Podcast
Questions and Answers
Which molecule is NOT considered an electron carrier?
Which molecule is NOT considered an electron carrier?
- FAD
- ATP (correct)
- NAD+
- NAD
What role do NAD and FAD primarily serve in metabolic processes?
What role do NAD and FAD primarily serve in metabolic processes?
- They regulate cellular respiration rates.
- They accept or donate high energy electrons. (correct)
- They act as catalysts for biochemical reactions.
- They act as energy storage molecules.
What happens to NAD+ after it accepts electrons during the breakdown of glucose?
What happens to NAD+ after it accepts electrons during the breakdown of glucose?
- It is released as waste.
- It becomes NADH. (correct)
- It converts into ATP.
- It gets transformed into glucose.
High energy electrons are produced during which process?
High energy electrons are produced during which process?
Which of the following statements about electron carriers is true?
Which of the following statements about electron carriers is true?
What is the primary role of the Electron Transfer Chain (ETC) in cellular metabolism?
What is the primary role of the Electron Transfer Chain (ETC) in cellular metabolism?
Which complexes in the Electron Transfer Chain are classified as proton pumps?
Which complexes in the Electron Transfer Chain are classified as proton pumps?
What is the function of ATP synthase in cellular respiration?
What is the function of ATP synthase in cellular respiration?
How many ATP molecules can be produced from one molecule of glucose during cellular respiration?
How many ATP molecules can be produced from one molecule of glucose during cellular respiration?
What key role does the citric acid cycle play in ATP production?
What key role does the citric acid cycle play in ATP production?
What is a major source of fuel in diets according to the content?
What is a major source of fuel in diets according to the content?
Which factor is NOT mentioned as affecting cellular metabolism?
Which factor is NOT mentioned as affecting cellular metabolism?
What role do digestive enzymes play in metabolism?
What role do digestive enzymes play in metabolism?
Which of the following is classified as a metabolic disease?
Which of the following is classified as a metabolic disease?
What occurs when there are faults in enzymes related to metabolism?
What occurs when there are faults in enzymes related to metabolism?
Which of the following is considered a basic component of digested food?
Which of the following is considered a basic component of digested food?
How does malnutrition impact metabolism?
How does malnutrition impact metabolism?
What is a potential clinical issue with abnormal lactate generation?
What is a potential clinical issue with abnormal lactate generation?
What are metabolites primarily converted from?
What are metabolites primarily converted from?
Which of the following diseases is NOT specifically listed as impacting metabolism?
Which of the following diseases is NOT specifically listed as impacting metabolism?
How many ATP molecules are produced from glycolysis?
How many ATP molecules are produced from glycolysis?
What is the total amount of ATP produced from the electron transfer phase?
What is the total amount of ATP produced from the electron transfer phase?
What is the combined total of ATP produced when glycolysis, citric acid cycle, and electron transfer are summed?
What is the combined total of ATP produced when glycolysis, citric acid cycle, and electron transfer are summed?
Which component of metabolism is primarily responsible for the complexity mentioned?
Which component of metabolism is primarily responsible for the complexity mentioned?
Which of the following textbooks is recommended for advanced biochemistry?
Which of the following textbooks is recommended for advanced biochemistry?
What primary molecule is produced from the oxidation of pyruvate in the mitochondria?
What primary molecule is produced from the oxidation of pyruvate in the mitochondria?
Which enzyme is responsible for the conversion of pyruvate to acetyl CoA?
Which enzyme is responsible for the conversion of pyruvate to acetyl CoA?
Where does the conversion of pyruvate to acetyl CoA occur?
Where does the conversion of pyruvate to acetyl CoA occur?
What cycle does acetyl CoA enter after its formation?
What cycle does acetyl CoA enter after its formation?
What are the main high-energy electron carriers produced in the Citric Acid Cycle?
What are the main high-energy electron carriers produced in the Citric Acid Cycle?
Which metabolic process continuously produces pyruvate for the Citric Acid Cycle?
Which metabolic process continuously produces pyruvate for the Citric Acid Cycle?
What type of reaction occurs when pyruvate is converted to acetyl CoA?
What type of reaction occurs when pyruvate is converted to acetyl CoA?
What happens to the CO2 produced during the Citric Acid Cycle?
