Cephalosporins Generations Quiz

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Questions and Answers

Which of the following is a fourth generation cephalosporin?

  • Cefazolin
  • Cefepime (correct)
  • Ceftaroline
  • Cefuroxime

Which of the following cephalosporins belongs to the second generation?

  • Cefotaxime
  • Cefalexin
  • Cefoxitin (correct)
  • Ceftriaxone

Which cephalosporin is a fifth generation drug?

  • Ceftazidime
  • Cefuroxime
  • Cefepime
  • Ceftaroline (correct)

What is a common characteristic of third generation cephalosporins?

<p>They have a broader spectrum of activity against gram-negative bacteria. (C)</p> Signup and view all the answers

Which cephalosporin is typically used as a first generation agent?

<p>Cefazolin (B)</p> Signup and view all the answers

Which of these cephalosporins is predominantly used for surgical prophylaxis?

<p>Cefazolin (A)</p> Signup and view all the answers

Which cephalosporin has the broadest activity against gram-negative bacteria among the options provided?

<p>Cefepime (B)</p> Signup and view all the answers

Which cephalosporin is primarily used for the treatment of pneumonia caused by resistant strains?

<p>Ceftaroline (B)</p> Signup and view all the answers

Which of the following cephalosporins is least likely to be used for urinary tract infections?

<p>Ceftazidime (D)</p> Signup and view all the answers

Which cephalosporin is specifically designed to treat infections caused by both gram-negative bacteria and anaerobes?

<p>Cefoxitin (D)</p> Signup and view all the answers

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Study Notes

Classification of Cefalosporins

  • Cefepime: Fourth generation; known for broad-spectrum activity, particularly against Gram-negative bacteria.
  • Cefuroxime: Second generation; effective against respiratory tract infections and has some resistance to β-lactamases.
  • Cefazolin: First generation; often used for surgical prophylaxis, effective against Gram-positive cocci.
  • Cefotaxime: Third generation; good penetration into the central nervous system, used for severe infections such as meningitis.
  • Ceftaroline: Fifth generation; specifically targets MRSA (methicillin-resistant Staphylococcus aureus) and other resistant strains.
  • Ceftazidime: Third generation; particularly effective against Pseudomonas aeruginosa and useful in treating nosocomial infections.
  • Cefalexin: First generation; commonly used for skin and soft tissue infections, well absorbed orally.
  • Ceftriaxone: Third generation; often used for treating gonorrhea and has a long half-life, allowing for once-daily dosing.
  • Cefoxitin: Second generation; effective against anaerobic bacteria, often used in intra-abdominal infections.
  • Cefaclor: Second generation; effective against various infections, particularly in respiratory and urinary tracts.

Classification of Cefalosporins

  • Cefepime: Fourth generation; known for broad-spectrum activity, particularly against Gram-negative bacteria.
  • Cefuroxime: Second generation; effective against respiratory tract infections and has some resistance to β-lactamases.
  • Cefazolin: First generation; often used for surgical prophylaxis, effective against Gram-positive cocci.
  • Cefotaxime: Third generation; good penetration into the central nervous system, used for severe infections such as meningitis.
  • Ceftaroline: Fifth generation; specifically targets MRSA (methicillin-resistant Staphylococcus aureus) and other resistant strains.
  • Ceftazidime: Third generation; particularly effective against Pseudomonas aeruginosa and useful in treating nosocomial infections.
  • Cefalexin: First generation; commonly used for skin and soft tissue infections, well absorbed orally.
  • Ceftriaxone: Third generation; often used for treating gonorrhea and has a long half-life, allowing for once-daily dosing.
  • Cefoxitin: Second generation; effective against anaerobic bacteria, often used in intra-abdominal infections.
  • Cefaclor: Second generation; effective against various infections, particularly in respiratory and urinary tracts.

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