Cerebrospinal Fluid Components in CNS Infections Quiz
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Questions and Answers

What is one method that can be used to overcome problems of CSF penetration for antibiotic therapy in bacterial meningitis?

  • Increasing the dosage of oral antibiotics
  • Using antiviral medications
  • Direct instillation of antibiotics intravenously
  • Direct instillation of antibiotics intrathecally (correct)
  • What should antibiotic therapy be tailored to once a pathogen is identified in bacterial meningitis?

  • The geographic location
  • The patient's gender
  • The patient's age
  • The specific pathogen (correct)
  • In cases where shunt infections are difficult to eradicate, what type of delivery method may be necessary for antibiotic treatment?

  • Direct instillation of antibiotics intraventricularly (correct)
  • Intravenous delivery of antibiotics
  • Oral delivery of antibiotics
  • Inhalation of antibiotics
  • Which antimicrobial agent listed in Table 4 is considered an alternative for the treatment of meningitis caused by gram-negative microorganisms?

    <p>Tazobactam</p> Signup and view all the answers

    Which pathogen has been successfully treated with 10–14 days of antibiotic therapy in cases of meningitis?

    <p>S.pneumoniae</p> Signup and view all the answers

    Which of the following is NOT typically associated with young children presenting with bacterial meningitis?

    <p>Photophobia</p> Signup and view all the answers

    Which skin lesions are typically seen in meningococcal meningitis?

    <p>Purpuric and petechial lesions</p> Signup and view all the answers

    How can changes in cerebrospinal fluid (CSF) fluid be used in the diagnosis of meningitis?

    <p>By analyzing changes in CSF protein content</p> Signup and view all the answers

    Why may CSF culture be considered the gold standard for diagnosing bacterial meningitis?

    <p>It directly identifies the bacteria causing the infection</p> Signup and view all the answers

    What effect can prior antibiotic therapy have on Gram stain and CSF culture in diagnosing bacterial meningitis?

    <p>It renders Gram stain and CSF culture negative</p> Signup and view all the answers

    When might polymerase chain reaction (PCR) techniques be particularly useful in diagnosing central nervous system (CNS) infections?

    <p>In patients who have received antimicrobial therapy before lumbar puncture</p> Signup and view all the answers

    What is the key goal of pharmacologic therapy in CNS infections?

    <p>Initiating appropriate antimicrobials</p> Signup and view all the answers

    What is the significance of a lymphocytic predominance becoming neutrophilic during antituberculous treatment?

    <p>It suggests a therapeutic paradox</p> Signup and view all the answers

    What should be done if a patient presents with possible CNS infection?

    <p>Immediate administration of antipyretics</p> Signup and view all the answers

    What is the recommended duration for antimicrobial therapy in suspected bacterial meningitis cases?

    <p>48-72 hours</p> Signup and view all the answers

    What is the time limit from suspected diagnosis to initiation of antibiotic treatment for CNS infections?

    <p>1 hour</p> Signup and view all the answers

    Which of the following is considered a key element in the treatment of CNS infections?

    <p>Fluid administration</p> Signup and view all the answers

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