What happens to the CO2 produced during the Citric Acid Cycle?
What is the relationship between glycolysis and the Citric Acid Cycle?
What is the relationship between glycolysis and the Citric Acid Cycle?
What is another name for the Citric Acid Cycle?
What is another name for the Citric Acid Cycle?
What is the primary substrate used in glycolysis?
What is the primary substrate used in glycolysis?
Which product is formed at the end of glycolysis?
Which product is formed at the end of glycolysis?
What phase of glycolysis requires the input of ATP?
What phase of glycolysis requires the input of ATP?
During which phase of glycolysis is ATP produced?
During which phase of glycolysis is ATP produced?
What type of phosphorylation occurs during the ATP generation in glycolysis?
What type of phosphorylation occurs during the ATP generation in glycolysis?
How many chemical reactions are involved in glycolysis?
How many chemical reactions are involved in glycolysis?
Which molecule is converted to G3P during glycolysis?
Which molecule is converted to G3P during glycolysis?
What process connects glycolysis to the next stage of cellular respiration?
What process connects glycolysis to the next stage of cellular respiration?
In which cellular location does glycolysis occur?
In which cellular location does glycolysis occur?
What is the fate of the phosphate group during the conversion of PEP to pyruvate?
What is the fate of the phosphate group during the conversion of PEP to pyruvate?
What intermediate product is generated in the conversion of glucose during glycolysis?
What intermediate product is generated in the conversion of glucose during glycolysis?
Which of the following statements about the two major stages of glycolysis is true?
Which of the following statements about the two major stages of glycolysis is true?
What is the purpose of glycolysis in cellular metabolism?
What is the purpose of glycolysis in cellular metabolism?
What molecule is produced during the payoff phase of glycolysis other than ATP?
What molecule is produced during the payoff phase of glycolysis other than ATP?
What role do enzymes play in the glycolytic process?
What role do enzymes play in the glycolytic process?
Flashcards
Electron Carrier
Electron Carrier
A molecule capable of accepting or donating electrons during metabolic reactions. Effectively transfers energy stored in electrons.
NAD+
NAD+
A coenzyme derived from vitamin B3 (niacin) that plays a crucial role in cellular respiration, particularly in glycolysis and the citric acid cycle. It accepts electrons and becomes NADH, carrying energy.
FAD
FAD
A cofactor derived from vitamin B2 (riboflavin) that carries electrons and hydrogen atoms. It is involved in the electron transport chain, a crucial stage of cellular respiration.
Oxidation
Oxidation
Signup and view all the flashcards
Reduction
Reduction
Signup and view all the flashcards
Metabolism
Metabolism
Signup and view all the flashcards
Catabolism
Catabolism
Signup and view all the flashcards
Anabolism
Anabolism
Signup and view all the flashcards
Glucose
Glucose
Signup and view all the flashcards
Carbohydrate digestion
Carbohydrate digestion
Signup and view all the flashcards
Fat digestion
Fat digestion
Signup and view all the flashcards
Protein digestion
Protein digestion
Signup and view all the flashcards
Metabolic disorders
Metabolic disorders
Signup and view all the flashcards
Pharmacogenetics
Pharmacogenetics
Signup and view all the flashcards
Homeostasis
Homeostasis
Signup and view all the flashcards
Glycolysis
Glycolysis
Signup and view all the flashcards
Citric Acid Cycle
Citric Acid Cycle
Signup and view all the flashcards
Electron Transfer Chain (ETC)
Electron Transfer Chain (ETC)
Signup and view all the flashcards
ATP Synthase
ATP Synthase
Signup and view all the flashcards
ATP Yield from Glucose
ATP Yield from Glucose
Signup and view all the flashcards
What is pyruvate?
What is pyruvate?
Signup and view all the flashcards
What does pyruvate dehydrogenase (PDH) do?
What does pyruvate dehydrogenase (PDH) do?
Signup and view all the flashcards
What is acetyl CoA?
What is acetyl CoA?
Signup and view all the flashcards
What is the citric acid cycle?
What is the citric acid cycle?
Signup and view all the flashcards
What is the relationship between glycolysis and the citric acid cycle?
What is the relationship between glycolysis and the citric acid cycle?
