Drug solubility (correct)

Which characteristic can alter the pharmacokinetics and pharmacodynamics of a drug?

  • The surface tension and wetting properties of the drug
  • The removal of specific functional groups in a drug (correct)
  • The adhesion and adsorption properties of the drug
  • The range of pH in body fluids

What does clinical pharmaceutics aim to provide to the pharmacist?

<p>Understanding of the physical properties of dosage forms (A)</p> Signup and view all the answers

What initiates the biochemical and physiological changes that are characteristic of a drug's response?

<p>The introduction of specific functional groups in the drug (B)</p> Signup and view all the answers

Which type of stones develop in alkaline urine?

<p>Calcium phosphate, calcium carbonate, and magnesium phosphate (C)</p> Signup and view all the answers

What is the pH range for alkaline water?

<p>9.5-11 (A)</p> Signup and view all the answers

Which drugs are effective in treating urinary tract infections if the urine is alkaline?

<p>Streptomycin, neomycin, and kanamycin (B)</p> Signup and view all the answers

What can cause the formation of renal stones?

<p>High urine pH (C)</p> Signup and view all the answers

Which medication resulted in the precipitation of needle-like crystals consistent with acyclovir in the patient's urine?

<p>Emtricitabine (B)</p> Signup and view all the answers

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