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Questions and Answers
Which of the following statements about aldosterone is NOT correct?
Which of the following statements about aldosterone is NOT correct?
ADH (antidiuretic hormone) is released by the posterior pituitary gland.
ADH (antidiuretic hormone) is released by the posterior pituitary gland.
True
What is the osmolarity of the filtrate at the end of the proximal tubule?
What is the osmolarity of the filtrate at the end of the proximal tubule?
isotonic - 300 mOsm
In overhydration, what would be the levels of ADH and the osmolarity of the urine?
In overhydration, what would be the levels of ADH and the osmolarity of the urine?
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In severe dehydration or blood loss, what would be the levels of ADH and the urine flow rate?
In severe dehydration or blood loss, what would be the levels of ADH and the urine flow rate?
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Most solutes that are reabsorbed in the proximal convoluted tubule use which pathway?
Most solutes that are reabsorbed in the proximal convoluted tubule use which pathway?
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During reabsorption of water in the proximal convoluted tubule, what causes water to osmose from the lumen into the interstitial space?
During reabsorption of water in the proximal convoluted tubule, what causes water to osmose from the lumen into the interstitial space?
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The decreased intracellular concentration of sodium in tubular cells during active transport is caused by which mechanism?
The decreased intracellular concentration of sodium in tubular cells during active transport is caused by which mechanism?
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The active transport of which ion out of proximal convoluted tubule cells causes the reabsorption of both water and solutes?
The active transport of which ion out of proximal convoluted tubule cells causes the reabsorption of both water and solutes?
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Which transporters in the luminal membrane result in secretion?
Which transporters in the luminal membrane result in secretion?
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What is the limiting factor for the reabsorption of most actively transported solutes in the proximal tubule?
What is the limiting factor for the reabsorption of most actively transported solutes in the proximal tubule?
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What triggers the movement of water out of the descending limb?
What triggers the movement of water out of the descending limb?
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What would be the effect of blocking the hormone that works at the points indicated by the red arrows?
What would be the effect of blocking the hormone that works at the points indicated by the red arrows?
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Which hormones cause the kidney to increase the body's content of sodium?
Which hormones cause the kidney to increase the body's content of sodium?
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Antidiuretic hormone (ADH) causes __________.
Antidiuretic hormone (ADH) causes __________.
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The ability to form concentrated urine depends on the functions of?
The ability to form concentrated urine depends on the functions of?
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The mechanism for producing concentrated urine involves which of the following?
The mechanism for producing concentrated urine involves which of the following?
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Antidiuretic hormone increases the permeability of the collecting ducts to water.
Antidiuretic hormone increases the permeability of the collecting ducts to water.
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A drug that inhibits angiotensin converting enzyme (ACE) may lead to which of the following?
A drug that inhibits angiotensin converting enzyme (ACE) may lead to which of the following?
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Which substances are not normally found in the filtrate?
Which substances are not normally found in the filtrate?
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Filtrate in the proximal convoluted tubule normally contains:
Filtrate in the proximal convoluted tubule normally contains:
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When the level of ADH decreases, what happens to the osmolarity of the urine?
When the level of ADH decreases, what happens to the osmolarity of the urine?
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Which area is sensitive to the hormone ADH?
Which area is sensitive to the hormone ADH?
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Where does most nutrient reabsorption occur?
Where does most nutrient reabsorption occur?
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Which area is sensitive to aldosterone?
Which area is sensitive to aldosterone?
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The ureters extend from the __________.
The ureters extend from the __________.
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Study Notes
Hormones and Regulation
- Aldosterone increases sodium reabsorption by raising Na+-K+ ATPase pumps in the proximal tubule.
- Antidiuretic hormone (ADH) is released from the posterior pituitary gland and acts on the kidneys.
- Aldosterone causes the kidneys to increase sodium content in the body.
- ADH decreases urine volume while increasing the concentration of solutes in the urine.
Urine Concentration and Filtration
- The osmolarity of the filtrate at the end of the proximal tubule is isotonic at 300 mOsm.
- Overhydration results in low ADH levels and urine osmolarity of 100 mOsm, leading to dilute urine.
- Severe dehydration produces high ADH levels and a low urine flow rate of 0.25 ml/min.
- The ability to form concentrated urine depends on the loop of Henle and the collecting duct's function.
Transport Mechanisms
- Most solutes in the proximal convoluted tubule are reabsorbed via transcellular pathways.
- Water reabsorption in the proximal convoluted tubule occurs due to increased osmolarity in the interstitial fluid.
- The active transport of sodium out of proximal tubular cells aids solute and water reabsorption, with sodium-potassium ATPase responsible for maintaining low intracellular sodium.
- Na+-H+ countertransport in the luminal membrane leads to the secretion of hydrogen ions.
Limitations and Effects
- The limiting factor for the reabsorption of actively transported solutes is the number of transport carriers in the luminal membrane.
- Inhibition of hormones acting at specific points in tubule function can lead to increased dilute urine production.
- Blocking ADH results in decreased urine osmolarity as water reabsorption is lessened.
Filtrate Composition
- Normal filtrate in the proximal convoluted tubule contains nutrients, urea, hydrogen ions, and water.
- Proteins are not normally present in the filtrate.
Drug Effects
- Inhibitors of angiotensin converting enzyme (ACE) can lead to less aldosterone secretion, increased sodium loss through urine, and reduced blood pressure.
Sensitivity and Reabsorption Sites
- Areas sensitive to ADH are located in specified parts of the nephron.
- The primary site for nutrient reabsorption is located in the proximal convoluted tubule.
- The area sensitive to aldosterone is also specific to certain nephron segments.
Ureter Facts
- The ureters transport urine from the renal pelvis to the urinary bladder.
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Description
Test your knowledge on Chapter 26 of Mastering Anatomy and Physiology with this quiz. The questions focus on key concepts such as aldosterone, ADH, and osmolarity. Perfect for students preparing for exams in anatomy and physiology.