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Chapter 17: Hematologic Systems - Microcytic Anemia Causes

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30 Questions

Which blood cell type does not contain a nucleus?

Erythrocytes (RBCs)

What stimulates the process of erythropoiesis?

Erythropoietin (EPO)

In which part of the body does the greatest bone marrow activity occur in adults?

Vertebrae

What is the most common symptom associated with a rapid onset of anemia?

Confusion

Which test is commonly used for diagnosing anemia by assessing the number of red blood cells?

Complete blood count (CBC)

Where does the process of erythropoiesis originate?

Bone marrow

Which component is responsible for carrying oxygen from the lungs to the body?

Erythrocytes (RBCs)

What is the lifespan of erythrocytes (RBCs)?

120 days

Which cell type originates from the same stem cell as platelets and white blood cells?

Neutrophils

Which hormone is produced in response to low blood oxygen levels to stimulate red blood cell production?

Erythropoietin (EPO)

Which of the following is not an extrinsic cause of hemolysis?

Thalassemia

In which type of hemolysis does the breakdown of red blood cells occur in the vasculature?

Intravascular

What condition is associated with normocytic anemia according to the text?

Sickle cell disease

Which of the following is a symptom of sickle cell disease, according to the text?

Aseptic bone necrosis

What is the primary function of blood clotting factors in the hematologic system?

Clotting

Which of the following is not a symptom of sickle cell disease?

Night blindness

What is a common trigger for sickle cell crisis mentioned in the text?

Stress

Where does hemolysis occur in extravascular hemolysis?

In liver

Which of the following conditions is not caused by a defect in RBC metabolism?

Immune-mediated hemolysis

What type of hemolysis involves the presence of hemosiderin deposits in certain organs?

Extravascular

Which type of anemia is characterized by the presence of ringed sideroblasts?

Sideroblastic anemia

Which type of anemia is more common in the Mediterranean area?

Thalassemia

Which of the following is not a cause of macrocytic anemia?

Iron deficiency

What is the test used to diagnose pernicious anemia?

Intrinsic factor antibody test

Which type of anemia may confer some level of protection against malaria?

Thalassemia

What is the main cause of macrocytic anemia due to an inability to absorb B12?

Lack of intrinsic factor

Which type of anemia is characterized by abnormally large RBCs that don't function appropriately?

Megaloblastic anemia

What is the content of the ringed sideroblasts in sideroblastic anemia?

Granules of iron in mitochondria

In which type of anemia do you observe nucleated erythroblasts with iron-laden mitochondria surrounding the nucleus?

Sideroblastic anemia

Which lab values are typically low in sideroblastic anemia?

MCV and TIBC

Explore the causes of microcytic anemia within the hematologic system, including iron deficiency anemia, sideroblastic anemia, lead poisoning, and thalassemia. Learn about the role of iron in hemoglobin production and its absorption, transportation, and storage in the body.

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