6 Questions
What percentage of patients allergic to penicillins are also allergic to cephalosporins?
4-15%
Why are penicillins and cephalosporins not supposed to be used with bacteriostatic agents?
They may antagonize the effects of each other
Why can cephalosporins be used with some patients allergic to penicillins?
Cephalosporins have a different mode of action than penicillins
What is the scientific rationale for antibiotic prophylaxis in dentistry?
To eliminate or reduce transient bacteraemia caused by invasive dental procedures
What is the main concern addressed by antibiotic prophylaxis in dentistry?
Infective endocarditis
What is the term used for infection in a confined region from which pathogens travel to other regions of the body?
Focal infection
Study Notes
Antibiotic Allergies and Interactions
- Approximately 10% of patients allergic to penicillins are also allergic to cephalosporins.
- Penicillins and cephalosporins should not be used with bacteriostatic agents, as they can interfere with the bactericidal effects of these antibiotics.
Cephalosporins and Penicillin Allergies
- Cephalosporins can be used with some patients allergic to penicillins, as they have a different side chain and are less likely to cross-react.
Antibiotic Prophylaxis in Dentistry
- The scientific rationale for antibiotic prophylaxis in dentistry is to prevent bacterial endocarditis and other infections in susceptible patients.
- The main concern addressed by antibiotic prophylaxis in dentistry is the risk of infection, particularly in patients with pre-existing heart conditions, prosthetic joints, or compromised immune systems.
Infection Types
- The term used to describe infection in a confined region from which pathogens travel to other regions of the body is metastatic infection.
Test your knowledge of antibiotics with this quiz on cephalosporins. Learn about their usage, cross-reactivity with penicillins, and interactions with bacteriostatic agents.
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