18 Questions
What is the most significant implication of the Watson-Crick model regarding DNA replication?
It suggests a mechanism for cells to replicate their genetic information
How are two strands of DNA held together in the double helix structure?
By hydrogen bonds
What happens during DNA denaturation?
DNA strands are separated
What is the purpose of treating DNA with an alkaline solution like NaOH?
To denature the DNA strands
What is the maximal absorbance wavelength for all DNA molecules, whether double-stranded or single-stranded?
260nm
What does the DNA melting temperature (Tm) represent?
The temperature at which one-half of the absorbance change has been achieved
What is the approximate diameter of isolated chromatin?
10 nm
Which structure is formed by the packing together of 30-nm chromatin fibers in an irregular, three-dimensional zigzag structure?
Chromatin fibers
Which type of DNA sequences in the human genome are mostly non-coding?
Tandem repeats
What do the loops in the chromatin loops mainly contain?
Active regions of DNA
Which element is a type of interspersed repeat present in eukaryotic genomes?
SINEs
What is responsible for the spatial arrangement of the looped domains through attachment to nonhistone proteins forming a chromosomal scaffold?
Histones
What is the term used to describe the basic unit of DNA packaging, consisting of DNA wrapped around a core of histone proteins?
Nucleosome
Which protein type is responsible for the compact nature of DNA in eukaryotic cells by forming the core around which DNA is wrapped?
Histones
In eukaryotic cells, what is the structure formed when nucleosomes are further coiled and condensed to achieve higher levels of DNA packaging?
Chromatid
What is the primary function of DNA condensation in eukaryotic cells?
To reduce DNA accessibility for transcription
Which of the following statements accurately describes the role of nucleosomes in regulating gene expression?
Nucleosomes hinder access to DNA, inhibiting gene expression.
Which of the following components play a crucial role in maintaining the organization and structure of chromosomes during cell division?
Spindle fibers
Test your knowledge on DNA properties, chromosome structure, eukaryotic chromosomes, nucleus features, DNA packaging in cells, and the structure of DNA according to the Watson-Crick model.
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