Cephalosporins Quiz
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Questions and Answers

What percentage of patients allergic to penicillins are also allergic to cephalosporins?

  • 30-40%
  • 20-30%
  • 4-15% (correct)
  • 1-4%

Why are penicillins and cephalosporins not supposed to be used with bacteriostatic agents?

  • They lose their antibiotic activity
  • They become toxic to the body
  • They may cause allergic reactions
  • They may antagonize the effects of each other (correct)

Why can cephalosporins be used with some patients allergic to penicillins?

  • Cephalosporins have a different mode of action than penicillins (correct)
  • The allergic reactions to penicillins are usually mild
  • Cephalosporins do not contain beta-lactam rings
  • Cephalosporins have lower antigenic potential than penicillins

What is the scientific rationale for antibiotic prophylaxis in dentistry?

<p>To eliminate or reduce transient bacteraemia caused by invasive dental procedures (A)</p> Signup and view all the answers

What is the main concern addressed by antibiotic prophylaxis in dentistry?

<p>Infective endocarditis (C)</p> Signup and view all the answers

What is the term used for infection in a confined region from which pathogens travel to other regions of the body?

<p>Focal infection (D)</p> Signup and view all the answers

Flashcards

Penicillin/Cephalosporin Allergy

4-15% of penicillin-allergic patients also have a cephalosporin allergy.

Antibiotic antagonism

Penicillins and cephalosporins shouldn't be used with bacteriostatic agents because they can counteract each other's effects.

Cephalosporin Use in Penicillin Allergy

Cephalosporins have a different mechanism of action than penicillins, allowing some patients allergic to penicillins to tolerate cephalosporins.

Dental Antibiotic Prophylaxis

A preventive measure to reduce or eliminate transient bacteria in the blood caused by dental procedures to avoid infective endocarditis.

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Dental Prophylaxis Concern

Antibiotic prophylaxis in dentistry specifically focuses on preventing infective endocarditis.

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Focal Infection

An infection contained in one area that can spread to other regions of the body.

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Study Notes

Antibiotic Allergies and Interactions

  • Approximately 10% of patients allergic to penicillins are also allergic to cephalosporins.
  • Penicillins and cephalosporins should not be used with bacteriostatic agents, as they can interfere with the bactericidal effects of these antibiotics.

Cephalosporins and Penicillin Allergies

  • Cephalosporins can be used with some patients allergic to penicillins, as they have a different side chain and are less likely to cross-react.

Antibiotic Prophylaxis in Dentistry

  • The scientific rationale for antibiotic prophylaxis in dentistry is to prevent bacterial endocarditis and other infections in susceptible patients.
  • The main concern addressed by antibiotic prophylaxis in dentistry is the risk of infection, particularly in patients with pre-existing heart conditions, prosthetic joints, or compromised immune systems.

Infection Types

  • The term used to describe infection in a confined region from which pathogens travel to other regions of the body is metastatic infection.

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Description

Test your knowledge of antibiotics with this quiz on cephalosporins. Learn about their usage, cross-reactivity with penicillins, and interactions with bacteriostatic agents.

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