Central Sensitization 101
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Questions and Answers

What is central sensitization?

  • A state in which pain can be triggered by less intense inputs and maintained by less intense inputs or by a different kind of input (correct)
  • A state in which pain can only be triggered by intense inputs
  • A state in which pain can be triggered by any input
  • A state in which pain cannot be triggered by any input
  • What are the possible mechanisms involved in central sensitization?

  • Increased membrane excitability, synaptic facilitation, decreased activity of the inhibitory neurons, enlargement of receptive fields (correct)
  • Increased membrane excitability, synaptic inhibition, decreased activity of the inhibitory neurons, enlargement of receptive fields
  • Decreased membrane excitability, synaptic facilitation, increased activity of the inhibitory neurons, reduction of receptive fields
  • Decreased membrane excitability, synaptic inhibition, increased activity of the inhibitory neurons, reduction of receptive fields
  • Is nociceptive input required to trigger central sensitization?

  • Nociceptive input is not related to central sensitization
  • Yes, nociceptive input is required to trigger central sensitization (correct)
  • No, nociceptive input is not required to trigger central sensitization
  • Central sensitization can only be triggered by nociceptive input
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