Cerebellum Anatomy
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Questions and Answers

Which axons are the only ones to leave the cortex to medulla in the cerebellum?

  • Axons of red nucleus
  • Axons of Purkinje cells (correct)
  • Axons of deep cerebellar nuclei
  • Axons of vestibular nuclei
  • What is the primary destination of the main efferent fibers from the cerebellum?

  • Vestibular nuclei and red nucleus (correct)
  • Deep cerebellar nuclei and cortex
  • Ventral lateral nucleus of thalamus and cortex
  • Spinal cord and peripheral nervous system
  • Which zone of the cerebellum is concerned with the planning of sequential movements of the entire body?

  • Vermis
  • Lateral zone (correct)
  • Intermediate zone
  • Deep cerebellar nuclei
  • What is the clinical implication of a cerebellar lesion on muscle tone?

    <p>Hypotonia</p> Signup and view all the answers

    Which of the following is a characteristic of a patient with a cerebellar lesion during gait?

    <p>Wide base of support</p> Signup and view all the answers

    What is the term for the disturbance of reflexes in a patient with a cerebellar lesion?

    <p>Pendular knee jerk</p> Signup and view all the answers

    Which test is used to assess dysdiadochokinesia in a patient with a cerebellar lesion?

    <p>Supination and pronation test</p> Signup and view all the answers

    What is the main function of the intermediate zone of the cerebellum?

    <p>Control of muscles of distal parts of limbs</p> Signup and view all the answers

    Which nuclei are the primary origin of the efferent fibers from the cerebellum?

    <p>Deep cerebellar nuclei</p> Signup and view all the answers

    What is the characteristic of the patient's posture in a cerebellar lesion?

    <p>Shoulder on the side of lesion is lower</p> Signup and view all the answers

    Study Notes

    Cerebellum Structure and Connections

    • Originated from the hindbrain, separated from pons and medulla by the fourth ventricle
    • Connected to the brain stem by inferior, middle, and superior cerebellar peduncles

    External Features

    • Consists of two cerebellar hemispheres joined in midline by the vermis
    • Surface is highly convoluted, forming folia separated by fissures

    Anatomical Subdivisions

    • Anterior lobe: lies above the V-shaped primary fissure
    • Posterior (middle) lobe: between primary fissure and uvulonodular fissure
    • Flocculonodular lobe: posterior to uvulonodular fissure
    • Superior and inferior surfaces: separated by a horizontal fissure

    Constituents

    • Outer grey matter: cerebellar cortex
    • Inner white matter: cerebellar medulla has 4 masses of grey matter embedded in it

    Cerebellar Cortex

    • Divided into 3 layers:
      • Molecular layer: stellate cells, basket cells, scattered between branches of nerve cells
      • Purkinje cell layer: large golgi type 1 neurons
      • Granular layer: granule cells, golgi type II neurons

    Cerebellar Nuclei

    • Four masses of grey matter:
      • Dentate nucleus
      • Emboliform nucleus
      • Globose nucleus
      • Fastigial nucleus

    Fibers in White Matter

    • 3 types:
      • Intrinsic fibers
      • Afferent fibers
      • Efferent fibers

    Afferent Fibers

    • Corticopontocerebellar: from frontal, parietal, temporal, and occipital lobes
    • Cerebroolivocerebellar: from inferior olivary nuclei
    • Cerebroreticulocerebellar: from sensorimotor areas
    • From spinal cord: anterior spinocerebellar and posterior spinocerebellar

    Cerebellar Medulla

    • Axons of Purkinje cells are the only axons to leave the cortex
    • Most axons do not leave the cerebellum and end in deep cerebellar nuclei
    • Efferent fibers mainly go to vestibular nuclei, red nucleus, and ventral lateral nucleus of thalamus

    Functional Subdivisions of the Cerebellum

    • Cortex of vermis influences movements of long axis of body
    • Intermediate zone controls muscles of distal parts of limbs
    • Lateral zone involved with planning of sequential movements and conscious assessment of movement errors

    Clinical Implications

    • Hypotonia: postural changes and alteration of gait
    • Ataxia: tremors, decomposition of movements, and disturbance of reflexes
    • Clinical manifestations: wide base when standing, staggering, and pendular knee jerk

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    Description

    This quiz covers the structure and features of the cerebellum, including its origin, connections to the brain stem, and anatomical subdivisions.

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