Podcast
Questions and Answers
What is the precursor of steroid hormones, vitamin D, and bile acids?
What is the precursor of steroid hormones, vitamin D, and bile acids?
Which lipid is the simplest phospholipid?
Which lipid is the simplest phospholipid?
What are the structural features shared by phospholipids, sphingolipids, and cholesterol?
What are the structural features shared by phospholipids, sphingolipids, and cholesterol?
Which lipid is formed by the combination of two phospholipids?
Which lipid is formed by the combination of two phospholipids?
Signup and view all the answers
What are the functions of flippases in cells?
What are the functions of flippases in cells?
Signup and view all the answers
Which biochemical property is associated with lipid rafts in cellular membranes?
Which biochemical property is associated with lipid rafts in cellular membranes?
Signup and view all the answers
What is the rate limiting step in bile acid synthesis?
What is the rate limiting step in bile acid synthesis?
Signup and view all the answers
When intracellular cholesterol levels are low, is HMG CoA reductase phosphorylated or unphosphorylated?
When intracellular cholesterol levels are low, is HMG CoA reductase phosphorylated or unphosphorylated?
Signup and view all the answers
Where is SCAP-SREBP located when cholesterol levels are low?
Where is SCAP-SREBP located when cholesterol levels are low?
Signup and view all the answers
What is the mechanism of action of statins?
What is the mechanism of action of statins?
Signup and view all the answers
Which organ STORES bile acids and bile salts?
Which organ STORES bile acids and bile salts?
Signup and view all the answers
What is the common feature among all cellular membrane lipids?
What is the common feature among all cellular membrane lipids?
Signup and view all the answers
Which lipid class is primarily synthesized in the Golgi apparatus?
Which lipid class is primarily synthesized in the Golgi apparatus?
Signup and view all the answers
What is the function of lipid flippases in cellular membranes?
What is the function of lipid flippases in cellular membranes?
Signup and view all the answers
Which lipid is the only phospholipid that is antigenic, meaning it is immunogenic?
Which lipid is the only phospholipid that is antigenic, meaning it is immunogenic?
Signup and view all the answers
In apoptosis, what is one of the hallmarks observed on the outer face of the plasma membrane?
In apoptosis, what is one of the hallmarks observed on the outer face of the plasma membrane?
Signup and view all the answers
What is the primary difference between apoptosis and necrosis?
What is the primary difference between apoptosis and necrosis?
Signup and view all the answers
'Ceramide' in sphingolipids consists of which two components attached by an amide linkage?
'Ceramide' in sphingolipids consists of which two components attached by an amide linkage?
Signup and view all the answers
'Phosphatidylethanolamine' belongs to which class of lipids?
'Phosphatidylethanolamine' belongs to which class of lipids?
Signup and view all the answers
'Mitomycin C' is known for inducing which process in cells?
'Mitomycin C' is known for inducing which process in cells?
Signup and view all the answers
What is the function of 'Scramblase' in cellular membranes?
What is the function of 'Scramblase' in cellular membranes?
Signup and view all the answers
What is the function of phosphatidylserine exposure during apoptosis?
What is the function of phosphatidylserine exposure during apoptosis?
Signup and view all the answers
Which process moves phosphatidylserine from the cytoplasmic face to the extracellular face of the plasma membrane during apoptosis?
Which process moves phosphatidylserine from the cytoplasmic face to the extracellular face of the plasma membrane during apoptosis?
Signup and view all the answers
What is a characteristic feature of lipid rafts in cellular membranes?
What is a characteristic feature of lipid rafts in cellular membranes?
Signup and view all the answers
What is the role of lipid rafts in cellular functions?
What is the role of lipid rafts in cellular functions?
Signup and view all the answers
How does phosphatidylserine on apoptotic bodies help in clearance by phagocytes?
How does phosphatidylserine on apoptotic bodies help in clearance by phagocytes?
Signup and view all the answers
What type of proteins specifically partition to lipid rafts?
What type of proteins specifically partition to lipid rafts?
Signup and view all the answers
Which organelle is primarily responsible for the synthesis of cholesterol?
Which organelle is primarily responsible for the synthesis of cholesterol?
Signup and view all the answers
What is the primary function of HMG CoA reductase in cholesterol synthesis?
What is the primary function of HMG CoA reductase in cholesterol synthesis?
Signup and view all the answers
Which enzyme is responsible for the two-step cleavage of SREBP during cholesterol synthesis regulation?
Which enzyme is responsible for the two-step cleavage of SREBP during cholesterol synthesis regulation?
Signup and view all the answers
What is the role of SCAP (SREBP Cleavage Activating Protein) in cholesterol synthesis regulation?
What is the role of SCAP (SREBP Cleavage Activating Protein) in cholesterol synthesis regulation?
Signup and view all the answers
How do statins primarily affect cholesterol synthesis?
How do statins primarily affect cholesterol synthesis?
Signup and view all the answers
What effect does glucagon have on HMGR expression and activity?
What effect does glucagon have on HMGR expression and activity?
Signup and view all the answers
Which drug primarily acts at the small intestine brush border to inhibit cholesterol absorption?
Which drug primarily acts at the small intestine brush border to inhibit cholesterol absorption?
Signup and view all the answers
What is a key advantage of using Zetia (ezetimibe) in reducing cholesterol levels?
What is a key advantage of using Zetia (ezetimibe) in reducing cholesterol levels?
Signup and view all the answers
