Podcast
Questions and Answers
What is the primary function of C3b in the complement system?
What is the primary function of C3b in the complement system?
- To cleave C5 into C5a and C5b
- To directly bind to the cell surface and tag it for phagocytosis (correct)
- To activate the assembly of the membrane attack complex (MAC)
- To act as a chemoattractant
Which of the following is a key step in the construction of the membrane attack complex (MAC)?
Which of the following is a key step in the construction of the membrane attack complex (MAC)?
- C5b attaches to the cell and allows activation and assembly of C6, C7, C8, and C9 (correct)
- C3b binds directly to the cell surface
- C5 convertase cleaves C5 into C5a and C5b
- C3a acts as a chemoattractant
What is the main function of the major histocompatibility complex (MHC) molecules?
What is the main function of the major histocompatibility complex (MHC) molecules?
- To code for enzymes and structural molecules needed for activation and function of B and T cells
- To directly bind to the cell surface and tag it for phagocytosis
- To act as chemoattractants and facilitate cellular communication
- To bind to T cell receptors and present peptides for recognition (correct)
Which of the following is a key difference between MHC class I and MHC class II molecules?
Which of the following is a key difference between MHC class I and MHC class II molecules?
What is the primary function of T cell receptors (TCRs)?
What is the primary function of T cell receptors (TCRs)?
Which of the following is a key feature of the T cell receptor (TCR)?
Which of the following is a key feature of the T cell receptor (TCR)?
What is the primary function of cytokines in the immune response?
What is the primary function of cytokines in the immune response?
Which of the following is a key difference between CD4+ and CD8+ T cells?
Which of the following is a key difference between CD4+ and CD8+ T cells?
What is the primary function of the CD3 complex associated with the T cell receptor (TCR)?
What is the primary function of the CD3 complex associated with the T cell receptor (TCR)?
What is the main function of immunoglobulins?
What is the main function of immunoglobulins?
How many polypeptide chains are present in the basic monomeric structure of immunoglobulins?
How many polypeptide chains are present in the basic monomeric structure of immunoglobulins?
Which domain contains a variable domain and 1 or more constant domains in the Light chain of immunoglobulins?
Which domain contains a variable domain and 1 or more constant domains in the Light chain of immunoglobulins?
How many types of H chains determine the Class (Isotype) of immunoglobulins?
How many types of H chains determine the Class (Isotype) of immunoglobulins?
Where are the antigen-binding sites located on an immunoglobulin molecule?
Where are the antigen-binding sites located on an immunoglobulin molecule?
How many domains do Light chains have in an immunoglobulin monomer?
How many domains do Light chains have in an immunoglobulin monomer?
What is the main role of the Hinge Region in an immunoglobulin molecule?
What is the main role of the Hinge Region in an immunoglobulin molecule?
Which molecule is associated with the T-cell receptor (TCR) and involved in signaling once the TCR is engaged?
Which molecule is associated with the T-cell receptor (TCR) and involved in signaling once the TCR is engaged?
Which immunoglobulin class is mainly responsible for activating complement through the Classical Pathway?
Which immunoglobulin class is mainly responsible for activating complement through the Classical Pathway?
How many subclasses does Immunoglobulin A (IgA) have?
How many subclasses does Immunoglobulin A (IgA) have?
Which type of cells recognize MHC class II molecules on cells?
Which type of cells recognize MHC class II molecules on cells?
Which immunoglobulin can cross the placenta?
Which immunoglobulin can cross the placenta?
What is the mechanism by which the immune system avoids constantly responding to self-antigens and innocuous environmental antigens?
What is the mechanism by which the immune system avoids constantly responding to self-antigens and innocuous environmental antigens?
What is the state of lymphocyte unresponsiveness called?
What is the state of lymphocyte unresponsiveness called?
Which immunoglobulin class is primarily involved in immediate hypersensitivity reactions?
Which immunoglobulin class is primarily involved in immediate hypersensitivity reactions?
Which of the following is NOT a reason for the presence of antibodies to a specific pathogen?
Which of the following is NOT a reason for the presence of antibodies to a specific pathogen?
Which immunoglobulin class is the main Ig of the secondary response?
Which immunoglobulin class is the main Ig of the secondary response?
How many antigen-binding sites does Immunoglobulin M (IgM) have?
How many antigen-binding sites does Immunoglobulin M (IgM) have?
Which type of immunodiagnostic procedure is used to detect either antigens or antibodies in clinical specimens?
Which type of immunodiagnostic procedure is used to detect either antigens or antibodies in clinical specimens?
Which immunoglobulin class is found mainly as a monomer on nave B cells?
Which immunoglobulin class is found mainly as a monomer on nave B cells?
What type of molecules permit cellular communication and provide stable cell-to-cell contact?
What type of molecules permit cellular communication and provide stable cell-to-cell contact?
Which of the following statements about T and B cells is correct?
Which of the following statements about T and B cells is correct?
What percentage of serum Igs does Immunoglobulin D (IgD) represent?
What percentage of serum Igs does Immunoglobulin D (IgD) represent?
Which type of cells recognize MHC class I molecules on cells?
Which type of cells recognize MHC class I molecules on cells?
Which of the following is NOT a result of the classical pathway of complement activation?
Which of the following is NOT a result of the classical pathway of complement activation?
Which of the following statements about the C1 complex is correct?
Which of the following statements about the C1 complex is correct?
What is the role of the C4b2b3b complex in the classical complement pathway?
What is the role of the C4b2b3b complex in the classical complement pathway?
Which of the following events occurs first in the classical complement pathway?
Which of the following events occurs first in the classical complement pathway?
Which of the following immunoglobulins can initiate the classical complement pathway when bound to an antigen?
Which of the following immunoglobulins can initiate the classical complement pathway when bound to an antigen?
What is the role of the C3a and C5a components in the classical complement pathway?
What is the role of the C3a and C5a components in the classical complement pathway?
Which of the following statements about the classical complement pathway is correct?
Which of the following statements about the classical complement pathway is correct?
Which of the following events occurs during the classical complement pathway?
Which of the following events occurs during the classical complement pathway?
What is the role of the C4b2b complex in the classical complement pathway?
What is the role of the C4b2b complex in the classical complement pathway?
