Cellular Membranes and ER Functions Quiz
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Questions and Answers

Which of the following is the most abundant lipid in cellular membranes?

  • Cholesterol
  • Phospholipids (correct)
  • Glucolipids
  • Phosphoinositol

Which of the following is NOT a function of the ER (Endoplasmic Reticulum)?

  • Transportation of proteins and carbohydrates to organelles
  • Ca. storage and release
  • Oxidation (detoxification) of substrates (correct)
  • Biosynthesis of proteins (including all transmembrane proteins), lipids, and glycogen

Most proteins in the ER are glycosylated by addition of a preformed oligosaccharide chain to the side chain NH2 group of an asparagine. Only asparagines in the following sequences become glycosylated (identify two).

  • Asn-X-Thr
  • Asn-X-Ser (correct)
  • Thr-X-Asn
  • Ser-X-Asn

Which statement below about lipid rafts is incorrect?

<p>There are no transmembrane proteins in the raft domains. (C)</p> Signup and view all the answers

Which description(s) below about the ABC transporters is (are) correct?

<p>All of the above (D)</p> Signup and view all the answers

Which enzyme transfers lipid molecules from the cytosolic half to the lumenal half of the ER membrane?

<p>Scramblase (B)</p> Signup and view all the answers

Which of the following is NOT a mediator of protein nuclear import?

<p>RING domain (C)</p> Signup and view all the answers

In healthy cells, which lipid molecules are present only in the inner membrane?

<p>Phosphatidyl-serine (A)</p> Signup and view all the answers

Which of the following descriptions about transmembrane proteins is incorrect?

<p>Intra- and inter-chain disulfide bonds are all on the noncytosolic domain of the proteins. (B)</p> Signup and view all the answers

Which statement about signal sequences is incorrect?

<p>The signal sequences of different proteins destined for the same intracellular organelles have identical amino acid sequences. (C)</p> Signup and view all the answers

What is the most abundant lipid in cellular membranes?

<p>Phospholipids (D)</p> Signup and view all the answers

Which of the following is NOT a function of the Endoplasmic Reticulum (ER)?

<p>Oxidation (detoxification) of substrates (B)</p> Signup and view all the answers

Which statement below about lipid rafts is incorrect?

<p>There are no transmembrane proteins in the raft domains. (C)</p> Signup and view all the answers

Which description(s) below about the ABC transporters is (are) correct?

<p>All of the above (D)</p> Signup and view all the answers

To which structure is the cell nucleus topologically equivalent?

<p>Cytosol (D)</p> Signup and view all the answers

In N-linked glycosylation, which sequence of amino acids allows glycosylation to occur?

<p>Asn-X-Ser (B)</p> Signup and view all the answers

Which enzyme transfers lipid molecules from the cytosolic half to the lumenal half of the ER membrane?

<p>Scramblase (D)</p> Signup and view all the answers

Which of the following is NOT a mediator of protein nuclear import?

<p>RING domain (B)</p> Signup and view all the answers

In healthy cells, which lipid molecules are present only in the inner membrane?

<p>Phosphatidyl-serine (D)</p> Signup and view all the answers

Which of the following descriptions about transmembrane proteins is incorrect?

<p>Intra- and inter-chain disulfide bonds are all on the noncytosolic domain of the proteins. (B)</p> Signup and view all the answers

Which statement about signal sequences is incorrect?

<p>The signal sequences of different proteins destined for the same intracellular organelles have identical amino acid sequences. (C)</p> Signup and view all the answers

Which description below about peroxisomes is incorrect?

<p>The import signals are either 3 AA at the C-terminus or a signal sequence at N-terminus. (C)</p> Signup and view all the answers

Which description below about Rab proteins is incorrect?

<p>The interactions between Rab effector proteins and Rab proteins establish the first wee connection between the vesicle and target membranes. (D)</p> Signup and view all the answers

Which of the following statements about transmembrane proteins is incorrect?

<p>Intra- and inter-chain disulfide bonds are all on the extracellular domain of the proteins. (B)</p> Signup and view all the answers

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