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Questions and Answers
What is the most accurate method for triaging women with atypical squamous cells of undetermined significance (ASC-US)?
What is the most accurate method for triaging women with atypical squamous cells of undetermined significance (ASC-US)?
- Dual staining (p16/Ki-67)
- p16 staining
- Ki-67 testing
- High-risk human papillomavirus (hrHPV) testing (correct)
What indicates neoplastic transformation of human papillomavirus–infected cervical cells?
What indicates neoplastic transformation of human papillomavirus–infected cervical cells?
- Overexpression of p16, with or without Ki-67 (correct)
- Cervical intraepithelial neoplasia of grade 3 or worse (CIN3+)
- Low-grade squamous intraepithelial lesion (LSIL)
- hrHPV testing
What did the literature search focus on?
What did the literature search focus on?
- Women with LSIL triaged with hrHPV testing
- Women with ASC-US or LSIL
- Women with high-risk human papillomavirus (hrHPV)
- Women with ASC-US or LSIL triaged with dual staining (p16/Ki-67) and/or p16 staining (correct)
What did the studies indicate about the specificity of hrHPV testing for triaging low-grade squamous intraepithelial lesion (LSIL)?
What did the studies indicate about the specificity of hrHPV testing for triaging low-grade squamous intraepithelial lesion (LSIL)?
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How many studies were eligible in the literature search conducted?
How many studies were eligible in the literature search conducted?
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