24 Questions
Which of the following is the most abundant lipid in cellular membranes?
Phospholipids
Which of the following is NOT a function of the ER (Endoplasmic Reticulum)?
Oxidation (detoxification) of substrates
Most proteins in the ER are glycosylated by addition of a preformed oligosaccharide chain to the side chain NH2 group of an asparagine. Only asparagines in the following sequences become glycosylated (identify two).
Asn-X-Ser
Which statement below about lipid rafts is incorrect?
There are no transmembrane proteins in the raft domains.
Which description(s) below about the ABC transporters is (are) correct?
All of the above
Which enzyme transfers lipid molecules from the cytosolic half to the lumenal half of the ER membrane?
Scramblase
Which of the following is NOT a mediator of protein nuclear import?
RING domain
In healthy cells, which lipid molecules are present only in the inner membrane?
Phosphatidyl-serine
Which of the following descriptions about transmembrane proteins is incorrect?
Intra- and inter-chain disulfide bonds are all on the noncytosolic domain of the proteins.
Which statement about signal sequences is incorrect?
The signal sequences of different proteins destined for the same intracellular organelles have identical amino acid sequences.
What is the most abundant lipid in cellular membranes?
Phospholipids
Which of the following is NOT a function of the Endoplasmic Reticulum (ER)?
Oxidation (detoxification) of substrates
Which statement below about lipid rafts is incorrect?
There are no transmembrane proteins in the raft domains.
Which description(s) below about the ABC transporters is (are) correct?
All of the above
To which structure is the cell nucleus topologically equivalent?
Cytosol
In N-linked glycosylation, which sequence of amino acids allows glycosylation to occur?
Asn-X-Ser
Which enzyme transfers lipid molecules from the cytosolic half to the lumenal half of the ER membrane?
Scramblase
Which of the following is NOT a mediator of protein nuclear import?
RING domain
In healthy cells, which lipid molecules are present only in the inner membrane?
Phosphatidyl-serine
Which of the following descriptions about transmembrane proteins is incorrect?
Intra- and inter-chain disulfide bonds are all on the noncytosolic domain of the proteins.
Which statement about signal sequences is incorrect?
The signal sequences of different proteins destined for the same intracellular organelles have identical amino acid sequences.
Which description below about peroxisomes is incorrect?
The import signals are either 3 AA at the C-terminus or a signal sequence at N-terminus.
Which description below about Rab proteins is incorrect?
The interactions between Rab effector proteins and Rab proteins establish the first wee connection between the vesicle and target membranes.
Which of the following statements about transmembrane proteins is incorrect?
Intra- and inter-chain disulfide bonds are all on the extracellular domain of the proteins.
Test your knowledge on cellular membranes and endoplasmic reticulum (ER) functions with this multiple-choice quiz. Questions cover topics such as the most abundant lipids in cellular membranes, ER functions, and protein glycosylation in the ER.
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