Cervical Cancer Screening and Triage Quiz
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Questions and Answers

What is the most accurate method for triaging women with atypical squamous cells of undetermined significance (ASC-US)?

  • Dual staining (p16/Ki-67)
  • p16 staining
  • Ki-67 testing
  • High-risk human papillomavirus (hrHPV) testing (correct)

    • What indicates neoplastic transformation of human papillomavirus–infected cervical cells?

  • Overexpression of p16, with or without Ki-67 (correct)
  • Cervical intraepithelial neoplasia of grade 3 or worse (CIN3+)
  • Low-grade squamous intraepithelial lesion (LSIL)
  • hrHPV testing

    • What did the literature search focus on?

  • Women with LSIL triaged with hrHPV testing
  • Women with ASC-US or LSIL
  • Women with high-risk human papillomavirus (hrHPV)
  • Women with ASC-US or LSIL triaged with dual staining (p16/Ki-67) and/or p16 staining (correct)

    • What did the studies indicate about the specificity of hrHPV testing for triaging low-grade squamous intraepithelial lesion (LSIL)?

    <p>Very low specificity (D)</p> Signup and view all the answers

    How many studies were eligible in the literature search conducted?

    <p>Thirty-eight studies (A)</p> Signup and view all the answers

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