Cervical Inflammation and Infections
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Questions and Answers

What is the usual clinical consequence of cervical inflammation in women?

  • Significant acute cervicitis
  • Chronic cervicitis
  • Upper genital tract disease
  • Little clinical consequence (correct)

    • What is the composition of cervical polyps?

  • Fibromuscular stroma with scant glands
  • Compact epithelial proliferation
  • Loose fibrous stroma with dilated mucus-secreting endocervical glands (correct)
  • Dense fibrous stroma with rare glands

    • What is the cause of microglandular hyperplasia of the cervix?

  • Infections by gonococci
  • Progestin administration (correct)
  • Hormonal imbalance during menstruation
  • Hypertension during pregnancy

    • At what age does the incidence of cervical cancer peak?

    <p>45 years</p> Signup and view all the answers

    What is the significance of identifying cervical inflammation with gonococci, chlamydiae, mycoplasmas, and herpes simplex virus?

    <p>Sexual transmission and upper genital tract disease</p> Signup and view all the answers

    What is the characteristic of benign exophytic growths of the cervix?

    <p>Soft, mucoid lesions</p> Signup and view all the answers

    What is the characteristic of CIN3?

    <p>Atypical cells involving the whole thickness of the epithelium</p> Signup and view all the answers

    What percentage of Embryonal rhabdomyosarcoma cases occur under 5 years of age?

    <p>90%</p> Signup and view all the answers

    What is the precursor lesion for invasive adenocarcinoma?

    <p>Adenocarcinoma In Situ (AIS)</p> Signup and view all the answers

    What is the characteristic of squamous cell carcinomas in cervical carcinoma?

    <p>Either keratinizing or nonkeratinizing</p> Signup and view all the answers

    What is the typical appearance of Embryonal rhabdomyosarcoma on gross examination?

    <p>A large, reddish, soft mass</p> Signup and view all the answers

    What is the primary site of HPV infection in the cervix?

    <p>Immature basal cells of the squamous epithelium</p> Signup and view all the answers

    What is the most common type of cervical carcinoma?

    <p>Squamous cell carcinoma</p> Signup and view all the answers

    What is the characteristic of the malignant cells in Embryonal rhabdomyosarcoma?

    <p>Small cells with oval nuclei</p> Signup and view all the answers

    Which of the following is a risk factor for cervical cancer?

    <p>Having a partner with a sexually transmitted disease</p> Signup and view all the answers

    What is the consequence of HPV DNA integration in cervical cells?

    <p>Interference with p53 and RB genes</p> Signup and view all the answers

    What is the association of cervical inflammation with upper genital tract disease?

    <p>It is a significant association</p> Signup and view all the answers

    What is the diagnosis for a cervical biopsy specimen with atypical dysplastic squamous epithelial cells in the lower one-third of the epithelium and no invasion into the underlying tissue?

    <p>Cervical intraepithelial neoplasia grade III</p> Signup and view all the answers

    What is the aetiological factor responsible for cervical intraepithelial neoplasia?

    <p>Infection by human papilloma virus</p> Signup and view all the answers

    What is the type of cervical cancer that arises from the squamous epithelium?

    <p>Squamous Cell Carcinoma</p> Signup and view all the answers

    What is the typical location of endocervical polyps?

    <p>Endocervix</p> Signup and view all the answers

    What is the characteristic of invasive carcinoma in the cervix?

    <p>Break of the epithelial basement membrane at any point</p> Signup and view all the answers

    What is the characteristic of endocervical polyps?

    <p>Soft, mucoid lesions</p> Signup and view all the answers

    What is the percentage of cervical carcinoma cases that are adenocarcinoma?

    <p>15%</p> Signup and view all the answers

    Study Notes

    Cervical Inflammation

    • Found in almost all women, but usually has little clinical consequence.
    • Can be caused by infections such as gonococci, chlamydiae, mycoplasmas, and herpes simplex virus, leading to acute or chronic cervicitis.
    • Important to identify association with upper genital tract disease, complications during pregnancy, and sexual transmission.

    Benign Exophytic Growths

    • Arise from the endocervix.
    • Cause irregular vaginal bleeding.
    • Characterized as soft, mucoid lesions composed of loose fibrous stroma containing dilated, mucus-secreting endocervical glands, often accompanied by inflammation.

    Endocervical Polyps

    • Benign condition characterized by closely packed proliferation of endocervical glands without intervening stroma.
    • Caused by progestin administration, such as during pregnancy, postpartum period, or oral contraceptive pills administration.

    Premalignant and Malignant Neoplasms of the Uterine Cervix

    • One of the most common cancers in females, especially in developing countries.
    • Peak incidence occurs at 45 years of age.

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    Description

    This quiz covers the causes and effects of cervical inflammation, including infections by various pathogens and their associations with upper genital tract disease and complications during pregnancy.

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