Signup and view all the flashcards
How does the citric acid cycle contribute to energy production?
How does the citric acid cycle contribute to energy production?
Signup and view all the flashcards
What is the role of carbon dioxide in the citric acid cycle?
What is the role of carbon dioxide in the citric acid cycle?
Signup and view all the flashcards
What is the electron transport chain?
What is the electron transport chain?
Signup and view all the flashcards
What is ATP and how is it generated?
What is ATP and how is it generated?
Signup and view all the flashcards
What is the starting material in Glycolysis?
What is the starting material in Glycolysis?
Signup and view all the flashcards
What is the product of Glycolysis?
What is the product of Glycolysis?
Signup and view all the flashcards
What is the purpose of the first stage in Glycolysis?
What is the purpose of the first stage in Glycolysis?
Signup and view all the flashcards
What happens during the second stage of Glycolysis?
What happens during the second stage of Glycolysis?
Signup and view all the flashcards
What is substrate-level phosphorylation?
What is substrate-level phosphorylation?
Signup and view all the flashcards
What is the role of NAD+ in Glycolysis?
What is the role of NAD+ in Glycolysis?
Signup and view all the flashcards
What is phosphoenolpyruvate (PEP)?
What is phosphoenolpyruvate (PEP)?
Signup and view all the flashcards
How many reactions occur in Glycolysis?
How many reactions occur in Glycolysis?
Signup and view all the flashcards
What is pyruvate processing?
What is pyruvate processing?
Signup and view all the flashcards
Why is glycolysis important?
Why is glycolysis important?
Signup and view all the flashcards
What is anaerobic respiration?
What is anaerobic respiration?
Signup and view all the flashcards
What is lactic acid fermentation?
What is lactic acid fermentation?
Signup and view all the flashcards
Study Notes
Cellular Respiration Overview
- Cellular respiration breaks down glucose into smaller molecules to create ATP, the cell's energy currency
- This occurs in a series of four stages: glycolysis, pyruvate processing, the citric acid cycle, and the electron transport chain
- The process involves oxidation-reduction reactions, transferring electrons to create energy for ATP production
Glycolysis
- Glycolysis is the first stage of cellular respiration, occurring in the cytoplasm
- Glucose is broken down into pyruvate (2 molecules)
- This process uses ATP in the initial stages but results in a net gain of ATP
- Net production = 2 ATP, 2 NADH
Pyruvate Processing
- Pyruvate is oxidized to acetyl CoA inside the mitochondria
- This converts pyruvate into Acetyl CoA
- This produces 2 NADH and 2 CO2 per glucose molecule
Citric Acid Cycle
- Acetyl CoA enters the Citric Acid Cycle (also known as the Krebs Cycle) in the mitochondrial matrix
- It involves a series of redox reactions that produce ATP, NADH and FADH2
- Net products per glucose are 2 ATP, 6 NADH, and 2 FADH2
Electron Transport Chain
- The electron transport chain (ETC) is the final stage
- Electrons from NADH and FADH2 are passed down the chain, releasing energy that is used to pump protons into the intermembrane space
- This creates a proton gradient used by ATP synthase to generate ATP
- Oxygen acts as the final electron acceptor, forming water
- The ETC produces a significant number of ATP
ATP Synthase
- The electron transport chain creates a gradient of protons (H+) between the inner and outer membrane within the mitochondria
- ATP synthase is an enzyme that utilizes the flow of these protons to generate ATP
- This is crucial in driving further cellular processes
NAD+ and FAD
- NAD+ and FAD are electron carriers that move high energy electrons during the process.
- NADH delivers electrons to the electron transport chain (ETC)
- FADH2 also delivers electrons to the ETC, generating ATP.
What happens when oxygen is not present?
- Cells can still produce ATP when oxygen is not available but the yield of ATP molecules is very low. The process is called anaerobic respiration or fermentation
- In anaerobic conditions pyruvate is converted to lactate through lactate dehydrogenase (LDH)
- In the absence of oxygen, NADH must be recycled back to NAD+ - which glycolysis needs for pyruvate processing.
Gluconeogenesis
- When glucose levels are low, the body uses pyruvate to create glucose with the enzyme gluconeogenesis
- The process is in the liver
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.